Research shows that bitter taste receptors can be activated by steroid hormones, influencing physiological processes. The study found that certain hormone types, like progesterone and testosterone, activate these receptors, which may play a role in pregnancy-related taste changes or stress-induced physiological responses.
Researchers at Northwestern University discovered a hidden molecular control switch inside the protein TRPM5, which regulates taste, blood sugar control and gut health. The switch can be activated or inhibited by small molecules, unlocking new opportunities for therapeutic development.
A new review emphasizes the importance of smell health, highlighting its role in nutrition, cognitive function, and psychological resilience. Researchers call for a global campaign to promote smell health through education, awareness, and targeted public health policies.
Scientists at RIKEN Center for Brain Science found that fruit flies use separate circuits to compute pleasant and unpleasant odors, challenging the idea that 'good' is the opposite of 'bad'. The discovery may contribute to a better understanding of human brain's flavor appreciation mechanisms.
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Researchers at Korea University College of Medicine found that the c-Kit protein helps protect sweet-sensing taste cells from nerve damage, allowing them to survive and regenerate. This discovery may lead to new approaches for improving nutrition, supporting patients with taste disorders, and advancing flavor science.
Researchers found that compounds inhibiting bitter taste receptors, such as (R)-(-)-carvone, can reduce the bitter aftertaste of artificial sweeteners like saccharin and acesulfame K. This discovery has potential applications in food products to enhance palatability.
A randomized controlled trial shows that eating more or less sweet-tasting foods didn't change how much people liked sweet flavors. The study found no association between the amount of sweet foods consumed and changes in body weight or biomarkers for diabetes and cardiovascular disease.
A new study uses a fruit fly model to investigate the genetic basis of cocaine addiction. By genetically modifying bitter-sensing receptors in fruit flies, researchers found that these flies developed a preference for cocaine over sugar. This study suggests that genes involved in human cocaine addiction may also be active in fruit flies.
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A new study suggests that including pork in plant-forward diets makes meals more appealing and just as healthy, offering a higher protein quality score compared to plant-based proteins. The study found that meals with lean pork delivered significantly better results for satisfaction, satiety, and willingness to adopt post-trial.
Researchers mapped the human sweet taste receptor's 3D structure in unprecedented detail, revealing its binding pocket and shedding light on why people differ in their sensitivity to sweets. This breakthrough could lead to the discovery of new regulators to curb sugar cravings.
The AChemS 47th Annual Meeting features cutting-edge research on chemosensory perception, including taste and smell dysfunction in cancer patients and potential associations with learning and memory decline. The conference also highlights the impact of GLP-1 Receptor Agonists on human taste ability.
Researchers found that fermented pearl millet flour can replace up to 20% of whole wheat flour without affecting consumer acceptance. The study also highlights the value of simple and natural food preparation techniques to improve nutrition and flavor.
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A new study maps how specific lactic acid bacteria can reduce off-flavours and degrade anti-nutrients in plant-based dairy alternatives. Fermentation with these bacterial strains increases nutrient bioavailability and enhances product nutritional profiles.
Researchers at the University of Copenhagen create a hybrid cheese recipe combining milk and pea proteins, resulting in a product with a similar texture and taste to traditional paneer. The study demonstrates that up to 25% of milk protein can be replaced with pea protein without compromising on quality.
A global study led by the Monell Chemical Senses Center found significant variations in bitterness ratings among adults from different ancestries, suggesting personalized formulations to improve medicine taste. Genetic variants and bitter modifier effectiveness also differed across groups.
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Researchers have identified novel mosquito repellents with high success rates from natural sources, including food and flavoring materials. The team's machine learning-based cheminformatics approach also pinpointed pyrethroid analogs up to 100 times more effective than existing industry standards.
Researchers at Ohio State University developed an e-Taste system that uses sensors and chemical dispensers to simulate various tastes. In field testing, participants could distinguish between different sour intensities with high accuracy, paving the way for immersive virtual food experiences.
A new study found that babies show positive responses to the smell of foods they were exposed to in the womb after birth. Newborns whose mothers had taken carrot powder capsules reacted favourably to the smell of carrot, while those whose mothers had taken kale powder capsules reacted more positively to the scent of kale.
A study on fruit fly larvae revealed the presence of neurons with mechanoreceptors in their peripheral taste organs, allowing them to sense food texture. This discovery sheds light on the complex process of tasting texture and highlights the importance of multisensory contributions in food perception.
A new study identified a group of bitter compounds in roasted Arabica coffee that influence its taste. Genetic predisposition also plays a role, with individual variations affecting how people perceive bitterness, particularly through specific taste receptors.
