A daily dose of fish oil significantly improves kidney function and reduces the risk of advanced kidney failure in people with IgA nephropathy. Researchers followed 106 study participants for over six years, finding sustained benefits from fish oil supplementation.
A recent study by the Mayo Clinic found that 10 out of 16 men experienced a greater than 50% reduction in hot flashes while taking venlafaxine. The incidence of severe and very severe hot flashes was also significantly reduced.
Scientists discover that removing two proteins controlling cell proliferation can lead to deadly consequences, including leukemia and immune system dysfunction. The study reveals critical regulatory roles of SOCS1 in T cells and its absence makes cells sensitive to cytokines.
A major study found that children whose mothers are chronically depressed perform significantly worse on tests of verbal comprehension, language skills, and school readiness compared to those with no maternal depression. Mothers who were sometimes depressed fell somewhere in between.
Children of depressed mothers performed poorly on measures of school readiness, verbal comprehension, and expressive language skills. However, maternal sensitivity played a crucial role in the well-being of children, even when mothers were depressed.
Scientists have developed a method to deliver large proteins into cells using a molecular passport. The technology allows for lower doses and fewer side effects, making it a promising avenue for therapeutic approaches. This breakthrough could enable the creation of drugs that act only in disease-related cells.
Researchers successfully delivered fully functional proteins inside cells using a piece of the AIDS virus, overcoming the bioavailability wall that restricts large molecules. This technique has the potential to treat diseases such as cancer and genetic disorders by inserting working versions of damaged proteins into affected cells.
A study by Mayo Clinic pediatrician Philip R. Fischer found that pseudoephedrine hydrochloride was not effective in decreasing ear pain in children during air travel. Offering food or drink can help relieve pressure and clear earache, with swallowing sometimes helping to open eustachian tubes.
A new HIV drug intervention using nevirapine is significantly cheaper and more effective than three similar treatments, preventing 603 infections at a cost of $80,000 per year. The universal nevirapine program is the most cost-effective option, with a treatment cost of $138 to prevent one case of infant HIV.
Gene-repair pioneer Eric Kmiec has established the University of Delaware's Laboratory of Gene Therapy, focusing on sickle-cell anemia, Huntington's Disease and food-crop advances. His technique repairs genetic mutations by stitching mutated sequences back together in their proper order.
Researchers at Thomas Jefferson University have isolated hematopoietic stem cells using a specific marker, enabling laboratory production of all types of blood cells. This breakthrough has the potential to alleviate blood shortages for transfusions and develop innovative approaches to bone marrow transplants and gene therapy.