Researchers at University of Rochester and NIH discover new HAT that plays critical role in transcription, providing strong evidence for chromatin-unfolding mechanism of gene activation. The finding has significant implications for understanding cell survival, proper development, and evolution.
Researchers discovered a genetic mutation in the TIE-2 gene responsible for venous malformations, the most common type of birthmark. The mutation disrupts the normal molecular dialog between endothelial cells and their environment, leading to abnormal blood vessel formation.
Copolymer-1 has been approved by the FDA for treatment of relapsing-remitting multiple sclerosis, demonstrating its ability to reduce attack frequency and minimize negative side effects. The drug works by blocking the immune system's attack on myelin coatings and triggering immune suppressor cells.