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Researchers suggest that understanding the science behind umami and koku could make plant-based eating more palatable. The authors reveal that key components of umami include free glutamate and nucleotides, while koku is related to small pieces of proteins called dipeptides and tripeptides.
A team of food scientists is developing tempeh products from chickpeas and peas to offset the health risks of a Western diet. The new fermented foods may help with obesity, fatty liver, hyperlipidemia, and diabetes. Preliminary research suggests they are high in fiber and low in fat.
A study published in PLOS Biology found that individuals with and without obesity prefer high-calorie foods, regardless of their taste or texture. The researchers used a large group of healthy volunteers to compare food preferences among three groups: individuals with obesity, post-bariatric surgery patients, and non-obese controls.
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Researchers have discovered 11 probable kokumi compounds in sparkling wines, which may contribute to their rich, full-bodied taste. The study identified these compounds through a combination of computer simulations and wine tastings, paving the way for further investigation into the molecular basis of kokumi sensation in wines.
A new study from Tulane University analyzed 260 honey samples from 48 states for toxic metals, finding regional differences in contamination levels. The highest arsenic and cobalt levels were found in Pacific Northwest and Southeastern honeys, respectively, while lead was detected in Carolinas honeys.
A new study has revealed a hidden pocket inside the TAS2R14 bitter taste receptor, which can recognize and respond to a wide variety of compounds. This discovery could lead to new ways of designing medications that target these receptors, potentially helping to treat conditions like asthma and inflammation.
Researchers found that confined environments influence sense of smell, while VR simulations evoke stronger emotions and aroma perceptions. The study aims to improve diets for isolated individuals by personalizing aromas.
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A recent study published in PLOS ONE utilized TāStation to refute the glucose transport taste signaling hypothesis, showing that all sweet taste signaling occurs exclusively through the TAS1R2/TAS1R3 receptor. The research demonstrates the analytical power of TāStation in resolving complex scientific problems.
Researchers developed an efficient analysis method to precisely determine gamma-glutamyl dipeptide concentrations, enabling prediction of full-bodied cheese flavor development. The method uses ultra-high performance liquid chromatography-mass spectrometry and can analyze 60 cheese samples per day.
Researchers found that positive expectations lead to increased activity in pleasure-related brain regions, while negative expectations prime pain processing. The study suggests a dissociable impact of hedonic information, with positive expectations facilitating reward processing and negative expectations heightening anxiety.
A recent study by Washington State University researchers found that women are more inclined to purchase wine with labels featuring feminine gender cues. The study's lead author noted that winemakers may want to pay attention to the perceptions of this understudied group, which represents 59% of U.S. wine consumers.
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Researchers have successfully fermented fruit juices, including apple and passion fruit, using a SCOBY to create kombucha-like beverages with boosted antioxidant levels. The resulting drinks showed promise as an alternative to traditional kombucha, with the apple juice variant ranking high in taste testing.
Researchers discovered that sea robins' legs are covered in sensory papillae with taste receptors, allowing them to detect and uncover food. The findings reveal an ancient gene controlling leg development and sensory organ formation, shedding light on the evolution of complex traits in wild organisms.
Researchers found that blind cavefish develop more taste buds on their head and chin, particularly after 18 months of age. This adaptation is thought to be an adaptive trait, allowing the fish to better detect food sources like bat guano.
Researchers used feline taste-testers to identify flavor compounds in cat food sprays. The cats preferred sprays with proteins broken down further and containing more free amino acids, leading to more savory and fatty flavors.
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Researchers found that five human bitter taste receptor types react to both free amino acids and peptides, as well as bile acids. This suggests that bitter receptors play additional roles in human health beyond food selection.
Researchers discovered that a particular sweet chemical in vanilla and almond aromas could explain the change in perceptions, along with individual sensitivity. The study also found that spatial perception played a significant role in how people smell aromas in isolated settings.
A novel tool called BitterMasS harnesses mass spectrometry to predict bitterness without prior knowledge of chemical structures. The tool achieved remarkable precision and recall rates in internal and external tests, streamlining compound screening processes.
Researchers at UMass Amherst have developed a novel extrusion segment that can create the marbled appearance and texture of plant-based whole-cut meat products. This technology has the potential to revolutionize the plant-based meat industry, expanding its product offerings and appealing to a wider audience.
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A new study from the University of Copenhagen found that six-year-olds prefer smooth textures in their food, with a preference rate of 76% for lump-free options. Researchers suggest that this aversion may be linked to a protective mechanism against potentially poisonous foods or other dangers as children become more independent.
