Duke University researchers identify a new target for stopping drug resistance in cancer cells by targeting the cellular pump that expels chemotherapy drugs. The study found that certain immunosuppressive drugs can block this pump by removing a vital activator, FKBP12, allowing chemotherapy drugs to be effective.
Researchers are finding ways to repurpose old tires by using them in the construction of roads and retaining walls. Tire chips have been used successfully in three major new bridges in southern Maine and sections of three Maine roads, showing significantly less frost heave than conventionally built sections.
Researchers have developed a new technique to predict earthquake magnitude based on rock structure, providing more accurate assessments of seismic risk. By analyzing data from 37,000 earthquakes in southern California, the team created 3D images of subsurface rock formations that reveal varying maximum depths along and across faults.