Articles tagged with Illumination Microscopy
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
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Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
The ERC Consolidator Grant will support advanced microscopy and spectroscopic analysis to examine bacteria's interaction with light, potentially leading to new imaging technologies. This research may inspire Living Photonic Circuits where organelles control and guide light paths within living cells.
Elizabeth Hillman, a pioneer in imaging method development, is leading the new Department of Imaging Sciences at St. Jude Children's Research Hospital. The department aims to develop innovative new imaging and measurement approaches that will enable groundbreaking scientific studies and improve patient care.
Researchers developed a new technique to view living mammalian cells using ultrafast pulses of illumination from a soft X-ray free electron laser. The microscope captured images of carbon-based structures in living cells with high spatial resolution and a wide field of view, revealing new insights into cellular biology.
A new open-top light-sheet microscope with swept illumination enhances the technique for nondestructive 3D pathology. The improved design quadruples the field of view and doubles optical sectioning ability, making it suitable for analyzing complex tissue structures.
A team of researchers at the University of Connecticut created freeform illuminators that enable flexible illumination design and calibration using a blood-coated sensor. The newly developed technology simplifies microscopy experiments by reducing size, increasing density, and adjusting angle of illumination.
Researchers have successfully applied speckle illumination to photoacoustic microscopy, reducing tissue damage and improving image reconstruction. The technique harnesses the power of structured illumination methods initially developed for optical microscopy, allowing for more efficient imaging with acoustic detection.
Researchers develop hybrid brightfield-darkfield transport of intensity approach, expanding accessible sample spatial frequencies and achieving 5-fold resolution increase. This method enables precise detection and quantitative analysis of subcellular features in large-scale cell studies.
Researchers developed a high-resolution holographic endoscope system that can reconstruct microscopic images without attaching equipment to the fiber bundle. The new endoscope has a diameter of 350 μm and achieves spatial resolution of 850 nm, far smaller than the core size of optical fibers.
A newly developed polarizer-embedded metalens microscope system achieves high-quality, wide-field imaging with a large depth-of-field, significantly expanding human eyesight to the microworld. The chip-scale device offers a thousand-fold reduction in volume and weight compared to traditional microscopes.
A new microscope allows for real-time aberration-free dynamic speckle microscopy using compressed time-reversal matrix technology. This enables almost real-time volumetric adaptive optical imaging with reduced data acquisition time and improved lateral resolution.
Researchers develop chip-compatible 3D nanoscopy that surpasses the Abbe diffraction limit using a broadly-tunable large-spatial-frequency-shift effect. This method offers advantages over existing superresolution techniques, including high stability, low cost, and integration with microfluidic and optoelectronic functional chips.
The article reviews the development of surgical microscopes, from their introduction in 1921 to the latest advancements. Advanced technologies such as augmented reality displays, hyperspectral imaging, and robotic visualization platforms are increasing the capabilities of surgical microscopes. These improvements enable better visualiza...
Researchers developed an adaptive microscope that can analyze and optimize its settings in real-time, achieving five-fold improvements in resolution. This technology enables long-term imaging of entire embryos and has significant implications for high-throughput drug screens and biological modeling.
Researchers have developed two new microscopes that capture fast-moving cells in 3-D and reduce light exposure to preserve cell health. The iSIM microscope enables real-time super resolution imaging of small structures at high speed.
The new Multi-View SPIM microscope allows scientists to image rapid biological processes in thick samples at high resolution. It can record the movements of every nucleus in the embryo throughout its life, providing valuable insights into embryonic development.
The new microscope allows researchers to study the dynamic inner lives of living cells without damaging them. It uses a combination of structured illumination and two-photon microscopy to create high-resolution, three-dimensional images of cellular landmarks.
Scientists have developed a deconvolution algorithm that improves the resolution of Single Plane Illumination Microscope (SPIM) images. This advancement provides new opportunities for studying sub-cellular processes in large living specimens.
A new NIH grant will use electrical engineering concepts to profile host-virus interactions and identify immune responses. The study aims to develop a quantitative method to analyze the interaction between viruses and host cells, potentially leading to faster diagnosis and treatment of viral infections.