Articles tagged with Cost Effectiveness
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A single dose of IV iron dextran is the most cost-effective treatment option for women with heavy menstrual bleeding and iron deficiency anemia. The study found that IV iron dextran improves quality of life and reduces costs compared to oral ferrous sulfate.
A study found cryopreserved platelets to be a cost-effective option for managing surgical bleeding in cardiac surgery, dominating liquid-stored platelets in this setting. Further investigation is required to assess the economic benefits of cryopreserved platelets in broader populations.
A new study suggests that long-acting injectable treatment can prevent up to 160 infant infections per year in Zimbabwe. The treatment, LA cabotegravir with rilpivirine, could be cost-effective if priced at $156/year or lower for women whose HIV has not been fully suppressed at delivery.
Biomedical researchers recommend diversifying funding sources, pursuing earlier licensing and commercialization, and fostering international collaborations. The US drug discovery landscape is at risk due to federal funding cuts, and alternative approaches are needed to ensure continued progress.
A new study from the University of Lübeck introduces a 'lottery-first' approach to research grant allocation, increasing female representation by 10% and funded projects led by women by 23%. This method reduces estimated economic costs by two-thirds while maintaining scientific excellence.
Provincial partnerships with corporate-provided virtual care programs raise concerns about access, quality of care, and data privacy. Governments must ensure healthcare standards are met, protect patient data, and maintain transparency around contracts and profits. The authors advise caution before introducing corporate entities in the...
Automated external defibrillators (AEDs) in private homes show effectiveness in improving patient outcomes for those with shockable rhythms during cardiac arrest. However, considering the rarity of cardiac arrest at home and current AED pricing, general purchase is not deemed cost-effective.
This study found that GLP-1RAs and SGLT2is offer the greatest cardiovascular benefits for adults with type 2 diabetes. The magnitude of benefit depends on baseline age, atherosclerotic cardiovascular disease, heart failure, and kidney impairment.
A study found that tirzepatide is more cost-effective than semaglutide for treating knee osteoarthritis and obesity. Tirzepatide offered a more favorable return on investment, making it the better choice for patients.
A UCLA Health study found that taking an 8-strain probiotic daily reduces the risk of pouchitis, a common inflammatory condition. However, the treatment's cost-effectiveness depends on the patient's likelihood of flare-ups, with benefits only seen in patients with frequent relapses.
A simulation study by Mass General Brigham researchers found that intensive blood pressure control is cost-effective, even with typical levels of measurement error. The study suggests that targeting systolic blood pressure below 120mmHg prevents more cardiovascular events than lower targets.
A new study by Michigan Medicine University of Michigan researchers concludes that broad COVID-19 vaccination in adults saves the US more money than it spends, with significant economic benefits for those over 65 and middle-aged adults. The model focuses on preventing deaths, hospitalizations, and lost productivity.
A modeling study finds that COVID-19 vaccination is more cost-effective for individuals aged 65 and above, with favorable results across different parameter input scenarios. The study's findings support the Advisory Committee on Immunization Practices' decision to recommend vaccination with the 2023-2024 mRNA vaccines.
A new analysis suggests that preventive mastectomy is a cost-effective way to reduce the likelihood of developing breast cancer compared to breast screening and medication. Women aged 30 or above with a lifetime breast cancer risk of 35% or more may benefit from this treatment option.
Cessation of public water fluoridation would lead to higher rates of tooth decay and increased healthcare costs in the US. The model suggests that current safe levels of fluoride have substantial ongoing benefits.
A randomized clinical trial found that over-the-counter and audiologist-assisted services yielded similar outcomes to prescription hearing aids. High-end and low-end hearing aids showed comparable results, challenging the need for higher-cost high-end models.
Research finds that multitarget stool DNA tests have higher sensitivity than FIT, but are not as cost-effective for early detection of colorectal cancer. Costs per detected advanced neoplasia case or early-detected CRC case are 7- to 9-fold higher for MSDT-based and N-G MSDT-based screening.
Sandia National Laboratories has achieved over $439 million in savings for the Department of Energy by streamlining purchasing agreements and securing volume pricing. The Supply Chain Management Center, created in 2006, facilitates collaboration between prime contractors to reduce costs and improve efficiency.
A long-term study published in BMJ Quality & Safety found that employing too few permanent nurses on hospital wards is linked to longer inpatient stays, readmissions, patient deaths, and ultimately costs more. Redressing the balance saves around £5000 for each year of healthy life gained, but not if temporary agency staff are used.
Biomass is crucial for Europe's ability to reach its climate targets, providing both energy and negative emissions. Excluding biomass from the European energy system would increase costs by 169 billion Euros per year.
