Articles tagged with Olfactory Perception
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Researchers at Penn Vet have shown that trained dogs can identify the odor of hemangiosarcoma, a malignant cancer of blood vessel cells, with an accuracy rate of 70%. Early detection could lead to better outcomes, including prevention of disease spread and earlier removal of the spleen or initiation of chemotherapy.
Researchers identified a gene that actively causes a decline in food-seeking behavior after reproduction, potentially benefiting the population by reducing competition for resources. This discovery challenges traditional views on aging and offers new insights into programmed mechanisms driving age-related decline.
James Schwob, a professor at Tufts University School of Medicine, has been named a fellow of the National Academy of Inventors. His research focuses on the mechanisms that regulate neural development using the peripheral olfactory system as an ideal model for neuroregeneration and therapeutic approach for age-related olfactory loss.
A new review emphasizes the importance of smell health, highlighting its role in nutrition, cognitive function, and psychological resilience. Researchers call for a global campaign to promote smell health through education, awareness, and targeted public health policies.
A new study found that the brain encodes molecular features of odors early on to support odor discrimination, while representing subjective attributes like pleasantness later. This distinction can be used to assess olfactory disorders or enhance function.
A parasitic ant queen tricks ant workers into killing their queen mother by spraying a foul-smelling chemical, causing her daughters to turn against her. The parasitic queen then usurps the throne and is served by the workers.
The study reveals how chemical sensors discriminate among various odorant molecules using explainable AI, enabling the selection of receptor materials for high-performance sensors. This breakthrough advances understanding of human olfaction and paves the way for practical application of artificial olfaction technology.
A cohort study found that poor olfaction is associated with a higher risk of coronary heart disease in older adults. The study suggests that assessing olfaction may be an important factor in identifying individuals at risk for cardiovascular disease.
Researchers discovered how newly created neurons rely on blood flow to migrate through the brain. The study found that blood vessels act as physical 'scaffolds' and that blood flow influences migration speed, with higher speeds seen in regions with abundant blood flow.
A study from the Champalimaud Foundation found that when fruit flies are deprived of essential amino acids, their brains upregulate two olfactory receptor genes involved in smell, leading to a refined sense of smell that guides them to protein-rich yeast and gut bacteria. This interplay between smell and taste regulates feeding behavior.
Scientists at RIKEN Center for Brain Science found that fruit flies use separate circuits to compute pleasant and unpleasant odors, challenging the idea that 'good' is the opposite of 'bad'. The discovery may contribute to a better understanding of human brain's flavor appreciation mechanisms.
A new study found that 80% of participants who reported a change in their smelling ability after COVID-19 scored low on a clinical scent-detection test two years later. Those with a history of COVID-19 may be especially at risk for hyposmia, an issue underrecognized among the general population.
Scientists discovered a unique process by which ants select a single odorant receptor from hundreds of genes, using transcriptional interference to silence downstream neighbors. This mechanism has broad implications for the study of gene regulation and sensory systems in insects.
A new study reveals that the brain integrates signals from taste and smell earlier than thought, activating the same parts of the brain's taste cortex. This overlap suggests a shared neural code for flavour experiences, which may influence our eating habits and preferences.
Research at DZNE suggests that immune response plays a significant role in Alzheimer's disease, causing olfactory dysfunctions by attacking neuronal fibers. This may enable the development of early diagnosis and treatment methods.
A large-scale genetic study found ten new regions associated with the ability to detect specific odours, with three showing sex-specific effects. The research also uncovered a link between the risk of Alzheimer's disease and the sense of smell, highlighting the interconnectedness of these senses.
Researchers trained two dogs to distinguish between sebum swabs from people with and without Parkinson's disease, achieving sensitivity of up to 80% and specificity of up to 98%. The study suggests that dogs could help develop a quick, non-invasive method for early detection.
Researchers propose using chemical sensors to diagnose bacterial infections by detecting volatile organic compounds in bodily fluids, providing a rapid and affordable diagnostic test. The technology has the potential to improve treatment plans and combat antibiotic resistance.
Scientists at Tufts University have developed a three-dimensional model to study the regeneration of nerve tissue in the nose, revealing that dormant stem cells play a key role in preserving the sense of smell. The research found that these stem cells actively support the generation of new olfactory neurons.
A recent study developed a VR game that combines olfactory stimulation with immersive gameplay to improve cognitive function in older adults. After just 20 minutes of play, participants showed significant improvements in visuospatial rotation and memory tasks.
