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Science News for February 5, 2007


Evolutionary influences on proteins

Researchers found that splice-enhancer domains, which code for specific amino acids, influence protein evolution and are subject to selective pressure. Smaller exons near intron-exon boundaries also evolve more slowly.

SourcePLOS·JournalPLOS Biology·DateFeb 5, 2007

Contraceptives and the poor; plus new findings on cryptococcosis

Researchers found that the poorest people in developing countries are least likely to use contraception, with significant regional variations. The authors emphasize the need for governments and international health organizations to focus on providing contraceptive services to those with very low incomes.

SourcePLOS·JournalPLOS Medicine·DateFeb 5, 2007

Bioengineering efficient antibiotic biosynthesis in E. coli

Researchers used bioassay-guided evolution to identify more efficient antibiotic-producing mutants in Escherichia coli, reconstituting the biosynthetic pathways of sugars to yield a new antibiotic. This approach opens doors for harnessing genetics to investigate polyketide synthases and biosynthetic engineering.

SourcePLOS·JournalPLOS Biology·DateFeb 5, 2007

FISH-ing for links between cancer and aging

Scientists have linked telomere loss to both cancer and aging by visualizing chromosomes of cells from patients with Werner Syndrome. Rebuilding structures called telomeres significantly blocks genetic damage seen in cells of patients with Werner Syndrome.

SourceSalk Institute·JournalProceedings of the National Academy of Sciences·DateFeb 5, 2007

European medical research still ignoring women

A study of European research ethics committees found that while some had informal rules for gender diversity, few had formal requirements to ensure equal representation of both sexes. Despite EU policy on gender equality in health research, limited attention was paid to these issues.

SourceBMJ Specialty Journals·JournalJournal of Medical Ethics·DateFeb 5, 2007

Low birth weight and childhood abuse linked to psychological problems later in life

Children born with low birth weight are more likely to develop depression and social dysfunction if they experience child abuse, according to a recent study. The study found that those who suffered both low birth weight and child abuse had significantly poorer outcomes than those who experienced either adversity alone.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalArchives of Pediatrics and Adolescent Medicine·DateFeb 5, 2007

Two-thirds of nursing students believe it's wrong to lie to patients, twice as many as in 1983

A study published in the Journal of Advanced Nursing found that two-thirds of nursing students believe it's wrong to lie to patients, compared to 33% in 1983. The profile of nursing students has also changed significantly over 22 years, with older students, more diversity in educational attainments and life experiences.

SourceBlackwell Publishing Ltd.·JournalJournal of Advanced Nursing·DateFeb 5, 2007

Scripps research scientists: Compounds show significant promise against potential bioweapon toxins

Researchers identified two small molecules with remarkable efficacy against botulinum neurotoxin A in animal models. The compounds showed surprisingly little activity in cell-based assays, highlighting the importance of animal-based studies. No significant side effects were observed with either molecule.

SourceScripps Research Institute·JournalProceedings of the National Academy of Sciences·DateFeb 5, 2007

Survey identifies teen online behaviors associated with online interpersonal victimization

A recent study found that engaging in various online behaviors is linked to online interpersonal victimization, with talking to strangers being a significant risk factor. The survey analyzed data from over 1,400 teens and found that sharing personal info or making rude comments online were not as harmful as previously thought.

SourceJAMA Network·JournalArchives of Pediatrics and Adolescent Medicine·DateFeb 5, 2007

Microprinting technique for patterning single molecules

A new microcontact insertion printing technique builds surfaces with specific functions inserted at known intervals, enabling analysis of biochemical mixtures and molecular-scale electronic components. The process allows for precise placement of isolated molecules in a predesigned nano-scale or micro-scale pattern.

SourcePenn State·JournalApplied Physics Letters·DateFeb 5, 2007

Looking for love on all the right Web sites?

A recent study found that men systematically overestimated their height and women more commonly underestimated their weight on online dating profiles. The researchers also discovered that a higher percentage of participants lied about their weight, with almost two thirds being incorrect by 5 pounds or more.

For some species, an upside to inbreeding

Researchers found that individuals preferred mating with unfamiliar close kin rather than non-kin due to parental cooperation. This led to more cooperative and resource-invested parenting among related parents compared to non-related ones.

SourceCell Press·JournalCurrent Biology·DateFeb 5, 2007

SCAI expert panel sets high standards for PCI without on-site cardiac surgical backup

The Society for Cardiovascular Angiography and Interventions recommends stringent quality standards for PCI in hospitals without on-site cardiac surgery. These standards aim to ensure patient safety and excellent clinical outcomes, including case volume limits and training of support personnel.

SourceSociety for Cardiovascular Angiography and Interventions·JournalCatheterization and Cardiovascular Interventions·DateFeb 5, 2007