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Science News for November 16, 2006


World Health Organization in the era of Margaret Chan

Margaret Chan takes over as WHO Director-General on January 4, 2007, with a daunting task of prioritizing programs amidst widespread failures in malaria, tuberculosis, HIV-AIDS, child mortality, and maternal health. The Lancet Editorial highlights her need to create an operational team that commands confidence from member states.

SourceThe Lancet_DELETED·JournalThe Lancet·DateNov 16, 2006

New HIV statistics indicate increasing toll of AIDS on African American community

The African-American community is facing a disproportionate impact of HIV/AIDS, with over half of all new diagnoses among this group. The National Minority AIDS Council recommends five policy solutions to address this disparity, including eliminating stigma against black MSM and reducing the role of injection drug use in sustaining the...

Hormone replacement therapy may improve trip down memory lane

A new study from the University of Michigan Health System suggests that hormone therapy may help retain certain memory functions in postmenopausal women. The research found increased brain activity in the prefrontal cortex of participants taking combined estrogen-progestin hormone therapy, compared to those on placebo.

SourceMichigan Medicine - University of Michigan·JournalThe Journal of Clinical Endocrinology & Metabolism·DateNov 16, 2006

ADAPT safety results now published

The study found a potential increased risk of cardiovascular events among elderly individuals taking naproxen, while celecoxib showed no significant risk. The results contribute to the larger body of evidence on the safety of these non-steroidal anti-inflammatory drugs.

SourcePLOS·JournalPLOS Clinical Trials·DateNov 16, 2006

Nanotech tools yield DNA transcription breakthrough

Researchers have resolved key questions about DNA transcription using nanotech tools, revealing a molecular machine that remains stationary and 'reels in' adjacent DNA segments during initial synthesis. This breakthrough advances understanding of the structure and function of transcription, setting the stage for new opportunities in co...

SourceRutgers University·JournalScience·DateNov 16, 2006

Repair not destruction: A new approach to treating retinopathy

Researchers propose a novel treatment strategy for retinopathy by repairing abnormal blood vessels instead of destroying them. The study shows that transplanted bone marrow-derived cells can convert leaky blood vessels into normal ones, suggesting a potential therapy for human diseases like ROP.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateNov 16, 2006

Edible food wrap kills deadly E. coli bacteria

A new edible coating composed of apple puree and oregano oil has shown promise in killing deadly E. coli bacteria while providing flavor enhancement to food. The coating's effectiveness was demonstrated through laboratory studies, which found it to be more concentrated and longer-lasting than conventional produce washes.

SourceAmerican Chemical Society·JournalJournal of Agricultural and Food Chemistry·DateNov 16, 2006

Study shows survival benefit for anastrozole

A recent study published in The Lancet Oncology found that switching to anastrozole after 2-3 years of tamoxifen treatment significantly improves overall survival and reduces the risk of recurrence for postmenopausal women with hormone-sensitive early-stage breast cancer. The study analyzed data from three trials and used meta-analysis...

SourceThe Lancet_DELETED·JournalThe Lancet Oncology·DateNov 16, 2006

JCI table of contents: November 16, 2006

Researchers suggest repairing abnormal blood vessels in retinopathy using adult bone marrow–derived myeloid progenitor cells. Dendritic cells form part of granuloma walls containing Listeria monocytogenes, maintaining integrity through immunosuppressive protein IDO.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateNov 16, 2006

Robot, heal thyself

Dr. Joshua Bongard's research enables robots to detect damage and teach themselves to continue walking despite missing limbs. This innovation is crucial for NASA's planetary missions where robots need to be able to fix themselves without human assistance.

SourceUniversity of Vermont·JournalScience·DateNov 16, 2006

New study weighs benefits of exercise, diets

A new study found that exercising regularly can lead to more effective weight loss than following a calorie-restricted diet, as exercise helps preserve muscle mass and improve aerobic capacity. Those who exercised lost between 9-10% of their body weight, while dieters lost 9-10%, but also experienced reduced muscle mass.

SourceSaint Louis University·JournalJournal of Applied Physiology·DateNov 16, 2006