A new study found that postmenopausal women who stop taking the osteoporosis drug alendronate after 5 years do not increase their risk of nonvertebral fractures, suggesting a lasting effect. The research also shows that BMD and bone marker levels remain at or above pretreatment levels 10 years after discontinuation.
The study found a significant decline in stroke incidence over the past 50 years, with lifetime risk decreasing from 19.5% to 14.5%. However, age-adjusted stroke severity remained unchanged, and mortality rates only decreased in men, highlighting the need for greater primary prevention efforts.
A study found that people enjoy video games because they find them intrinsically satisfying, with benefits including achievement, freedom, and connection to others. The research suggests that some video games can motivate further play and even enhance psychological wellness.
A large-scale study found that prolonged use of proton pump inhibitors (PPIs) increases the risk of hip fractures by 44%. Long-term users of high-dose PPIs face a significantly higher risk, highlighting the need for further research into the underlying mechanism.
Researchers have identified genes and signaling pathways that enable zebrafish to regrow their tail fins. The study suggests that humans may also have untapped regenerative powers hidden in their genes, potentially leading to new treatments for human injuries.
Researchers have developed a new 3D scaffold made of protein nanofibers that can support the growth and differentiation of stem cells. The scaffold provides a more accurate representation of the natural context of cells in tissues and organs, and has the potential to replace traditional Petri dishes for growing cells.
Researchers have identified a new 'glucose sensor' that plays a crucial role in glucose metabolism and fat synthesis, potentially leading to new treatments for obesity and diabetes. The discovery highlights the significance of the Liver X Receptors (LXRs) in regulating gene expression linked to cholesterol and fat metabolism.
A new tree-ring study links episodic fire outbreaks in the past five centuries with periods of warming sea surface temperatures in the North Atlantic. The study suggests that warmer waters in the North Atlantic correspond with episodes of drought and subsequent fires in the West.
A study of Finnish working-aged adults found that pet ownership is associated with a higher risk of illness and lower physical activity levels. Dog owners did exhibit increased physical activity compared to non-dog owners, however this was not enough to offset the negative health effects of pet ownership.