The center will investigate disparities in modifiable risk factors for breast cancer, particularly among African-American women, and examine demographic, lifestyle, medical, and genetic profiles for obesity. The research aims to develop predictive models and biomarkers to improve early detection and treatment of breast cancer.
The study found that endovascular aneurysm repair (EVAR) significantly reduced mortality rates and recovery time for patients undergoing AAA repair, even among older and less-fit patients. The procedure's success has influenced overall AAA repair outcomes.
Researchers have created genetically modified mosquitoes resistant to the Type 2 dengue fever virus, which infects 50 million people annually. The mosquitoes showed high levels of resistance and were able to reproduce, making them a promising tool for controlling mosquito-borne diseases.
Researchers at the Salk Institute identified V1 neurons as crucial for controlling rhythmic movements in the spinal cord, which enables walking. Disabling these neurons slows down the movement, highlighting their importance in locomotion.
Research from the University of Warwick reveals that increased levels of sE-selectin are strongly associated with measures of obesity and waist fat. This inflammation can lead to various health issues like thrombosis, heart disease, strokes, and diabetes.
A study of over 4500 women reveals that nearly 10% of repeat cesarean deliveries have no documented reason, emphasizing the importance of accurate physician-recorded indications. Future research should focus on clinicians' and women's decision-making processes about childbirth after a prior cesarean delivery.
A new study found that early antiretroviral therapy can significantly improve CD4 cell count outcomes in HIV-infected infants. Children who started treatment between 5 months and 5 years of age were 60% less likely to experience a decline in their CD4 cell count z-score compared to those who started treatment before 5 months.
A study in the Journal of Nuclear Medicine Technology found that physical activity, even minor exercises like turning a page or shoveling snow, can impact PET scan results and lead to false positives. To minimize this effect, patients should avoid excessive muscle activity 48 hours before scanning and inform their technologist.
Researchers used PET scans to monitor artificially induced lung inflammation in healthy volunteers, allowing for less invasive testing of potential anti-inflammatory drugs. The new imaging process may help diagnose inflammatory lung diseases and improve clinical trials.
Researchers developed a genome-wide map of miRNA-mRNA interactions using the PicTar algorithm, predicting that one-third of C. elegans miRNAs target related genes. The study also found that 3' UTRs contain a largely unexplored universe for gene regulation.
The study found a net loss of ice from the combined polar ice sheets between 1992 and 2002, resulting in an increase in sea level. The survey also documented extensive thinning of the West Antarctic ice shelves and an increase in snowfall in Greenland.
Researchers at Ohio University found that salamanders and the ancient lizard-like animal tuatara can both walk and run on land, using energy-saving mechanisms similar to those in fast-running animals. This discovery suggests that these early vertebrates may have had a key role in shaping the evolution of locomotion in later species.
A new study provides evidence that consuming three servings of low-fat dairy foods per day can aid in weight loss and promote overall health. The research, consistent with the 2005 Dietary Guidelines for Americans, highlights the benefits of dairy consumption on body weight.
Researchers analyze gamma-ray burst GRB 050904 to understand the conditions of the early universe. The burst, detected in 2005, provides a probe to study the universe beyond the reach of large telescopes.
The study found that combination vaccine groups had significantly higher coverage rates for various vaccines, including DTaP, polio, and hepatitis B. Additionally, children in the combination cohort received their vaccinations on time more frequently than those in the component cohort.
The MIT team uses particle-spring systems to create three-dimensional designs that can find a structure's most efficient form in minutes. Historically, finding new structural forms required physical means, but this method offers a more efficient and sustainable approach.
Researchers at MIT have discovered a compound called B2 that promotes the formation of large protein inclusions, which may help stop Huntington's disease progression. The compound also shows promise for treating Parkinson's disease, another neurodegenerative disorder caused by misfolded proteins.
The stent-graft approach has been shown to result in less neck nerve injury and faster recovery compared to open neck surgery. This minimally invasive treatment can be performed under local anesthesia and allows patients to resume normal activities within two days.
Researchers used fMRI to examine how brains process object size under illusions, finding the primary visual cortex activated more area for a distant object. This challenges the long-held view that the image is just a precise reflection of the retina.
A team of Cornell University researchers used golden hamsters to study individual recognition, finding that different brain areas react differently depending on emotions attached to memories. The study's findings may have implications for understanding and treating social anxiety disorders, Asperger syndrome, and autism.
