Researchers at Dana-Farber Cancer Institute found that boosting a key muscle gene improved Duchenne muscular dystrophy symptoms in mice. The study suggests increasing PGC-1alpha levels could slow or reduce disease progression.
Honeybees can learn to associate toxic odors with food and retain this ability for up to 24 hours. Researchers found that both sugar content and toxin levels affect a honeybee's memory for learned odours, suggesting they may have an innate ability to react to toxins.
The MARSIS radar has mapped the South Polar region of Mars, revealing a giant dome-shaped area composed mainly of ice. The radar signals have also identified depressions with variable distribution and depth of ice deposits at high latitudes.
French CNRS scientists have shown that a traumatic memory can be wiped out using a drug, while other associated recollections remain intact. This result could lead to the development of treatments for post-traumatic stress disorders.
Gérard Férey and his team at Institut Lavoisier have discovered a new family of trivalent metal dicarboxylates with unprecedented respiration properties, exceeding 300% volume variation upon solvent immersion. These crystalline solids possess reversible respiration mechanism without apparent bond rupture.
Researchers have identified the medial prefrontal cortex as a crucial region in storing and recalling social memories. This finding opens new perspectives on understanding human recollections and mental disorders affecting social skills.
Researchers at the University of Manchester discovered that nails are most resilient in humid environments with a relative humidity of 55-60%. This finding may help improve false nail and varnish products, reducing breakage and damage.
A recent study discovered that Egyptian fruit bats have a preference for certain sugars, including fructose and sucrose, to counteract the effects of ethanol toxicity. Consuming fructose-containing food resulted in faster decline of ethanol levels in their breath compared to other types of sugar.
Researchers discover telomere shortening as a predictor of coronary heart disease in pre-diabetics and Type 2 diabetics. Early indication of telomeres starting to shorten may indicate the onset of diabetes and ultimately predict CAD.
The French CNRS and CEA teams collaborated closely in constructing the LHC, assembling 392 quadripole magnets to guide beams through the tunnel. The technology developed during this collaboration is transferable to other equipment currently being studied or built.
Researchers identify PGC-1alpha as a key genetic component and potential therapeutic target for Duchenne muscular dystrophy. Experimental elevation of PGC-1alpha improves DMD symptoms in mouse models, offering new therapeutic promise.
Scientists at Rothamsted Research and University of Reading aim to decrease acrylamide formation by identifying its precursors. Low sulphur soils increase asparagine levels, leading to higher acrylamide production.
Scientists discovered that European Beewolf females deliberately cultivate bacteria in their antennae to shield their larvae from fungal infections. The bacteria produce antibiotics, significantly enhancing the larvae's chances of survival during hibernation.
Researchers are developing alternative culture methods to reduce the use of live fish in safety testing, reducing animal experimentation. Dr Richard Handy's perfusion method allows for the controlled exposure of fish organs to toxins, providing insights into toxicity and organ function.
Scientists have discovered a key enzyme controlling melatonin synthesis in response to light and darkness. The study sheds new light on the intricate mechanisms regulating our sleep-wake cycles.
Researchers have discovered that enhancing glyoxalase 1 levels can decrease glycation damage and extend lifespan in nematodes. The enzyme also protects proteins against oxidation and nitration, promoting healthy aging
The program, which teaches healthy habits and offers hope for a healthier future, has been successful in lowering diastolic blood pressure, total cholesterol, and LDL cholesterol levels among participants. With a significant drop in systolic blood pressures and blood glucose levels, the program aims to fight childhood obesity.
Danish researchers have shed light on how viruses, like HIV and bird flu, trick human cells into producing proteins needed for replication. They developed optical tweezers to investigate the mechanical unfolding of pseudoknots, a crucial step in virus replication.
A study by University of Manchester researchers reveals that arthritis pain activates the brain's emotional and fear centers, processing emotions and aversive conditioning. The findings suggest a more intense emotional response to arthritic pain compared to experimental pain.
Research by Dr. Anders Garm found that box jellyfish rely on intensity contrast, not color contrast, for obstacle avoidance. The lower lens eye plays a crucial role in detecting and responding to obstacles.
Scientists from Harvard University and the University of Pittsburgh found that carbon monoxide reduces or shuts down inflammatory responses by releasing chemical signals in mitochondria. This discovery raises hopes for developing new anti-inflammatory therapies, such as low levels of inhaled carbon monoxide.
