Articles tagged with Solubility
The journal features novel FAK-paxillin inhibitors, a venom toxin screening platform, and AI-driven solubility prediction for compound discovery. SLAS Discovery highlights innovative technologies to understand and treat human disease.
Scientists from Institute of Science Tokyo successfully solubilize porous aromatic polymers (PAPs) in water using aromatic micelles, forming giant polycavity materials with high incorporation functions. The method enables the preparation of rare multi-component materials with potential applications in advanced functional materials.
Scientists from SANKEN at Osaka University created an electrically controlled nanogate that can be tailored for specific molecules. The gate's diameter was adjusted using voltage, leading to distinct ion transport behaviors. This technology has the potential to enable precise control over molecule transport and reaction systems.
Temperature-sensitive emulsions offer a new method to control when droplets dissolve, enabling precise targeting of medicines to specific areas in the body. The discovery could revolutionize methods of delivering medication in higher concentrations to diseased areas.
Researchers develop a method to synthesize bare aromatic polymers using dendrimer support, enabling high solubility and transfer to other materials. This innovation opens up new possibilities for creating hybrid materials with unique properties.
Researchers develop a multifunctional supramolecular catalysis protocol using open-cage solutions to achieve diverse cage-confined catalysis. The protocol enables selective mass transfer, C-H activation, and anionic intermediate stabilization, promoting acid/base-catalyzed cascade reactions.
A team of four scientists from Hokkaido University developed a rapid and efficient protocol for cross-coupling reactions using ball milling, expanding the pool of chemicals usable in organic synthesis. They successfully applied this method to mostly-insoluble aryl halides, yielding desired products.
Researchers have developed a new technology to diagnose sickle cell disease with increased sensitivity and speed, using only a small droplet of blood and costing less than traditional methods. The Acousto Thermal Shift Assay (ATSA) measures protein interactions and mutations in under one minute.
Researchers have developed a novel amphiphilic AIE-active sensor that can overcome the traditional bioimaging bottleneck by achieving high targeting ability and selectivity. The sensor utilizes an amphiphilic characteristic to prevent aggregation in aqueous environments and ensure accurate fluorescence signal mapping.
A novel method to grow multi-layered, single-crystalline graphene with a selected stacking order in a wafer scale has been developed. The researchers used Cu-Si alloy formation to control the number of graphene layers, allowing for uniform large-area single-crystalline layer-tunable multilayer graphene growth.
Researchers developed tailored polyimide membranes to efficiently separate H2S and CO2 from sour gas. By adjusting the ratio of building blocks, they achieved balanced separation efficiency for both gases.
Scientists at Shinshu University have created a new method for growing rubies on sapphire using the flux method, which reduces energy consumption and environmental impact. The team studied the solubility curve of ruby crystal growth in Molybdenum Trioxide (MoO3) and found it to be crucial for precise crystal growth.
A team of international researchers has discovered a new phenomenon where partially miscible liquids deform the liquid-liquid interface. This finding is significant for oil recovery and CO2 injection processes, as it challenges traditional understanding of fluid dynamics in such systems. The study's results have implications for improv...
Osaka University researchers created a non-polymeric mixture with a lower critical solution temperature, exhibiting reversible transitions between a clear solution and a suspension. The system can change color depending on its state and will be useful for developing new thermo-responsive materials.
Scientists at VIB discover that mutations at specific positions can suppress protein aggregation, increasing solubility. This breakthrough could enable the production of protein drugs and enzymes with improved stability and functionality.
Researchers at Uppsala University discovered that Upsalite, a highly porous magnesium carbonate, can improve the solubility and bioavailability of poorly soluble drugs. By using Upsalite, about 40% of newly marketed drugs with poor solubility may have their therapeutic efficacy enhanced.
A cross-disciplinary team at the University of Maryland has designed molecular containers that can hold drug molecules and increase their solubility up to nearly 3000 times. The discovery opens possibilities for rehabilitating drug candidates and improving successful drugs with better solubility.
Researchers have discovered that sulphur plays a crucial role in forming gold deposits by enhancing gold solubility. The study's findings could lead to more successful gold exploration and mining practices.
Liu's research focuses on hydrophilic macro-ionic solutions, which form single-layer, hollow, spherical structures called 'blackberries.' These structures have unique properties and potential applications in biomedical materials.
A team of researchers from UC Davis has developed a simple model to predict the solubility of environmental contaminants in groundwater. The model uses hydrotalcites, layered compounds that can take up metals and other chemicals, to make predictions about contamination with chromium, carbon, iodine, and technetium isotopes.