Researchers at Johns Hopkins have modified established drugs to stimulate nerve growth without suppressing the immune system, a critical step toward treating neurodegenerative diseases. The new compounds were able to regenerate lost branches of nerve cells and cause recovery of functions in lab animals.
A study has found that human chorionic gonadotropin (hCG) reduces HIV viral protein production and protects against skin lesions in transgenic mice. The hormone may also explain the low rate of mother-to-infant HIV transmission, and has potential for treating wasting syndrome in children and adults.
Coral reefs face an alarming decline due to unknown causes, including coral bleaching and diseases. The loss of these ecosystems could have severe consequences for thousands of species and the global economy.
Researchers found that a lower free-to-total PSA ratio may indicate aggressive prostate cancer. The study suggests this ratio can help doctors distinguish between serious and non-serious cases, leading to better treatment decisions.
Women with polycystic ovary syndrome (PCOS) may experience menstrual irregularities, infertility, and increased body hair due to hormonal imbalances. Research suggests that PCOS may be inherited, affecting both males and females in the family.
Researchers will test the effects of microgravity on plant species known as sweet wormwood and rosy periwinkle, which naturally produce pharmaceutically important compounds. The goal is to develop new drugs or lower production costs.
A transgenic mouse model of Huntington's disease has been developed, exhibiting symptoms resembling chorea and epileptic seizures. The R-6 strain is the first known mouse model to display these characteristics, allowing researchers to study the disease's progression.
Researchers have developed a new treatment using human mesenchymal stem cells that can regenerate tissue and reduce healing time after tendon surgery. The treatment has shown promising results in animal models, with improved tendon repair strength and quality of tissue within four weeks.