A study by the University of Eastern Finland reveals that traffic-derived ultrafine particles influence gene regulation in human olfactory mucosa cells, particularly affecting the PI3K/AKT signaling pathway. The findings suggest a potential link between air pollution and neurodegenerative diseases.
The AChemS 47th Annual Meeting features cutting-edge research on chemosensory perception, including taste and smell dysfunction in cancer patients and potential associations with learning and memory decline. The conference also highlights the impact of GLP-1 Receptor Agonists on human taste ability.
A study on heterosexual women found that personal scent preferences predicted how much they liked their interaction partners after four-minute chats. The researchers discovered that the quality of the in-person interaction influenced how participants perceived someone's smell.
A new brain imaging study found that age and brain shape significantly impact the strength of connections between olfactory brain regions in dogs. Younger dogs and those with elongated brains had stronger functional connectivities, while older dogs and rounder-headed individuals performed worse in smell tests.
Researchers at the University of Florida have discovered a vitamin D nasal spray that significantly reduces nasal inflammation and improves sense of smell in mice. This study suggests a new potential treatment for humans suffering from loss of smell due to inflammation, which is often caused by cigarette smoke or COVID-19.
A study found that alcohol consumption boosts the production of sex pheromones in male fruit flies, increasing their attractiveness to females and mating success. This effect is mediated by three neural circuits that balance attraction and aversion to avoid intoxication.
Scientists successfully fermented miso on the International Space Station, discovering differences in bacterial communities and flavor profiles compared to Earth-made miso. The study's findings suggest that food fermentation can thrive in space, opening up new possibilities for astronaut well-being and performance.
Mass General Brigham researchers developed an olfactory test, where participants sniff odor labels on a card, to assess cognitive impairment. The test showed promise as a tool for identifying risk of cognitive decline and was found to be successful at home.
Despite severe sleep deficits, insomniac fruit fly mutants exhibit enhanced memory performance through altered PKA signaling in the mushroom body. This finding suggests a complex relationship between sleep and memory functions.
A Bar-Ilan University study investigates brain activity of dogs during scent detection, unveiling crucial insights into their remarkable olfactory capabilities. The findings highlight the emotional and memory-related aspects of odor processing, particularly in the amygdala region.
Researchers have identified novel mosquito repellents with high success rates from natural sources, including food and flavoring materials. The team's machine learning-based cheminformatics approach also pinpointed pyrethroid analogs up to 100 times more effective than existing industry standards.
Researchers at Ohio State University developed an e-Taste system that uses sensors and chemical dispensers to simulate various tastes. In field testing, participants could distinguish between different sour intensities with high accuracy, paving the way for immersive virtual food experiences.
Scientists at Friedrich-Schiller-University Jena have developed data sets for the description and recording of odours, using over 1,200 test subjects to compile how people perceive, describe, and classify 74 monomolecular odour samples. The researchers aim to help solve the stimulus-percept problem in smell perception.
A new study explores whether pairing food labels with odors affects how people perceive foods and promotes healthy shopping. The researchers found that odor-paired beverages were perceived more positively, suggesting that odors can improve label perception and potentially promote healthy food choices.
Scientists at NUS Medicine have developed a novel approach using nasal bacteria to deliver therapeutic molecules directly to the brain, reducing appetite and improving glucose metabolism in preclinical studies. The engineered bacteria leverage the olfactory mucosa's unique properties to deliver medication with enhanced bioavailability.
Researchers from UCL and the University of Ljubljana conducted a systematic study on the smells of nine ancient Egyptian mummified bodies, identifying materials used in mumification and evolution of practices. The study also provides insights into how museums conserve remains and preserves their olfactory heritage.
A new study found that babies show positive responses to the smell of foods they were exposed to in the womb after birth. Newborns whose mothers had taken carrot powder capsules reacted favourably to the smell of carrot, while those whose mothers had taken kale powder capsules reacted more positively to the scent of kale.
A study by Eötvös Loránd University found that Border Collies excelled in a simple olfactory task, beating breeds like Golden Retrievers and Hungarian Vizslas. The research revealed that genetic and environmental factors influence dogs' success in scent detection, contrary to expectations.
A new study by Cold Spring Harbor Laboratory researchers explains how the brain updates associations between smells and sounds based on context. The findings suggest that a feedback loop between the olfactory cortex and olfactory bulb enables fast adaptation, allowing animals to fine-tune their motor responses accordingly.
Tobias Ackels' research reveals that mammals can differentiate between odor sources at lightning speed, using a temporal dimension to orient themselves in space. This ability is encoded in the output of the olfactory bulb and could be used for early detection of dementia.