Recent immigrants acquire English and lose Spanish rapidly, exhibiting levels of patriotism equal to native-born whites by the 3rd generation. Hispanics largely reject a purely ethnic identification and show high levels of commitment to work ethic.
Bifeprunox demonstrates a favorable weight and lipid profile, comparable to placebo, in patients with stable schizophrenia. The treatment also showed decreases in body weight and minor reductions in BMI in patients with acute exacerbations of schizophrenia.
Researchers found that fish in schools escape using a relatively fixed chronological order, indicating a potential leadership structure. This study was conducted at the International Marine Centre in Sardinia, Italy, and will be presented at the Annual Meeting of the Society for Experimental Biology.
A team of researchers from NIST and Northwestern University used advanced techniques to classify water in cement, distinguishing between physically bound and adsorbed water. This discovery has significant implications for predicting concrete properties and improving its durability.
Researchers from Sandia National Laboratories are conducting groundbreaking research at the North Slope of Alaska to better understand climate change. The team is studying how longwave energy gets trapped in the atmosphere, and their findings have significant implications for our understanding of Earth's natural energy balance.
A team of researchers has developed a technique to identify and structurally characterize glycans, assemblies of sugars attached to proteins on cancer cell surfaces, which may lead to the development of diagnostic tools or therapeutic agents specifically targeting them.
Researchers studied fruit flies and wasps, finding that they use most of the same genes with similar interactions, but with some modifications to accommodate developmental constraints. The study reveals the generality of developmental mechanisms across species, providing new insights into the workings of genetic pathways.
Scientists have identified a protein that excretes ammonia through pufferfish gills as similar to human Rh blood proteins, offering hope for people with liver and kidney disease. Targeting Rh proteins could lead to new treatments for removing toxic ammonia from the bloodstream.
Aging cells with dysfunctional telomeres can promote tumorigenesis, but p53-mediated senescence may suppress spontaneous cancer development. Activating the senescence pathway is sufficient to prevent tumorigenesis in mutant mice with dysfunctional telomeres.
A pilot study found significant correlations between copper and lead levels in sheep wool and local streams, suggesting that sheep wool can be a reliable bio-indicator of naturally occurring heavy metal concentrations. The study also revealed sex-specific differences in the accumulation of lead and copper in male sheep.
Researchers designed peptides that can bind to specific regions of transmembrane proteins to study their effects on crucial first steps in blood clotting. This breakthrough method allows for the interrogation of inaccessible proteins within the cell membrane.
New research highlights the impact of concurrent health problems on older adults, with 24% of Medicare beneficiaries aged 65+ and 31.4% of those 85+ having multiple comorbidities. The study aims to improve understanding of comorbidity and develop a comprehensive nosology for classification.
A study of 445 MS patients found that 29% prioritize medical treatment, while 19% seek socio-economic support, including household adaptations and transport provision. The researchers developed an MS satisfaction tool to assess quality of care and identify gaps in provision.
The study reveals that nanobubbles formed by the collapse of one bubble become new nucleation sites for later bubbles, allowing them to form earlier and at lower temperatures. This discovery may impact technologies such as inkjet printing and thermal cancer therapies.
Researchers at NIST found that short DNA-wrapped single-walled carbon nanotubes can selectively absorb into human lung cells, posing a potential health risk. The team's study suggests that the length of the nanotube plays a significant role in determining cellular uptake and toxicity.
A study led by Children's Hospital Boston found that lesbian/gay adolescents were three to four times more likely to report having been bullied than heterosexuals. The study analyzed data from over 7,500 adolescents aged 14 to 22 and found nearly half of the lesbian and gay youth had been bullied in the past year.
Researchers discovered a new cell type in pythons that degrades bone, allowing for efficient calcium absorption from prey.
A team of international scientists, including Case Western Reserve University's Matthew Sobel, has proposed eight ways to improve biodiversity forecasting in the face of global warming. The researchers aim to provide more accurate predictions and reduce misinformation that can divert resources away from other areas. By acknowledging th...
A new study confirms the US Census Bureau provided information on persons of Japanese ancestry to US surveillance agencies during WWII. The researchers call for the bureau to disavow its denials and set the record straight.
