Researchers found that reactive oxygen stimulates dendritic cells to up-regulate the immune antigen CD80, leading to T cell activation and increased TNF production. This causes excessive destruction of bone via osteoclasts.
Researchers at UW-Madison developed a novel enzyme that can decorate chemical molecules with natural sugars, altering their biological effects. The new enzyme has the potential to create a range of therapeutic agents for cancer treatment and infection prevention.
Researchers found humans carry more gene copies than ape relatives to produce more amylase enzyme, which digests starch. This discovery bolsters the idea that starch played a crucial role in early human diet and evolution.
Scientists have identified unique stem cells within adult tendons that can proliferate and self-renew, regenerating tendon-like tissue in an animal model. This breakthrough could lead to the development of new treatments for tendon injuries caused by overuse and trauma.
The study reveals a novel function for COUP-TF1 in balancing the sizes of functional areas in the brain, ensuring proper partitioning into 'frontal' areas controlling emotions and movements versus sensory areas interpreting the environment. This discovery may explain individual differences in behavior and skills.
The probe, which binds to active proteases in cancerous cells, beams out near-infrared light that passes through skin and is detectable with a special camera. The technique has the potential to provide a less harmful method of detecting cancer, especially in early stages.
Researchers have made significant discoveries in the AGU journal, including a new understanding of booming sand dunes, a reduction in the North Asian monsoon's incursion since AD 1400, and improvements in global ocean analysis. The study on booming sand dunes reveals that sound waves channeled through the dune amplify as they construct...
Tulane University will receive $14 million to train public health workers and establish monitoring systems in Ethiopia, while also supporting programs in Haiti, Brazil, South Africa, and other high-risk countries. The grant aims to rebuild infrastructure and combat the spread of HIV/AIDS in these countries.
A Harvard study found that socioeconomic status influences antiretroviral treatment effectiveness, even among those adhering to treatment schedules. Lower education levels were associated with faster regimen failure, while higher adherence self-efficacy reduced this risk.
A study from the University of Pittsburgh Schools of the Health Sciences found that maternal vitamin D deficiency early in pregnancy is associated with a five-fold increased risk of preeclampsia. Low vitamin D levels also affect newborns, increasing their risk of mortality.
A good reception year teacher makes a significant difference in primary school education, with cumulative effects throughout the years. The study found that early years education is critical for children's later cognitive development, and focusing on these years can yield long-term gains.
Gene therapy holds great promise but faces safety concerns due to virus-based delivery methods. MIT researchers have created biodegradable polymers that can deliver genes safely and effectively, showing promise for ovarian cancer treatment and other applications.
A ventilation/perfusion lung scan (V/Q scan) is a reliable alternative to CT angiograms in diagnosing pulmonary embolisms, especially in young women. The study found that V/Q scans can exclude pulmonary embolism with low probability clinical assessment, reducing radiation exposure and breast cancer risk.
Researchers found that prion infection influences the expression of endogenous retroviruses in mouse cells, with some sequences increasing and others decreasing. The effects could be suppressed by an anti-prion drug, suggesting a possible link between prions and retrovirus production.
Researchers at UT Southwestern Medical Center created a mouse model of autism, exhibiting poor social skills but enhanced mental abilities, akin to Rain Man's character traits. The study reveals an imbalance in inhibitory brain action and suggests focusing on this aspect for treatment.
The Consortium for Neuropsychiatric Phenomics aims to understand the biology underlying various mental disorders by targeting healthy brain systems, such as memory and impulse control. This interdisciplinary approach may lead to new treatments and accelerate gene discovery.
A national team of scientists is investigating fertility preservation for women with cancer through the $20 million program. MU researcher John Critser will receive funding to study cryopreservation methods of human eggs, aiming to improve efficiency and challenges in the process.
A new study confirms that colour contrast is first detected by the primary visual cortex at the back of the brain. The brain processes colour contrast earlier than previously thought, making it a significant contribution to understanding how the brain functions.
Sulfur and nitrogen emissions from power plants and agricultural activities significantly impact coastal ocean chemistry, reducing its ability to store carbon and harming marine life. The study found that these emissions can alter water chemistry by 10-50% more than acidification caused by carbon dioxide.
The Society of Nuclear Medicine and Molecular Imaging has revised its nuclear medicine technologist's scope of practice, reflecting changes in technology and molecular imaging. The updated document includes procedures such as CT scans and administering contrast.
