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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Patient treatment shows: brain pacemaker helps with stuttering

A new pilot project by Frankfurt University Medicine and Münster University Hospital has shown that deep brain stimulation can significantly reduce stuttering frequency and severity. The treatment, which involves implanting a thin wire into the left thalamus of the brain, was found to decrease stuttering by 46% in one patient.

‘Life-changing’ genetic link offers hope for millions who stutter

A global study identified DNA markers for stuttering, providing a genetic link that will allow clinicians to predict which family members will experience the speech disorder. The research also found a link between stuttering and neurodiversity, emotional regulation, and musical rhythm.

Large-scale study uncovers 57 genetic hotspots into stuttering origins

A large-scale study analyzing over 1 million individuals has identified 57 distinct genomic regions associated with 48 genes linked to stuttering. The findings suggest a shared genetic architecture with autism, depression, and musicality, providing a foundation for early identification and therapeutic advances in stuttering.

Large-scale study defines genetic architecture of stuttering

A large-scale study has identified 48 genes linked to stuttering, shedding light on the neurological pathways of risk. The findings suggest a shared genetic basis with autism, depression, and musicality, providing a foundation for future research.

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Researchers have located the brain network responsible for stuttering

A study led by the University of Turku has identified the brain network responsible for stuttering, which may lead to effective treatments. The research found that stuttering is associated with structural changes in a specific brain network involving the putamen, amygdala, and claustrum.

How our brains' beta waves predict stuttering

A team of researchers from New York University recruited 30 stutterers and monitored their brain activity using magnetoencephalography (MEG) while they spoke. The study found increased beta waves associated with cues that preceded stuttered words, suggesting a predictive link between brain activity and stuttering.

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Gene discoveries give new hope to people who stutter

Researchers have discovered new genetic variations associated with developmental stuttering, offering new therapeutic directions to improve outcomes. The study found that stuttering is polygenic, meaning multiple genetic factors contribute to and protect against the condition.

Stuttering starts at speech initiation, not due to impaired motor skills #ASA181

A new theory suggests that stuttering is caused by anomalies in the brain's initiation circuit, which chooses a word to speak. This circuit is separate from the muscle-coordinating circuit, and its impairment leads to stuttering. Researchers believe this could lead to targeted treatments for stuttering with fewer side effects.

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Star-shaped brain cells may be linked to stuttering

A UC Riverside-led study found that treatment with the medication risperidone leads to increased activity of astrocytes in persons who stutter. This increase in activity may help reduce stuttering by blocking dopamine receptors in the striatum.

What birdsong tells us about brain cells and learning

Researchers at UChicago study birdsong to understand brain cell properties and their role in learning, revealing surprising similarities with human stuttering. The study uses zebra finch neurons to show that changes in intrinsic cell properties are closely tied to song patterns and stuttering behavior.

Ecopipam reduces stuttering symptoms in proof-of-concept trial

A proof-of-concept trial found ecopipam significantly reduced stuttering symptoms, including increased speech fluency and faster reading completion. The medication was well-tolerated, with no serious adverse effects or signals of weight gain or abnormal movement disorders.

NIH study in mice identifies type of brain cell involved in stuttering

A recent NIH study using a mouse model of stuttering identified the loss of astrocytes as a critical brain cell type involved in the disorder. The research found that this loss was most prominent in the corpus callosum, a part of the brain that bridges the two hemispheres. This discovery could lead to novel interventions for stuttering...

Global study investigates the cause of stuttering

Researchers are searching for genetic links to stuttering through a global study recruiting Australian stutterers aged seven and older. The study aims to develop treatments targeting the disorder's underlying cause, rather than just symptoms, with potential benefits for better treatment and prevention of stuttering.

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Stuttering: Stop signals in the brain prevent fluent speech

A hyperactive network in the right frontal part of the brain plays a crucial role in stuttering by inhibiting speech movement planning and execution. The more severe the stuttering, the stronger the connections between brain regions involved in neural inhibition of speech movements.

Stuttering: Stop signals in the brain disturb speech flow

Research at the Max Planck Institute for Human Cognitive and Brain Sciences reveals that hyperactivity in the right hemisphere of the brain is central to stuttering. The study found a stronger connection between brain regions involved in speech movements, leading to impaired fluency.

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Stuttering related to brain circuits that control speech production

Researchers found neuro-metabolite alterations across the brain linking stuttering to changes in brain circuits that control speech production and circuits supporting attention and emotion. Disturbances in neuronal or membrane metabolism contribute to the development of stuttering.

Mouse pups with human mutation show signs of stuttering

A study in mice reveals changes in ultrasonic vocalizations consistent with stuttering in humans, suggesting a potential understanding and treatment for millions affected. The findings provide an experimentally tractable animal model for aspects of stuttering research.

ISTAR researchers, clients turn to video to treat stuttering

A pilot study by researchers at ISTAR found that video self-modelling (VSM) helps reduce stuttering frequency in adults who experienced relapse after therapy. Participants watched videos of themselves speaking fluently, with improved results for those viewing their videos regularly.

