Dr. E. Richard Stanley has been recognized with the 2006 E. Donnall Thomas Prize for his groundbreaking research on CSF-1, which plays a crucial role in regulating cell proliferation, differentiation, and function in various diseases. His studies have also shed light on the roles of CSF-1 and its receptor in development and cancer.
Researchers have found that human embryonic stem cells exhibit a distinct pattern of DNA methylation, differing from adult cells and cancer cells. This discovery may hinder the success of therapeutic cloning by requiring epigenetic reprogramming of adult cells.
Researchers used real-time imaging to track malaria infections in live mice, discovering that the parasite uses dead liver cells to cloak and transport itself back into the bloodstream. The study provides insights into the parasite's complex life cycle and potential ways to treat malaria.
Dental patients taking oral bisphosphonates should be aware of potential risks during procedures involving the jaw bone. The American Dental Association recommends a comprehensive oral evaluation and education on maintaining oral hygiene to prevent oral diseases.
Researchers found that high blood pressure causes hearts to have lower fat metabolism, relying more on carbohydrates for energy. This shift can lead to impaired heart function and increased risk of heart failure.
The study reveals the three-dimensional structure of the smallpox virus topoisomerase-DNA complex, providing crucial insights into how the viral enzyme recognizes and activates specific DNA sequences. This knowledge will facilitate the design of targeted agents to combat poxvirus infections and prevent smallpox replication.
A $14.6 million NIH grant will fund an international, multidisciplinary effort to leverage recent genetic discoveries into possible treatments for AMD. The investigation aims to explore the role of complement factor H and factor B genes in the immune system and develop diagnostic tools and treatments.
Researchers at University at Buffalo found that methamphetamine increases expression of DC-SIGN receptor, allowing more virus to invade the immune system and promote HIV infection. The study suggests that dopamine receptor blockers could be beneficial in reducing HIV infection in high-risk populations.
A recent study found that extreme heat increases mortality risk among the elderly, diabetics, and African Americans. The research analyzed 7.8 million deaths across US cities from 1989 to 2000, revealing a significant association between extreme temperatures and cardiovascular-related deaths in African Americans.
The median age of San Francisco's homeless population has increased significantly over 14 years, shifting from 37 to 46. Chronic diseases related to homelessness are a major contributor to this trend. Researchers at UCSF have found worsening health status and chronic conditions among aging homeless adults.
Researchers found that longer train trips lead to increased physiological and psychological stress, as well as impaired task completion. Commuter stress affects human health and well-being, with over 100 million Americans experiencing daily stress due to their commute.
Researchers at UCLA compared neural stem cells grown in the lab to those derived from donated fetal tissue and found the former expressed lower levels of a metabolic gene called CPT 1A. This abnormality may impact the effectiveness of these stem cells in treating diseases such as Parkinson's and Alzheimer's.
Current brain cooling devices may not be effective in reducing injury from stroke and head trauma as they can't penetrate deeply into the brain. The new findings suggest that most patients won't benefit from these techniques, and a different approach is needed for certain patients.
The University of Alaska Fairbanks' Geophysical Institute has acquired an Insitu A-20 unmanned aircraft system, which will facilitate various research projects across Alaska. The aircraft's capabilities include wildfire mapping, pipeline security, and large mammal tracking, offering unique opportunities for students and faculty.
Researchers urge governments to implement stricter controls on the live reef fish trade, a growing threat to coral reefs. The trade has devastating effects on the ecosystem, including the depletion of coral reef stocks and the spread of destructive harvesting methods.
A large-scale study found that adding a broad-spectrum psychotropic agent, Risperidone, to standard antidepressant therapy can effectively treat resistant major depressive disorder. Patients who were less severely ill only needed a brief period of Risperidone treatment to experience lasting benefits.
Researchers at Washington University School of Medicine found that nearly half of children with attention-deficit/hyperactivity disorder (ADHD) are not receiving treatment. The study, which analyzed data from over 1,600 twins, suggests that many cases of ADHD may be underdiagnosed or undertreated.
Researchers developed transgenic goats with human lysozyme genes, which produce antibacterial milk that reduces coliform bacteria in pigs. In contrast, kid goats showed no significant difference. The findings demonstrate potential benefits of biotechnology-enhanced dairy animals for human health.