A randomized clinical trial found no association between immediate skin-to-skin contact and improved neurodevelopmental outcomes in very preterm neonates. However, the intervention was shown to enhance breastfeeding practices up to 12 months compared to standard care.
A new study reveals that the US national vaccine strategy saved more money than it spent on testing, buying and delivering COVID-19 vaccines after just one year. The analysis found that the vaccines reduced serious illness and deaths, resulting in significant cost savings.
Tulane University scientists developed a handheld device to deliver rapid and accurate tuberculosis diagnoses in under an hour. The device, called the lab-in-tube assay (LIT), can detect Mycobacterium tuberculosis DNA in saliva, blood, and sputum samples, offering a cost-effective tool for improving TB diagnoses in resource-limited areas.
A new study from the University of Massachusetts Amherst found that co-undergrounding wires, particularly in outage-prone areas, can pay off with a cost savings of nearly 40% compared to replacing them separately. The study suggests that proactively undergrounding lines that are currently above ground can bring significant benefits.
Researchers at the University of Surrey developed a cost-effective method for removing CO2 from the air and converting it into synthetic fuel. The Dual-Function Material (DFM) process has been shown to be financially competitive with established industry methods, offering a promising route to decarbonize industries.
Tirzepatide and semaglutide offer substantial long-term health benefits in US adults, reducing obesity risk. However, the high costs of these medications make them not cost-effective at current net prices, hindering equitable access.
A new study from Colorado State University found that fortified corrals can reduce livestock losses due to predator attacks on nearby carnivores. The study demonstrated a beneficial spillover effect where households neighboring those with chain-link corrals also reported fewer attacks on their livestock.
A new study introduces Aloe vera as a natural scaffold for cultured meat production, enhancing the taste and texture of alternative proteins. The research also highlights a novel bioprocessing approach using Aloe vera scaffolds in a macrofluidic single-use bioreactor.
Researchers at the University of Houston have developed a new membrane that allows water to flow eight times faster while maintaining high salt rejection rates. This breakthrough could lead to more efficient and cost-effective desalination systems, lowering costs and increasing access to clean water.
A new home-based intervention has been shown to reduce unplanned hospital admissions among older adults with mild frailty by 35%. The service, which includes personalized visits and tailored support, also leads to small improvements in wellbeing and reduces hospital costs.
A new remotely-delivered support programme, NIDUS-Family, has been shown to improve the lives of people with dementia while reducing healthcare costs. The programme uses goal setting and personalized care to help individuals live well at home for longer, resulting in cost savings of £8934 per person over one year.
A cluster trial found salt substitution to be safe, with significant reductions in stroke recurrence and death rates among patients. The study supports large-scale implementation of this low-cost intervention as a major public health gain.
Researchers developed a novel microscopy technique to study metabolic changes in individual cancer cells at the single-cell level. They found that radiation treatment caused significant metabolic shifts in head and neck squamous cell carcinoma cells, particularly through the activation of HIF-1α.
Researchers found that short-course antibiotics can be as effective as traditional longer treatments in preventing death and recurrence of pneumonia. This approach offers significant value for healthcare systems by reducing hospital expenditure while maintaining excellent patient outcomes.
The University of Texas at Arlington is developing more efficient processes for sourcing rare earth elements needed to produce high-performance magnets. The project aims to make the mining of these critical materials more environmentally sustainable and cost-effective.
Researchers analyzed cost-effectiveness of semaglutide for non-diabetic overweight/obese individuals with heart disease. With price reductions, semaglutide shows promise in reducing lifetime costs and improving health outcomes.
A polypill containing a statin and three half-standard dose antihypertensives could significantly reduce health disparities in low-income, majority Black populations with limited access to healthcare. The study suggests that this treatment approach may be a high-value intervention for preventing cardiovascular disease.
Early detection of breast cancer can lead to less intensive treatments, saving the Canadian healthcare system $459.6M over women's lifetimes and 3,499 breast cancer deaths. Screening mammograms and diagnostics costs are easily offset by earlier stage treatment.
The authors introduce advanced methodologies for integrating maintenance strategies and structural health monitoring to extend infrastructure service life. Topics include data-driven decision-making, multi-objective optimization, cost-benefit analysis, and the role of data analytics in managing uncertainties.
A team of researchers from DTU has successfully produced vitamin B2 using a novel, cost-effective, and climate-friendly method involving food-approved lactic acid bacteria. The production process requires only basic fermentation tools and can be integrated into traditional foods, enhancing public health and reducing environmental impact.
