Researchers at Texas A&M University develop a laser technique called TRIP to directly measure quantum forces shaping proteins, enabling accurate prediction of how pharmaceutical drugs interact with them. This breakthrough could lead to the design of medicines tailored to specific diseases, revolutionizing precision medicine.
Researchers at Purdue University have developed a next-generation technology platform designed to dramatically accelerate one of the slowest stages of cancer drug discovery. The platform combines chemical synthesis, biological testing, and mass spectrometry into a single integrated workflow, allowing researchers to generate, evaluate, ...
Researchers created a powerful catalyst from renewable lignin waste, boosting the efficiency and stability of oxygen evolution reaction in water electrolysis. The new catalyst achieves a low overpotential of 250 mV at 10 mA cm² and maintains strong performance for over 50 hours.
Wiley has expanded its spectral libraries with major updates to IR, Raman, and LC-MS collections, delivering researchers enhanced capabilities for faster and more confident compound identification. The expansion brings over 9.5 million high-quality spectra, including 1 million IR spectra and 161,000 Raman spectra.
Researchers at the University of Graz and the University of California, San Diego have developed a novel method to determine omega positions of lipids in complex biological samples. This breakthrough enables the study of biological mechanisms in unprecedented detail, particularly for inflammation-related diseases.
Researchers developed t-SPESI technology to visualize cell parts and analyze lipid distributions in complex biological samples. This enables the detection of abnormal lipids linked to disease, advancing therapies and diagnostic techniques.
A new mass spectrometry technique from Brown University dramatically reduces sample loss, paving the way for more accurate and efficient protein analysis. The nanopore ion source transfers ions directly into the vacuum of a mass spectrometer, eliminating the need for drying and vacuum processes.
Researchers have developed new methods to analyze dry-coated drug particles using 3D Raman mapping, which can effectively slow down dissolution rates. Another study introduces a novel technique for detecting complex traditional Chinese medicines, preventing adulteration and counterfeiting.
Researchers have developed a tiny spray of liquid that forms a merged, femtolitre-size Taylor cone, allowing them to study fast biochemical reactions. The device, called dual nano-electrospray, enables scientists to probe solution interactions and complex biomolecules with unprecedented precision.