Articles tagged with Micelles
Researchers quantify interactions of P407 micelles in PBS to understand gelation behavior and release mechanisms. The study reveals stronger attractive forces between micelles in saline, affecting gel stability and structural fluctuations.
In a mouse study, researchers successfully used RNA micelles to shrink metastasized tumors in lungs by delivering chemotherapy drugs and an RNA molecule that blocks cancer survival. The treatment significantly reduced tumor growth and improved outcomes for mice with colorectal cancer lung metastasis.
Scientists from Institute of Science Tokyo successfully solubilize porous aromatic polymers (PAPs) in water using aromatic micelles, forming giant polycavity materials with high incorporation functions. The method enables the preparation of rare multi-component materials with potential applications in advanced functional materials.
Researchers have developed a novel electrochemistry approach to build new molecules using micelles from naturally occurring amino acids and coconut oil. This breakthrough method could reduce the cost of making medicines by combining solvents, electrolytes, and reaction boosters into one simple tool.
Researchers at Rice University developed microscopic reactors capable of performing chemical reactions using water instead of toxic solvents. This innovation could drastically reduce pollution in industries including pharmaceuticals and materials science.
Researchers from Tokyo University of Science have developed a new type of micelle that can effectively dissolve dyes, paving the way for more efficient and cost-effective formulations. The micelles were created using block copolymers and showed improved dye solubilization capacity compared to random copolymers.
Researchers developed glucose-responsive micelles that encapsulate and protect glucagon, releasing it when blood sugar levels drop below a certain threshold. The micelles prevented hypoglycemia in mouse trials, achieving normal blood sugar levels within 40 minutes.
A team of scientists from Indian Institute of Science developed a surfactant from cashew nut shell liquid to catalyse industrially relevant reactions in water, leading to 80% higher product yields and replacing expensive catalysts. The study uses micellar catalysis to mimic biological systems.
Scientists improve stability and bioavailability of mRNA nanocarriers using triphenylphosphonium, leading to increased protein production in tumor tissues. The TPP-based system also shows higher mRNA levels in blood after 30 minutes compared to amine-based micelles.
Researchers at Tokyo Institute of Technology have developed alkyl-aromatic hybrid micelles that exhibit high stability in water and excellent host functions towards aromatic guests. The new amphiphiles feature a linear alkyl-chain flanked by two aromatic panels, forming an alkyl core surrounded by an aromatic shell.
Researchers at MIT developed GastroShield, a sprayable gel that prevents bleeding and leakage from weakened gastrointestinal tissues during endoscopic procedures. The gel forms a protective layer that reinforces tissue integrity and promotes healing.
Researchers developed a novel material that self-assembles into micelle structures targeting cancer cell lysosomes, specifically interacting with Cathepsin B. This leads to dysfunctional lysosomes and apoptotic death of cancer cells. The technology promises a new approach to combat drug resistance in cancer treatment.
Researchers developed a cancer-selective therapeutic agent that targets cancer cells' unique acidic pH microenvironment, inducing mitochondrial dysfunction and killing only cancer cells. The agent, Mito-SA, forms charge-shielded nano-assemblies that selectively disassemble in the tumoral environment.
Researchers discovered that positively charged micelles can significantly accelerate chemical reactions between like-charged molecules. By controlling the magnitude and spatial distribution of the electric charge on catalysts, reaction rates can be tuned within several orders of magnitude.
A team of scientists at PNNL created a new kind of micelle that detects SARS-CoV-2 in the air by bursting open upon contact with the virus, sending an immediate electronic signal. The detector has advantages over current technologies, requiring lower viral particle levels and producing fewer errors.
Researchers developed a biosensor using nanostructured and nanoporous surfaces to detect biomarkers in clinical samples, overcoming technical challenges of small sample amounts. The new technology can provide quick and accurate diagnoses for diseases like prostate cancer without needing dilution or preprocessing steps.
Researchers from Kazan Federal University discovered that micelle-forming polyurethane inhibitors can effectively inhibit hydrate formation. The study found that the presence of surface-active properties and ability to form micelles can hinder hydrate formation, providing a new mechanism for gas storage and flow assurance.
Researchers discovered a nanomaterial that boosts antibody production while minimizing inflammation, opening up new possibilities for vaccine development. The 'micelle' scaffolds can be used to generate laboratory-scale quantities of therapeutic antibodies against real-world pathogens.
Researchers have developed poly-ion complex (PIC) nanomicelles loaded with CPT1A inhibitors to deliver drugs into brain cells, reducing fatty acid oxidation and improving treatment for glioblastoma. The delivery system successfully increased cellular concentration of the cargo and biological activity.
Researchers developed advanced imaging methods to study the life cycle of liquid foams, revealing that micelles play a crucial role in determining foam stability. The findings could aid in developing new products and improving industrial processes.
Researchers at Tokyo Tech have developed a straightforward strategy to produce organic thin films with controllable shapes and thickness distributions. The novel approach combines bipolar electrochemistry with electrolytic micelle disruption, resulting in inexpensive and customizable thin films.
A research team has developed a novel nano-micelle packaging method for delivering CRISPR/Cas9 components, allowing for efficient genome editing in the mouse brain. The optimized nano-micelles enable targeted and precise editing of genomic sequences with minimal off-target effects.
A new study uses neutron scattering to investigate casein micelles in milk, aiming to develop a better understanding of dairy products. The researcher successfully applied their model to existing data and found that even skimmed milk has complex structures at the nanoscale.