Research using fMRI to image brain activity in sleeping infants reveals that they process odors as early as one month old. The study found that distinct odors did not trigger unique activation patterns, unlike adults. Infants also inhale more vigorously when scents are appetitive than aversive.
Researchers discovered that fruit fly Drosophila busckii can detect and thrive on toxic food sources, including dimethyldisulfide, an unpleasantly smelling sulfur compound. The fly's unique adaptations provide a valuable model for studying toxin tolerance and ecological concepts.
A new collaborative research group, the Breakthrough Consortium for Olfactory Health, was launched to drive therapeutic and technical advances in smell disorders. The consortium brings together charities, patient groups, researchers, clinicians, pharmaceutical, and diagnostic companies to establish evidence-based clinical pathways.
A recent study demonstrates how DNNs can predict fragrance profiles from essential oil chemical compositions, validating sensory evaluations. The model achieved high accuracy in predicting floral scents and showed promise for generating new and unique combinations.
Researchers at Tel Aviv University discovered the brain actively prevents learning both types of memory, leading to confusion. The brain prioritizes one type of learning over the other using a strategy to resolve conflicts.
The Monell Chemical Senses Center and A*Star SIFBI are exploring the unique sensory differences between Asian and Western populations to develop products that resonate with local consumers. They aim to create sensory testing protocols specific to Asians, transforming food and nutrition strategies for companies globally.
The 8th Digital Olfaction Society World Congress highlights groundbreaking advancements in digital olfaction, from smart necklaces to drones equipped with olfactory sensors. The event showcases innovative applications of scent digitization technologies, including virtual reality systems and e-nose devices for early disease detection.
Researchers found that confined environments influence sense of smell, while VR simulations evoke stronger emotions and aroma perceptions. The study aims to improve diets for isolated individuals by personalizing aromas.
NeuroMechFly v2 simulates how a fruit fly navigates through its environment while reacting to sights, smells, and obstacles. The model can track moving objects visually or navigate towards an odor source, while avoiding obstacles in its path, enabling researchers to study brain-body coordination and animal intelligence.
Researchers at UC Irvine have discovered a powerful link between olfactory loss and inflammation in various medical conditions, including Alzheimer's and Parkinson's diseases. Scent therapy may offer a novel approach to mitigate symptoms and prevent disease onset.
Depression alters neural circuits in the amygdala, leading to reduced activity in pleasant stimuli and increased activation in negative stimuli. This negativity bias contributes to depressive symptoms. Researchers found a potential treatment by reactivating neurons involved in positive encoding of environmental stimuli.
A new artificial 'nose' inspired by the human sense of smell can detect undiagnosed diseases, hazardous gases, and food spoilage using existing antenna technology. The sensor distinguishes between different gases with an accuracy of 96.7%, surpassing previous electronic noses in some areas.
Researchers found that human participants could distinguish between two odor compounds with just 60 millisecond delays, even if they couldn't identify the correct order. This ability supports the existence of a temporal code for odor identity.
A study published in Nature elucidates the role of individual brain neurons in human odor perception, revealing distinct neural responses to smells, images, and names. The research demonstrates that different brain regions process specific functions of olfaction, shedding light on the complex mechanisms behind human scent detection.
Researchers investigate how pollutants affect pollinators' ability to recognize flower scents and how neural circuits adapt to temperature fluctuations in organisms like the roundworm. The study focuses on understanding resilience mechanisms that enable animals to cope with environmental changes.
Researchers at the University of Birmingham used Porous Liquids to separate harmful alcohols from water mixtures, consuming up to 88% of the PL pore volume. This innovation can reduce alcohol content in drinks while retaining flavor profiles, aligning with growing consumer demand for low-alcohol beverages.
Research from Bar-Ilan University reveals RNA editing is essential for fruit flies to detect odors that warn of danger and engage in social interactions necessary for survival. The study found that flies with unedited RNA struggled with their sense of smell and social communication.
A new fluorescent imaging probe can non-invasively measure loss of smell, potentially eliminating biopsies used to diagnose anosmia. The tool targets the olfactory nerve, showing promise for diagnosing and treating smell disorders in patients.
Researchers from Eötvös Loránd University found temperature and humidity have no impact on dogs' ability to detect scents. However, indoor testing outperformed outdoor environments due to distracting stimuli. Age also plays a role, with 2-3 year old dogs exhibiting superior olfactory performance.
A study from the University of California, Berkeley, shows that nematodes react to pathogenic bacteria by destroying mitochondria to protect against iron-stealing bacteria. This protective response suggests that humans may also respond to the smell of pathogens to prepare their gut for infection.