Researchers have identified a new target for obesity treatment by discovering a small molecule that activates the G protein-coupled receptor GPR119, leading to reduced food intake and weight gain in rats. The compound, PSN632408, also shows promise in improving lipid profiles and insulin sensitivity.
A new study at Brandeis University found that middle-aged and older adults who believe they can control their memory performance do so better. The study used mnemonic strategies to enhance memory performance in adults aged 21-83.
John Wieczorek receives Ebbe Nielsen Prize for his work on integrating biosystematics and biodiversity informatics research. He will use the prize to expand projects in North America and beyond.
A study by Johns Hopkins Bloomberg School of Public Health found that short-term exposure to fine particulate matter increased hospital admissions for cardiovascular and respiratory diseases. The study estimated associations between day-to-day changes in hospital admission rates and fine particulate matter levels in 204 US urban counties.
A Kansas State University marketing professor studied the relationship between product characteristics and consumer behavior in online shopping. He found that a superior website experience enhances customer satisfaction, especially for female consumers who value convenience and organization.
The VBI Microbial Database provides genome sequence and annotation data for two major plant pathogens, Phytophthora sojae and Phytophthora ramorum. The database offers powerful analytical tools and community annotation features to facilitate research on these pathogens.
Researchers found that serotonin levels in pacemaker cells are crucial for gasping and auto-resuscitation in babies. Disturbed serotonin levels can lead to a decrease in gasping, making it difficult for the baby to wake up and initiate movement.
A recent study found that sexual harassment cases governed by the 1991 Act are awarded statistically significant higher damages awards than preceding cases. The inclusion of state law tort and anti-discrimination claims drives up damages.
Older subjects showed a significant increase in exercise efficiency and reduced oxygen debt after aerobic exercise training. The study's findings suggest that a lack of fitness, rather than aging itself, contributes to the decline in exercise capacity.
Researchers found that cells adapt to low oxygen conditions by inhibiting mitochondrial function and increasing the conversion of glucose to lactate. This active process, mediated by hypoxia-inducible factor-1 (HIF-1), helps protect tumor cells from death and may be targeted by cancer therapies.
A study found that coffee consumption is associated with an increased risk of nonfatal heart attack among individuals with the slow CYP1A2*1F allele, which impairs caffeine metabolism. Those who drank more than 4 cups per day had a significantly higher risk compared to those who consumed less.
A study on Maori infertility aims to address the lack of quality information on the issue, which is affecting declining family sizes among Maori. The research will gather views from different Maori groups to inform improvements in reproductive healthcare.
A study found that mental stress can reduce heart blood flow in patients with coronary artery disease, even those without symptoms of ischemia during physical stress tests. Six out of 29 patients showed signs of ischemia on images produced after a mentally stressful role-playing scenario.
Patients identified seven ideal physician behaviors: confident, empathetic, humane, personal, forthright, respectful, and thorough. Training physicians on interpersonal skills may improve patient outcomes.
Researchers identified common properties among genes implicated in cancer development through a bioinformatic study. The study suggests that random breakage is a key mechanism in tumor formation, with a database of genome regions revealing characteristics of these breaks.
Fine particulate matter exposure (PM2.5) was associated with short-term increases in hospital admission rates for all health outcomes except injuries. Cardiovascular risks were highest in Eastern US counties, with a 1.28% increase in heart failure risk per 10-µg/m3 PM2.5.
A Cornell University study reveals that male loons modify their yodels when switching territories, adopting a new call to signal dominance. This unique behavior has significant implications for conservation efforts and may inform the development of non-invasive bird identification methods.
A 'shuttling' protein, ATF2, previously confined to the nucleus of healthy cells, has been found to shuttle between the nucleus and cytoplasm in cancer cells. This shuttling is controlled by the presence of another protein, c-Jun, and may play a key role in cancer's resistance to treatment.
A genetic switch discovered by Hopkins researchers deliberately shuts off a cell's mitochondrial combustion engine under low oxygen conditions. This switch limits the production of toxic oxygen molecules and prevents cellular damage.
Researchers suggest that increasing efficiency in medical practice and directing resources to effective care can reduce costs and improve patient outcomes. Studies have shown that patients with severe chronic illnesses receive excessive physician care, which may do more harm than good.
A study of 170 patients with chronic severe aortic regurgitation found that those who underwent early surgery lived longer and had better health outcomes compared to those who waited. The results support current guidelines for treatment, which recommend surgery for asymptomatic and moderately symptomatic patients.
