The study identifies six transcripts whose up- or down-regulation in rheumatoid arthritis (RA) parallels the changes seen in anergic cells. Calmodulin suppression in RA is consistent and dramatic, suggesting a link between anergic cells and disease-associated T cells.
Researchers found that HBV polymerase mutations can restore viral replication rate while maintaining drug resistance, affecting treatment efficacy. Entecavir proved effective against even the most vigorous drug-resistant mutants, offering a promising alternative to lamivudine.
Researchers followed women with advanced disease to see which HIV variants remain after HAART. They found that R5 viruses can re-emerge as the predominant population following treatment.