A team of scientists at Monell Chemical Senses Center identified a temporary, universal taste blocker that works in people. The study found that rinsing with AF-353 significantly reduced bitterness in two important medicines for chronic diseases, paving the way for improving medicine compliance in children and the elderly.
Researchers use atomic force microscopy to study mouthfeel and flavor perception, potentially leading to health-promoting products with optimal taste. The study's findings could also redefine the traditional definition of flavor, incorporating mechanical perception as an additional factor.
A study by researchers at the Leibniz Institute for Food Systems Biology has uncovered a molecular link between bitter taste receptors and gastric acid release. Bitter substances stimulate parietal cells to secrete protons, leading to acidic stomach conditions. The findings hold promise for innovative treatments of gastric diseases.
Researchers have discovered distinct ethanol-water molecular clusters that determine critical alcohol content ranges in various beverages. By controlling these clusters' transitions, manufacturers can maintain ideal taste while reducing alcohol concentration.
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The study reveals that the formation of pyramid-shaped structures around water molecules is dominant at low ethanol concentrations, but chain-like structures become more prevalent at higher temperatures. This explains why baijiu has a distinct taste at room temperature, which disappears at higher temperatures.
A recent study published in Food Quality and Preference revealed that one in eight adults enjoy intensely sour sensations. Researchers found three distinct patterns of response to sourness: a strong negative group, an intermediate group with muted drops in liking, and a strong positive group where liking increased with more sourness.
A new study suggests that incorporating seafood rich in umami, such as fish and shellfish, into vegetable dishes can boost their flavor and make them more appealing. The research uses a mathematical equation to calculate the umami content of various seafood options, finding that even small amounts can greatly enhance the taste.
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Neotame has been shown to cause previously healthy gut bacteria to become diseased and invade the gut wall, potentially leading to irritable bowel syndrome and sepsis. The study also found a breakdown of the epithelial barrier, which forms part of the gut wall.
Researchers found that objective taste dysfunction disappeared one year after COVID-19 exposure, while nearly a third of individuals experienced lasting smell loss. Infection with Alpha variants was associated with the greatest degree of smell loss, highlighting a potential link between variant types and symptom severity.
Researchers at UNC School of Medicine discovered the detailed protein structure of the TAS2R14 bitter taste receptor, revealing how it identifies and activates bitter tastants. The discovery has potential applications in drug development for metabolic diseases like obesity and diabetes.
Researchers found that adding rosiglitazone to medicines reduces bitterness for many people, but not all. The discovery may lead to more effective bitter blockers and improve medication adherence.
Belgian scientists developed AI models to predict beer ratings and aroma compounds, improving beer quality. The study analyzed hundreds of beers and used machine learning to connect chemical concentrations with appreciation scores.
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The study found that while cigarettes maintained market share, their popularity decreased, allowing for a more diverse marketplace at various price points. Modern oral nicotine products, such as nicotine pouches, emerged as the fastest-growing and most price-stable options.
Researchers at the University of Nottingham have discovered a way to create different colors of blue cheese by inducing sexual reproduction in the fungus Penicillium roqueforti. The team created various fungal strains that produce colors ranging from white to yellow-green, red-brown-pink, and light to dark blues.
Researchers at West Virginia University are using artificial intelligence to analyze habanero peppers and develop new methods for predicting genetic traits. The goal is to improve crop yields and prevent genetic diseases, with potential applications in human health.
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Researchers at ITMO University improved the nutritional value and taste of plant-based milks by using pre-freezing and ultrasound treatment methods. These methods boosted the extraction of beneficial microelements like iron, potassium, and zinc, as well as polyphenols, resulting in improved antioxidant activity.
Researchers have developed an AI algorithm that uses people's flavor impressions to make accurate predictions of individual wine preferences. The algorithm combines data from wine labels, user reviews, and sensory tastings to provide personalized recommendations.
A study published in Appetite found that the taste perception of ultra-processed foods is no better than that of less processed foods. Foods with a balanced carbohydrate-to-fat ratio and high dietary fibre content were more liked, while those with intense sweetness and saltiness were preferred.
Researchers at University of California - San Francisco find that sense of taste signals brain to slow down eating. Using advanced techniques, they recorded brain activity in awake mice and found PRLH neurons controlled by mouth signals when eating normally, not gut signals as previously thought.
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Researchers discovered a bitter taste receptor in sharks, similar to the one found in humans. This finding provides insights into the evolution of bitter taste perception, dating back around 500 million years.