University of Wisconsin-Madison researchers have created a liquid crystal-based cell culture system to control the uncontrolled differentiation of human embryonic stem cells. The system uses mechanical strain to guide stem cells along well-defined lineages, enabling real-time monitoring and reducing the mixture of cells of little medic...
Los Alamos scientists uncover new relationship between magnetism and unconventional superconductivity in complex materials. They demonstrate that magnetism can be made to reappear in the presence of an applied magnetic field, expanding our understanding of high-temperature superconductors.
Researchers developed a new way to study proteins in live cells, identifying interactions between Src and CrkL, and direct evidence of its role in MAP kinase pathways. This approach may lead to the development of new cancer treatments, such as targeting tyrosine kinases like Gleevec.
The study reveals that ion channels collaborate through a third protein called ankyrin-G to control electrical signals in the brain. This mechanism is present in all vertebrates but lacking in invertebrates, suggesting its importance for higher brain abilities.
Women's heart health is underestimated due to differing risk factors compared to men. The European Society of Cardiology recommends considering age as a significant factor in diagnosis and treatment planning for women.
A study found that a single mass antibiotic treatment does not prevent the return of eye infections in communities with high disease prevalence. Infection rates rose again after 2 years, highlighting the need for repeated treatments or other measures to eliminate infection.
Researchers at Johns Hopkins Medicine discovered that injecting ciliary neurotrophic factor (CNTF) into obese mice with leptin deficiency or resistance reduced their heart muscle walls by up to a third and the size of the left ventricle by 41%. This breakthrough suggests a novel brain-signaling pathway for obesity-related heart failure.
The Mars Express and NASA's Mars Reconnaissance Orbiter missions are providing valuable insights into Mars' upper interior. The combination of radars on the two missions will directly map the structure of the upper portions of the interior, revealing information about water, ice caps, and crust deformation.
A study by Washington University researchers reveals that heat-loving microbes create energy through various reactions, including the use of sulfur and hydrogen. The findings hold clues to the origin of life on Earth, suggesting a high-temperature environment as the likely last common ancestor.
A recent study indicates a significant increase in antibiotic-resistant community-acquired Staphylococcus aureus (MRSA) infections, affecting urban populations in the Atlanta area. The study reveals that 72% of community-onset skin and soft tissue infections are now due to MRSA USA300 strain.
A research team led by Professor Eberhard Bodenschatz has experimentally tested two theories on how particles separate in strong turbulence. The results, which agree with George Batchelor's predictions but not the Richardson-Obukhov law, suggest that particles move more slowly away from each other than previously assumed.
Researchers isolated genes from the starlet sea anemone to understand body-plan patterning. They found that two types of proteins encoded by these genes are expressed differently in anemones compared to bilateral animals like flies and frogs, suggesting an ancient function for this signaling system.
The NCAR team predicts that Cycle 24 will produce larger-than-usual sunspots, affecting satellite orbits and power systems. Scientists developed a model tracking subsurface movements of sunspot remnants for more than 98% accurate forecasts.
Scientists at NIST have developed an experimental atomic clock using ytterbium 'pancakes' that could be more stable and accurate than current time standards. The new design holds thousands of atoms in a lattice made of intersecting laser beams, which is also applicable to other atoms with even-numbered atomic masses.
Researchers have developed a method to estimate oxygen levels in grain boundaries of superconductors, which can enhance their critical current density. This technique, called pressure-induced oxygen relaxation, could make it easier to manufacture reliable ceramic superconductors.
Researchers found that free-living hummingbirds in Canadian Rocky Mountains have impressive timing abilities, remembering interval between visits to individual flowers. They can maintain 'independent stopwatches' for up to eight different flowers, allowing them to plan efficient nectar harvesting
Researchers discovered that bats employ sophisticated techniques to locate prey in cluttered environments, including adjusting the timing and frequency of their ultrasonic pulses. By analyzing high-speed camera footage and audio recordings, the team found that bats 'strobe' the air with sound to distinguish insects from background noise.
A team of researchers from Johns Hopkins University and Los Alamos National Laboratory found that large fluid vortices raid their smaller neighbors in an energy grab, sustaining a steady-state inverse energy cascade. This phenomenon forms a food-chain of vortices, with larger ones preying on smaller ones.
A recent study suggests that depressive symptoms in adolescent girls may be a predictor of subsequent partner violence. Among the 1,659 girls involved in an opposite-sex relationship, those with high depressive symptoms were found to be 86% more likely to experience moderate to severe partner violence.