Visualization Of Fragile X Protein Helps Explain Its Function And Possible Relation To Mental Retardation
The study provides evidence that FMRP is transported into the cell's nucleus where it forms a complex with particular mRNAs and then is transported out of the nucleus to join ribosomes in the neuronal cytoplasm. The researchers discovered that free ribosomes, found in dendrites and dendritic spines, associate with FMRP.