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Stuttering linked to rhythm perception deficiency

Researchers at Michigan State University found that children who stutter have difficulty perceiving a beat in music-like rhythms, which may account for their halting speech patterns. This study has implications for treating stuttering and suggests that improving beat perception in children could lead to improved fluency in speech.

Brain develops abnormally over lifespan of people who stutter

Researchers found abnormal development of grey matter in Broca's area, the region responsible for speech, persisting into adulthood in children who stutter. The study used MRI imaging to examine brain development in both children and adults, finding a steady decline in cortical thickness not observed in people who stutter.

Brain development differs in children who stutter

A study by University of Alberta researcher Deryk Beal found that children who stutter have less grey matter in brain regions responsible for speech production. This discovery highlights the importance of early treatment approaches like those pioneered by the Institute for Stuttering Treatment and Research.

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Breastfeeding may protect against persistent stuttering

A recent study found that children who were breastfed had a higher likelihood of recovering from stuttering and returning to fluent speech. The researchers suggest that essential fatty acids found in breast milk may play an important role in brain development and language skills.

Do songbirds hold key to stuttering?

Researchers at Michigan State University investigate the brain and behavior of zebra finches to understand the relationship between rhythm and stuttering. The study aims to identify which parts of the brain are responsible for processing rhythm, with potential implications for treating stuttering in children.

Giving a voice to kids with Down syndrome

A new case study by the University of Alberta's ISTAR Institute shows that fluency shaping can significantly improve a child's speech in individuals with Down syndrome who stutter. Four months of treatment led to a 98.6% improvement in Sarah's fluency, enabling her to function better socially and academically.

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Surprising pathway implicated in stuttering

A new study found that mutations in a gene called NAGPA, which affects lysosomal function, are associated with persistent stuttering. The research provides evidence that impairment in cellular recycling centers may play a role in causing some people to stutter.

Research looks at stuttering differences in boys, girls

A recent study aims to identify neural reasons for early childhood stuttering, with a focus on sex differences that influence recovery rates. The research seeks to better understand the causes of this speech disorder, which affects about 5% of children during early stages of speech acquisition.

Researchers discover first genes for stuttering

A study has identified three genes associated with stuttering in volunteers from Pakistan, the US, and England. Mutations in these genes have been linked to other metabolic disorders, suggesting a possible inherited component to stuttering.

Is stuttering in our DNA?

A recent study has found strong evidence for a genetic component in stuttering, with the likelihood of spontaneous recovery linked to genetic factors. Researchers hope that identifying specific genes underlying stuttering will lead to improved clinical decisions and treatments.

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Bilingual children more likely to stutter

Research published in Archives of Disease in Childhood suggests that bilingual children are significantly more likely to stutter and find it harder to lose their impediment than monolingual children. Children who exclusively spoke one language before the age of 5 had a higher recovery rate from stuttering by the age of 12.

Helping children handle stress, emotions may help stuttering

A new study by Vanderbilt University researchers suggests that helping children handle stress and emotions may help alleviate stuttering. The study found that children who stutter are more likely to be emotionally aroused in everyday situations, have difficulty controlling their attention, and take longer to calm down.

Stuttering more than talk - research shows brain's role in disorder

Researchers at Purdue University found that adults who stutter process language differently than those who don't, even when not speaking. The study, published in August, measured brain electrical activity and response time to find complex interactions between language and motor systems.

DAF most helpful for stutterers with atypical auditory anatomy

A study of 14 adults with persistent developmental stuttering found that DAF was more effective for those with atypical auditory anatomy. The research also identified two subgroups: one with rightward planum temporale asymmetry who showed improved fluency, and another with leftward planum temporale asymmetry who did not respond to DAF.

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Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

Mechanism behind stuttering revealed

A study has identified a significant difference in brain tissue structure between individuals with persistent developmental stuttering and those with normal speech. The abnormality may develop during early language and speech acquisition, explaining how disturbed signal transmission affects speech production.

Multimillion-dollar grant to fund more research into speech disorder

A new $4 million grant from the NIH will explore four sets of factors contributing to childhood stuttering, including language function, epidemiology, motor/physiological functions, and psychological factors. Researchers hope to identify risk factors and predictors for recovery.

Study ties stuttering to anatomical differences in the brain

A study found that adults with persistent developmental stuttering (PDS) have significantly larger right and left temporal lobes, and more irregularities in brain shape compared to controls. Sex and writing hand preference were also linked to anatomic features.

Intensive Stuttering Program Aims At Coping Not Cure

The program, now in its second year, provides four weeks of intensive speech therapy for adults aged 20-50. Participants learn skills and behaviors to overcome stuttering, such as awareness, acceptance, and preparatory techniques like rehearsal and prevoicing. The goal is to improve communication flow and reduce stuttering interruptions.

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