The AACR-Bardos Awards program offers financial support to third-year undergraduate students majoring in science, allowing them to attend the Annual Meeting 2007 and present their research. Winners also participate in the Undergraduate Student Caucus and Poster Competition.
Research found that estrogen improves host response after traumatic injury and decreases liver enzymes associated with damage. The study identified the critical cell surface receptor, GPR30, involved in estrogen's protective effects on the liver.
Researchers propose a novel method using ultraviolet light and titanium dioxide to cut proteins into manageable pieces for analysis. This technique offers advantages over conventional enzyme-based methods, including reduced sensitivity to temperature and acidity, ease of incorporation, and long-lasting material durability.
The American Association for Cancer Research (AACR) has awarded scholarships to 61 underrepresented scientists to participate in the AACR Annual Meeting. The awardees include early-career researchers from historically black colleges and universities, Hispanic-serving institutions, and tribal colleges and universities.
Researchers assessed female participants carrying different types of loads, finding that evenly spread loads are more efficient than awkward ones. This study supports the theory that early hominins carried children to adapt to walking on two legs.
The UCSD system uses a clever image indexing technique that allows it to cover larger collections of images at a lower computational cost. It outperforms existing approaches in terms of annotation and retrieval accuracy, as well as efficiency.
A Sandia National Laboratories handheld device determines if a patient has gum disease and quantifies its advancement in minutes from a tiny saliva sample. The device's technology also shows promise for detecting biotoxins, improving prostate and breast cancer diagnosis, and measuring animal serum in vaccines.
A new device created by MIT researchers allows biologists to physically arrange cells to be touching, close but not touching, or completely separated. This enables researchers to study cell interactions and changes over time without breaching the divide, leading to insights into liver cell differentiation and cancer.
A study found that overfishing large sharks leads to an explosion of their ray and skate prey species, which in turn devastates scallop populations. The decline of great sharks has triggered cascading effects throughout coastal food webs, impacting local communities that depend on healthy fisheries.
LCT reports a major breakthrough in islet transplantation, with a human patient showing evidence of live porcine islet cells and insulin production ten years after the transplant. The study demonstrates the long-term safety and viability of LCT's encapsulated porcine islets without immunosuppression.
Evo-devo researchers are urging scientists to select new model organisms based on their ability to shed light on specific evolutionary themes, rather than just phylogenetic position. The current choice of model organisms has been criticized for being too narrow and not representative of the diversity of life on Earth.
Astronomers have described the double asteroid Antiope in unprecedented detail, revealing its unique orbit and shape. The asteroid consists of two rubble-pile chunks of material, tidally locked and rotating around each other at the same speed as they orbit.
Researchers at the University of Illinois have discovered a technique to make metal memory, allowing metals to revert to their original shapes when heated. The discovery could lead to vanishing dents and other physical feats.
Research suggests that exclusive breastfeeding significantly lowers a baby's risk of postnatal infection with HIV. In contrast, introducing animal milks and solid foods before 14 weeks increases the risk. The study's findings warrant a revision of current infant-feeding guidelines.
Scientists discovered a protein that enables cells to bypass damaged DNA during replication, averting cell suicide. However, this protein also makes errors that may contribute to the development of cancer.
A team of Princeton University chemists has discovered a new method to synthesize molecules without toxic catalysts, reducing the risk of hazardous barriers in drug development. This breakthrough opens up new possibilities for working with ketones and aldehydes, potentially leading to more efficient synthesis of beneficial enantiomers.
Researchers at the Salk Institute discovered that GUN1, a nuclear-encoded protein, plays a crucial role in transmitting distress signals from damaged chloroplasts to the nucleus, triggering a shutdown of photosynthetic genes. This finding sheds light on the complex communication between organelles and the nucleus.
Researchers at the University of Manchester found that older women with breast cancer receive lower levels of care compared to younger women. This includes reduced likelihoods of needle biopsy, surgery, and radiotherapy, which can lead to higher local recurrence rates and mortality.
A study found that leisure-time physical activity is associated with a lower risk of work-related repetitive strain injury. The researchers analyzed data from the Canadian Community Health Survey and discovered that being physically active during free time can protect against this type of injury.
Researchers at UCSD School of Medicine discovered a cellular receptor involved in triggering cell death is also necessary for tissue repair and regeneration after liver injury. p75 neurotrophin receptor promotes the initial activation of hepatic stellate cells to stimulate new hepatic cell proliferation.