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Science News for January 2, 2000


UI study looks at cellular mechanism involved in hypertension

A University of Iowa researcher has found that ion channels in the kidney play a critical role in regulating blood pressure and that a hormone called vasopressin stimulates these channels to increase sodium absorption, leading to hypertension. The study provides new insights into Liddle's syndrome, a rare genetic form of hypertension.

SourceUniversity of Iowa·JournalJournal of Clinical Investigation·DateJan 2, 2000
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UM researchers discover 'key' to blood-brain barrier

Researchers at University of Maryland School of Medicine identified zonulin and zot proteins in human brain that regulate the blood-brain barrier. This discovery could lead to new treatments for brain disorders such as Multiple Sclerosis, Alzheimer's disease, and HIV infection.

SourceUniversity of Maryland Medical Center·JournalJournal of Neurochemistry·DateJan 2, 2000
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Common enzyme deficiency may jeopardize pregnancies

A study found that glucose-6-phosphate dehydrogenase (G6PD) is critical to embryonic development, increasing the risk of prenatal and postnatal death. The deficiency also increases the incidence of birth defects in fetuses exposed to oxidative stress.

SourceUniversity of Toronto·DateJan 2, 2000