Dr. Teitelbaum's research reveals that blocking integrin receptors on osteoclasts can prevent bone loss in osteoporosis and rheumatoid arthritis, offering new drug targets. Additionally, his work has shed light on the effects of protease inhibitors on osteoclasts in HIV/AIDS patients.
Researchers found that omega-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) inhibited the growth of liver cancer cells, whereas omega-6 fatty acid arachidonic acid (AA) had no effect. The compounds induced apoptosis and decreased beta-catenin levels, which are involved in tumor progression.
The HealthGrades study reveals a significant increase in hospital incidents, with Medicare patients experiencing one-in-four chance of dying during hospitalization. Top-performing hospitals and states like Minnesota show progress in patient safety, with potential cost savings of $2.45 billion.
Research reveals that fish larvae can't maintain a horizontal body position while coasting, leading to increased drag and poor swimming abilities. This conclusion refutes previous theories on poor hatchling swimming, providing new insights into pectoral fin development and swimbladder formation.
The APS lecturer's videos provided a real-time look at immune cell interactions in a mouse lymph node, highlighting how dendritic cells teach T cells to respond to infections. The research focuses on leukocyte recruitment and trafficking, particularly in the lymph nodes.
Researchers have discovered the structure of Anopheles gambiae's 3-hydroxykynurenine transaminase, a key enzyme in its oxidative defense mechanism. This finding could lead to the development of novel antimalarial agents by inhibiting this enzyme and disrupting the malaria parasite's lifecycle.
The Society for Experimental Biology is developing a new e-journal to showcase top UK undergraduate research. Interested stakeholders are keen to use the system, which aims to address concerns around copyright and incorporate online review procedures.
The Mayo Clinic research identifies a signaling mechanism by which natural killer cells initiate a toxic response against cancers and viruses. The discovery provides crucial information for designing therapies to stop, reverse or protect against cancer.
Research using government data found that children consuming 100% juice had lower z-scores for body mass index than non-juice consumers. Total fruit intake was three times higher among juice consumers, supporting the nutritional benefits of whole fruits and juices.
A study published at the AACR annual meeting found that a history of allergies and asthma significantly reduces the risk of developing brain tumors. Individuals with allergies or asthma had a lower risk of glioblastoma, mid-grade anaplastic astrocytoma, and low-grade gliomas compared to those without these conditions.
A study of 216 individuals found that those living on the coast reported more health issues, with a mean symptom score of 14.1 compared to inland residents. The authors conclude that long-term effects of crude oil spills on local populations warrant further investigation.
Researchers found a significant increase in cancer risk among first-degree relatives of lung cancer patients, particularly young onset cancers. The study's findings suggest that genetic factors play a crucial role in the development of lung cancer and other types of cancer.
Researchers have identified a multi-marker panel of 20 proteins that correctly recognize over 98% of serum samples from women with ovarian cancer, offering higher diagnostic power than any other published assay. The study uses novel technology to analyze multiple proteins in a single drop of blood or serum and aims to develop this scre...
Native insects provide valuable services worth $50 billion in recreation industry, $4.5 billion in pest control, $3 billion in crop pollination, and conserving grazing lands valued at $380 million annually. Insects are crucial for human survival, and their ecological functions need to be conserved or enhanced through research investment.
A new scientific review highlights the effectiveness of vegetarian diets in promoting weight loss, with body weights averaging 3-20% lower than meat-eaters. A low-fat vegan diet leads to a weekly weight loss of about 1 pound without additional exercise or calorie restrictions.
Researchers found that waves in cancer cells selectively round up activated growth-promoting proteins, which can help terminate signals and prevent cancerous traits. This discovery provides new insights into the role of waves in cancer cell metastasis.
Researchers found that individuals with depression who exhibit increased activity in certain brain regions are more likely to respond to CBT. The study used fMRI to identify these regions, which included the subgenual cingulate cortex and amygdala.
A study by Losey and Vaughan estimates the economic value of ecological services provided by insects at $57 billion annually in the United States. The services include natural control of crop pests, pollination, and wildlife nutrition, valued at $4.5 billion, $3 billion, and $50 billion respectively.
A Mayo Clinic study found that a specific gene profile of HOXB13 and IL17BR is an independent marker of early breast cancer relapse or death in lymph node-negative breast cancer. This discovery has significant clinical implications, suggesting the potential for improved treatment outcomes for high-risk patients.