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Research points to new therapies to lessen the severity of delusions for patients with schizophrenia

A new study suggests that volatility priors, a brain's expectations about environment unpredictability, can be modified to reduce delusion severity in schizophrenia patients. The study found that volatility priors decrease over time as delusion severity improves, making them a potential treatment target.

SourceElsevier·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·TypeExperimental study·DateAug 18, 2026

Largest ever study into cannabis use investigates risk of paranoia and poor mental health in the general population

Research from King's College London and University of Bath found that people who self-medicate with cannabis for physical or mental discomfort are more likely to develop paranoia and anxiety. The study also discovered a link between childhood trauma and increased paranoia scores, which is exacerbated by cannabis use.

SourceKing's College London·JournalBMJ Mental Health·TypeObservational study·DateAug 26, 2025

Decoding fear: KAIST identifies an affective brain circuit crucial for fear memory formation by non-nociceptive threat stimulus​

A KAIST research team has identified a key neural pathway involved in forming fear memories triggered by psychological threats. The pIC-PBN circuit processes psychological distress and drives fear memory formation, offering a significant advance in understanding how psychological distress is processed.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalScience Advances·TypeMeta-analysis·DateMay 19, 2025

Paranoia may be, in part, a visual problem

A Yale study found that individuals with greater paranoid and teleological thinking performed worse in a visual perception task, claiming one dot was chasing another when it wasn't. The findings suggest a potential link between social perception errors and psychosis, potentially leading to new diagnostic tools.

SourceYale University·JournalCommunications Psychology·DateDec 17, 2024

New study explores how young people with early-onset psychosis view substance use and interventions

A new study by Southern Methodist University's Neely Myers found that young people with early-onset psychosis are ambivalent about stopping substance use. Participants offered feedback on ways to improve care, including more information about substance use and strategies for addressing psychological and physical pain.

SourceSouthern Methodist University·JournalEarly Intervention in Psychiatry·TypeCase study·DateDec 19, 2023

Plagues of the past have a lot to tell us about current crises, according to a new study

Researchers used event system theory to analyze how past pandemics, including the Black Death, were caused by cumulative events leading up to a transformation. They found similar patterns in human behavior and societal responses, highlighting the importance of understanding historical events to address current crises.

SourceConcordia University·JournalAcademy of Management Review·TypeLiterature review·DateNov 8, 2022