A new study suggests that using AI-ECG tools to screen patients for low ejection fraction is cost-effective in the long term, especially in outpatient settings. The study found a cost-effectiveness ratio of $1,651 per quality-adjusted life year, indicating that the program can reduce costs over time.
A study published in the Journal of the American College of Surgeons found that using antibiotics alone to treat children with uncomplicated appendicitis is a cost-effective and safe alternative to surgery. This approach resulted in lower costs and similar quality-of-life scores compared to upfront surgery.
The American Heart Association and Arizona Cardinals partnered with 12 local schools for CPR and AED training, aiming to improve cardiac emergency outcomes. The training equipped schools with lifesaving skills and resources, increasing the community's capacity to respond in cardiac emergencies.
Greg Liu has developed a revolutionary way to convert certain plastics into soaps, detergents, lubricants, and other products through thermolysis. The process breaks down polypropylene and polyethylene molecules into chemical compounds, leaving minimal residual solids and usable oil.
Researchers have developed a deep-learning-powered metalens imaging system that overcomes limitations of traditional metalenses. The system pairs a mass-produced metalens with an image restoration framework driven by AI to achieve aberration-free, full-color images while maintaining compact form factor.
Researchers at Kumamoto University have developed a cutting-edge diagnostic tool, Intelli-OVI, to rapidly identify emerging SARS-CoV-2 variants. This system combines advanced DNA detection technology with computational algorithms to offer a quicker and more cost-effective method of monitoring viral mutations.
A new study found that simple kitchen improvements can significantly reduce exposure to harmful pollutants, preventing over 67,000 premature deaths annually. Widespread implementation of ventilation systems could be an affordable solution to mitigate household air pollution in rural areas.
Upgrading home insulation can lower medical bills and extend healthy lives by reducing blood pressure and CVD risk. Simulations showed that upgrading or retrofitting insulation is cost-effective for many homeowners, with significant health benefits justifying the costs.
Researchers analyzed a thermophotovoltaic system paired with phase-change materials for energy storage and found slight reductions in costs. The study identified key factors affecting TPV system costs, highlighting the need for future research to improve adoption and efficiency.
Researchers found that restoring coastal marshes can significantly help protect coastlines at a reasonable cost. A study by MIT graduate student Ernie I. H. Lee and professor Heidi Nepf shows that enhancing salt marshes in front of protective seawalls can reduce construction costs while still providing adequate protection from storms.
Two studies found that bariatric surgery is more cost-effective in the long term compared to GLP-1 RA weight loss drugs alone. Combining both treatments is even more cost-effective. The use of GLP-1 RA before surgery appears safe and may be a novel approach to treating obesity.
The Lancet Commission on Investing in Health recommends focusing on 15 priority health conditions to achieve a 50% reduction in premature deaths. Raising taxes on tobacco is key, with estimates suggesting it could reduce mortality rates by more than any other single policy.
A new report argues that countries can cut premature mortality in half by 2050 through targeted health investments. By prioritizing the 15 health conditions causing most premature deaths and implementing public subsidies for essential medicines and diagnostics, nations can achieve this goal.
Researchers developed a model to project Italy's energy storage needs for a renewable energy system, accounting for daily and seasonal fluctuations. The model suggests that increasing short-term energy storage capacity is critical for decarbonizing the power sector.
A research team has developed a simplified synthesis method for organic fluorophores using formaldehyde, reducing molecular size and increasing atomic efficiency. The new technique can also be applied to in vivo environments, showing promise for life sciences research and diagnostics applications.
A new study identifies multiple technologies to cost-effectively decarbonize the energy system, prioritizing their adoption and transition. The findings suggest a range of options to achieve near-cost-optimal futures, emphasizing research and development investments.
A new study found that RSV vaccination programs targeting older adults with underlying health conditions are more likely to be cost-effective than general age-based strategies. Vaccinating people aged 70 years and older with chronic medical conditions is likely to be cost-effective based on commonly used cost-effectiveness thresholds.
A novel method for the selective chemical recycling of PET has been developed, allowing for the recovery of polyester from textile waste. The method uses alcohols and an inexpensive iron trichloride catalyst to yield diethyl terephthalate and ethylene glycol with high selectivity.
Researchers have developed a cost-effective and easily reproducible point-of-care testing device that can accurately measure cortisol levels in the blood. The device uses iridium oxide nanoparticles to improve stability, sensitivity, and selectivity, allowing for commercial use.
A novel AI tool has been shown to accurately estimate gestational age from blind ultrasound sweeps, comparable to expert sonographers. The technology has the potential to democratize prenatal care in resource-limited settings by expanding access to quality diagnostic tools without the need for expensive equipment or specialized training.