Researchers have developed a new contrast agent that detects brain metastases in certain types of cancer, such as breast cancer, at an early stage using minimal amounts of contrast agent. The agent works by detecting the formation of new blood vessels, improving MRI sensitivity and visualization.
Researchers at USC Viterbi's Department of Biomedical Engineering have developed a nanoparticle that lights up calcification, allowing for more effective detection of blocked arteries. This innovation has the potential to improve cardiovascular disease diagnosis and treatment by identifying unstable calcifications.
Researchers at the University of Würzburg have discovered how increasing amounts of active ingredients in polymeric micelles reduce their dissolution and solubility. The study aims to improve drug delivery systems by understanding molecular interactions and potential structural changes to enhance absorption and dissolving capabilities.
Scientists have discovered that skin creams contain micelles and are self-preserving, contrary to the long-held textbook picture. The study uses X-ray and neutron scattering techniques to analyze cream structure and finds co-surfactants in lamellar layers as predicted but surfactant not present.
Researchers developed a new method to use rare and expensive catalysts sparingly by encasing precious metal salts in micelles. The process efficiently catalyzes oxygen reduction in fuel cells, outperforming traditional methods.
Researchers have discovered parameters governing drug encapsulation, giving more control over the slow release of drugs in patients. This breakthrough enables fewer trial-and-error experiments in drug design, reducing side effects and facilitating personalized therapeutic treatments.
Researchers from Kumamoto University and Tokyo Institute of Technology developed a method to dissolve water-insoluble nanographene in water using molecular containers. The method successfully produced a highly ordered 2D molecular adlayer on a gold substrate, revealing its potential for next-generation functional nanomaterials.
Researchers have unraveled the complex process of how black widow spiders transform proteins into steel-strength fibers. They found that spider silk proteins form hierarchical nano-assemblies, potentially required for creating strong fibers.
Scientists have developed a new approach to cancer therapy by combining two synergistic drug components into a dimer, which can be loaded into polymeric nanotransporters at exceptionally high concentration. This method reduces side effects and improves transport and accumulation of drugs in tumors.
Scientists have developed a novel TEM technique that captures dynamic reactions at the nanoscale, allowing researchers to study material transformations in real-time. This breakthrough enables better control over nanoscale properties and has significant implications for designing materials with desired properties.
Researchers from Okinawa Institute of Science and Technology Graduate University developed a method to create ordered crystal-like structures from micelles using shear flow, enabling faster drug discovery and material sciences applications. The technique involves adding external shear flow to induce controlled crystallization at ambien...
Researchers discovered a new mechanism for incorporating soft biological matter into calcium carbonate crystals, creating strong biominerals. The study provides insight into the formation of natural minerals with composite properties, which could lead to sustainable energy materials.
A novel method of altering a protein in milk has been discovered, enabling the delivery of an antiretroviral drug to infants with HIV/AIDS. This breakthrough could greatly improve treatment for the estimated 3.4 million children suffering from the disease.
Researchers aim to re-shape nanoemulsion-based delivery systems to increase absorption of nutraceuticals like flavonoids and carotenoids in the gastrointestinal tract. The goal is to improve bioavailability, potentially offering health benefits such as anti-inflammatory or anti-cancer effects.
A team of scientists has developed a new face paint that protects soldiers' faces from the intense heat generated by bomb blasts, while also providing camouflage. The makeup can shield skin for up to 15 seconds before temperature rises to cause burns.
A new class of nanoparticles has been developed to prevent premature drug release and ensure targeted delivery to tumors. The dual-responsive boronate cross-linked micelles (BCMs) can release drugs in response to acidic environments or mannitol, minimizing premature release and maximizing tumor targeting.
Researchers have invented fluorescent nano-particles that can continuously change colors to track molecules under a microscope. The color-changing particles, made with quantum dots, can be tailored to tag specific molecules and provide insights into biological processes.
Researchers developed biodegradable tooth-binding micelles that effectively bind to teeth and inhibit the growth of Streptococcus mutans, a primary cause of tooth decay. These micelles showed promising results in reducing biofilm formation on hydroxyapatite particles.
Researchers at City College of New York create amphiphilic molecule that forms self-assembled structure responding to temperature changes, resembling nature's own adaptation mechanisms. The discovery opens doors for designing adaptive soft materials that can take cues from nature.
Purdue researchers have discovered a new approach for repairing damaged nerve fibers in spinal cord injuries using copolymer micelles, which not only deliver drugs but also directly repair axons. The treatment boosts axon recovery from 18% to 60%, showing promising results for treating spinal cord injuries.
Researchers at UC Santa Barbara and the Burnham Institute for Medical Research have created a nanoparticle that can detect and attack plaque in arteries, a leading cause of cardiovascular disease. The treatment shows promise for developing therapies to prevent heart attacks and strokes.
Scientists at NIST have developed a new technique using terahertz spectroscopy to study biomolecules in water. The method uses nanoscale droplets of soap-like molecules called micelles, which provide an aqueous environment for the biomolecules to flex and bend while limiting water absorption.
Researchers at Rice University have discovered a novel method for assembling gold and silver nanoparticle building blocks into larger structures, inspired by the self-assembly of lipid membranes that surround every living cell. The new technique allows for the creation of ultra-potent cancer drugs and efficient catalysts.
Researchers discovered that surfactant micelles assemble into specific structures on a graphite surface due to van der Waals interactions, overcoming Brownian motion. The dynamic nature of these micelle structures opens new horizons for exploration and potential technological applications.