Researchers at UCSF have discovered how Mycobacterium tuberculosis outsmarts the immune system to cause disease. The microbe disrupts a protein called STAT1, blocking macrophages' ability to respond to interferon gamma, allowing it to survive and infect other cells.
The Pacific Ovarian Cancer Research Consortium aims to discover genes, develop a cancer vaccine, and improve treatment outcomes for ovarian cancer. The five-year study will involve researchers from several institutions and involve at least 3,500 women in its various studies.
Researchers have uncovered six complete bone flutes at a 9,000-year-old Neolithic site in China, which may be the earliest complete, playable, and tightly-dated musical instruments. The flutes, made from red-crowned crane wing bones, have been analyzed and played, revealing a tone scale similar to the Western eight-note scale.
A new Mayo Clinic study confirms that bed partners experience significant improvements in sleep quality when their husbands are treated for obstructive sleep apnea. The average percentage of time spent sleeping increases from 74% to 87%, adding over an extra hour of sleep per night.
The Western Regional Meeting of the American Chemical Society will feature over 300 papers on topics such as environmental science and organic/biochemistry. Dr. Jerome Karle, a Nobel Prize winner, will address the conference.
A University of Iowa research team discovered that DNA methylation can contribute to oral cancer by silencing tumor suppressor genes. The study found that aberrant cytosine methylation patterns were present in oral cancer cells but not in normal human cells, suggesting a potential mechanism for cancer progression.
A new study by University of Washington researchers reveals that dyslexic children use significantly more brain area and energy while performing simple language tasks. The findings provide new evidence that dyslexia is a brain-based disorder and shed light on its developmental mechanisms.
A new device called a magnetorheological damper has been tested on a model building set atop an earthquake-simulating shake table, showing promise in minimizing damage in earthquakes. The device reduces the peak acceleration by 50 percent, and is designed to be inexpensive, straightforward, and powered by a battery.
A University of Chicago study found that neighborhoods with more racially integrated populations have higher rates of bystander CPR during cardiac arrests. In contrast, predominantly white and black neighborhoods had lower CPR rates.
Researchers found that a common mutation in the CYP17 gene is associated with higher testosterone levels and larger, stronger bones in men. The study measured hormone levels, stature, and bone mass in 333 Caucasian men aged 51-84 years.
The Networked Digital Library of Theses and Dissertations (NDLTD) is expanding internationally, with UNESCO joining and collaborations with the NSF, DFG, and ISTEC. These partnerships aim to overcome language and policy challenges, enabling easier sharing of electronic theses and dissertations across countries.
Researchers suggest that testosterone plays a key role in redistributing immune cells to the skin during stress, rather than suppressing the immune system. This redistribution hypothesis is supported by studies in rats and mice, which show improved wound healing rates with testosterone treatment.
A large-scale national study will investigate whether weight loss reduces cardiovascular disease and slows atherosclerosis progression in obese people with type 2 diabetes. The 7-year trial, funded by the National Institute of Diabetes and Digestive and Kidney Disorders, aims to enroll 6,000 participants.
Researchers found slight memory impairment in children on intensive diabetes therapy, with a three-fold higher rate of severe hypoglycemic incidents compared to conventional therapy. The study suggests potential long-term cognitive consequences related to repeated hypoglycemic episodes.
John Moffat, a University of Toronto professor, proposes that the speed of light was not always constant but rather increased over time. This theory could help explain recent discoveries about the accelerating expansion of the universe and provide an answer to some cosmology problems.
Researchers have identified two genes contributing to asthma development: interleukin IL4 and IL13. Decreasing their activity may help reduce asthma attacks, with potential applications to other complex genetic conditions.
Researchers found that loss of the NEP enzyme fuels inflammation in mice with colitis, leading to increased substance P levels and bowel inflammation. Administering the NEP enzyme or blocking substance P can dramatically reduce inflammation, suggesting potential treatments for humans.
Researchers found that calcium absorption decreased with age, especially after the age of 80, leading to increased risk of osteoporosis in older men. Higher levels of fractional calcium absorption were associated with slower rates of hip bone loss.
Diane Coley McGann, a Santa Ana High School teacher, receives the Western Regional High School Chemistry Teaching Award for her innovative approach to motivating students. She has also created a series of workshops to assist teachers in promoting chemistry education.