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Scientists pave the way for fast, cost-effective custom enzyme development

Researchers at Nagoya University have developed a new method called SMART that accelerates enzyme evolution and reduces costs by accelerating the selection period from weeks to days. The system uses mRNA display, next-generation sequencing, and bioinformatics to identify superior enzyme variants.

SourceNagoya University·JournalACS Synthetic Biology·TypeExperimental study·DateApr 29, 2026

Robots map chemical reaction “hyperspaces” to unlock complex networks

Researchers at CARS create detailed maps of chemical reactivity, discovering regions of unexpected outcomes and reconstructing intricate reaction networks. This new understanding enables control over the formation of different major products from a set of starting materials.

SourceInstitute for Basic Science·JournalNature·TypeExperimental study·DateSep 24, 2025
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Researchers uncover potential biosignatures on Mars

A new study has revealed chemical signatures of ancient Martian microbial life in the Bright Angel formation, a region of Jezero Crater known for its fine-grained mudstones rich in oxidized iron and organic carbon. The findings suggest that early microorganisms may have played a role in shaping these rocks through redox reactions.

SourceTexas A&M University·JournalNature·DateSep 10, 2025

Controlling matter at the atomic level: University of Bath breakthrough

Researchers achieved control over competing reaction outcomes by selectively manipulating charge states and specific resonances through targeted energy injection. This breakthrough has profound implications for pharmaceutical research, potentially improving efficiency and sustainability.

SourceUniversity of Bath·JournalNature Communications·TypeExperimental study·DateDec 3, 2024

Choosing outcomes: new switchable process for synthesizing 3-aminoindolines and 2’-aminoarylacetic acids from same substrate

Researchers at Okayama University developed a switchable process to synthesize 3-aminoindolines and 2'-aminoaryl acetic acids from a common substrate using Grignard reagents and azide compounds. The new protocol utilizes tautomerism to control chemoselectivity and achieves efficient synthesis with good yields.

SourceOkayama University·JournalChemical Communications·TypeExperimental study·DateJun 24, 2024
Apple iPhone 17 Pro

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Nonlinear photochromic properties in a perylene-substituted rhodamine spirolactam

Researchers developed a novel compound with nonlinear photochromic properties, achieving enhanced contrast and spatial resolution. The compound exhibits improved coloration efficiency with higher-intensity light, enabling diverse applications in photolithography, 3D printing, and optical disks.

SourceRitsumeikan University·JournalAngewandte Chemie International Edition·TypeExperimental study·DateMay 28, 2024

Electronic sensor the size of a single molecule a potential game-changer

Researchers at Curtin University have created a piezoresistor the size of a human hair, revolutionizing chemical and biosensors. This breakthrough enables detection of diseases through molecular shape changes, offering new possibilities for health monitoring devices.

SourceCurtin University·JournalNature Communications·TypeExperimental study·DateOct 3, 2023

Tip tricks control reactions in a single molecule

Scientists have developed a method to control chemical reactions in a single molecule by applying voltage pulses, resulting in unprecedented selectivity. By fine-tuning the voltage, researchers can interconvert different products formed during the reaction.

SourceKing Abdullah University of Science & Technology (KAUST)·JournalScience·DateAug 28, 2022

Researchers measure temperature effect of plasmon in chemical reactions using organic "sensors"

Scientists have developed a method to estimate the temperature of chemical reactions activated by plasmons, revealing that properties of plasmons depend on thermal effects and other factors. The study used organic molecules as ultra-small sensors, showing different temperatures for two molecules triggered by plasmon energy.

SourceTomsk Polytechnic University·JournalChemical Science·DateFeb 15, 2021

Chemists' surprising discovery of nanoconfined reactions could aid catalytic design

Researchers at Georgia State University have made a groundbreaking discovery in catalytic reactions, revealing that nanoconfinement can actually speed up chemical reactions. This finding has major implications for the engineering of new, more energy-efficient catalysts that could save billions of barrels of gasoline every year.

SourceGeorgia State University·JournalNature Communications·DateNov 6, 2019
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Switched-on DNA

An ASU-led team has developed the first controllable DNA switch, allowing for reversible control of electricity flow within a single molecule. The modified DNA helix can conduct electricity and is reversibly controlled using an anthraquinone group.

SourceArizona State University·JournalNature Communications·DateFeb 20, 2017

How solvent molecules cooperate in reactions

Researchers discovered that solvent molecules can significantly impact the formation of an ether molecule, even when they don't directly participate in the reaction. A second methanol molecule is essential for the reaction to occur, indicating that solvent molecules are not just bystanders but rather assistants.

SourceRuhr-University Bochum·JournalNature Communications·DateOct 6, 2016

Pushing a single-molecule switch

Researchers activate a single molecule switch using an atomic-force probe, revealing the need for precise positioning and chemical reactivity. The study's findings could lead to new control of chemistry at the atomic level.

SourceUniversity of the Basque Country·JournalNature Chemistry·DateJul 15, 2016

2 catalysts are better than 1

Researchers have successfully used two catalysts to produce valuable compounds for biomedical research. The cooperative catalysis approach allows for rapid, efficient and controlled production of large amounts of a key building block for many pharmaceuticals.

SourceNorthwestern University·JournalNature Chemistry·DateJul 27, 2010
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