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Science News for June 22, 1999


Rats operate robotic arm via brain activity

Researchers developed a method to record brain signals onto electrode arrays in rats, enabling them to control a robotic arm without muscle movement. This achievement demonstrates the likelihood of implanting electrodes into human brains to control prosthetic devices.

SourceDuke University·JournalNature Neuroscience·DateJun 22, 1999

Protein essential for making steroids turns out to be a "molten globule"

The StAR protein plays a key role in the steroid-making system by partially unfolding to form a 'molten globule' conformation that enables it to work inside cells. This flexible state lowers energy required for channel opening in mitochondrial membrane, acting as an on/off switch for cholesterol transport.

SourceUniversity of California - San Francisco·JournalProceedings of the National Academy of Sciences·DateJun 22, 1999

Gladstone/UCSF team discovers interaction of two brain proteins may be key factor in development of Alzheimer's disease

A team of scientists has found a critical interaction between two brain proteins that could help explain the death of nerve cells in Alzheimer's disease. The discovery reveals that normal APP provides a protective function against cell death, while mutant forms do not.

SourceUniversity of California - San Francisco·JournalProceedings of the National Academy of Sciences·DateJun 22, 1999