A new study by Hopkins researchers reveals that the DISC1 protein plays a critical role in guiding newly made nerve cells into the brain's neural network, allowing them to integrate seamlessly. Abnormalities in this process may contribute to psychiatric disorders like schizophrenia.
A new study published in Management Insights reveals that online auctions where all bids are disclosed after the bidding round benefit buyers. The research finds that buyers pay higher prices when only winning bids are disclosed, leading to better outcomes for consumers.
Postmenopausal women consuming two or more alcoholic beverages daily may double their risk of endometrial cancer, according to a USC study. The study found that lean women are more sensitive to alcohol's effects on hormone levels, increasing their cancer risk.
The American Gastroenterological Association has established minimum standards for gastroenterologist performance of CT colonography, requiring at least 75 endoscopically confirmed cases to be interpreted. The guidelines emphasize the importance of training and quality control to ensure accurate screening for colorectal cancer.
A new study from Vanderbilt University predicts the future career path of gifted youth can be identified by their performance on the SAT at age 13. The study found significant differences in creative and career paths among individuals with different ability patterns on the math and verbal portions of the test.
A new study is providing highly successful parenting skills to parents with bipolar disorder, using the Triple P Positive Parenting Programme. The program has been shown to improve behavior in children and increase parental confidence, particularly for those experiencing instability of mood and behavior.
A study published in Science found that toddlers outperform apes in understanding nonverbal communications, imitating solutions to problems, and understanding intentions of others. The research suggests that humans have distinctive social cognitive skills that allow them to excel in cultural groups.
The Oncofertility Consortium seeks to alter the medical world's approach to female cancer patients, promoting a new consciousness to protect their reproductive health. Researchers will investigate fertility threats posed by cancer treatment and develop strategies to improve communication with newly diagnosed patients.
Researchers found beta blockers to be more effective and safer than banding in reducing the risk of variceal bleeding in cirrhotic patients. The study, published in Liver Transplantation, compared the two treatments and found that beta blockers lowered the risk of bleeding by over 90%, while banding reduced the risk by less than 70%.
Depression produces the greatest decrement in health compared to chronic diseases like angina, arthritis, and asthma. People with depression and one or more chronic diseases have the worst health scores, according to a study of 245,404 people.
The Lancet highlights the lack of accountability for medical professionals involved in torture at Guantanamo Bay, despite the Royal College of Physicians' condemnation of force-feeding as a criminal act. Doctors accused of negligence and unethical behavior have yet to face charges or convictions.
A study of 100,000 pregnant Norwegian women found an unexpected increase in new cases of binge eating disorder during pregnancy. The research suggests that adequate prenatal care and nutritional support are crucial to prevent the development of disordered eating behaviors.
A team of researchers has found a strong correlation between Israeli Acute Paralysis Virus (IAPV) genetic material and Colony Collapse Disorder (CCD) in bees. The prevalence of IAPV, the timing of outbreaks, and geographical circumstances suggest that IAPV is a significant marker for CCD.
Researchers have found that three major classes of antibiotics work by ramping up harmful free radicals in bacteria, making existing antibiotics less effective. This discovery could lead to new classes of antibiotics and improved methods for treating resistant infections.
A study published in PLoS Computational Biology found that the number of memories stored in the brain is limited by the number of connections between neurons, not the number of neurons. This means that a typical human brain can store at most about 500 memories, regardless of its size.
The NIH Roadmap for Medical Research is launching nine interdisciplinary research consortia to foster collaboration across multiple disciplines, addressing resistant health challenges. The program aims to transform academic research culture and provide a stimulus for academic research change.
A team of researchers, including Arizona State University's Gro Amdam, has discovered that the Polistes wasp's larval environment determines its future royal stature through environmental cues. The study sheds light on how developmental diapause and reproduction can be adopted in primitively social settings to result in complex social ...
The National Research Council recommends pursuing the Joint Dark Energy Mission as the first mission in the 'Beyond Einstein' program, which aims to study dark energy. The report also suggests investing additional funds in technology development of the Laser Interferometer Space Antenna (LISA) program.
A study reveals that the DISC1 gene directs the incorporation of new neurons into the adult brain, regulating their process under control. Reduced DISC1 levels in mice led to accelerated integration of neurons into existing brain circuitry, resulting in abnormal neural function.
Researchers at the University of Texas M. D. Anderson Cancer Center found that congestive heart failure is rare among leukemia patients taking imatinib. Only 22 out of 1,276 patients developed symptoms that could be caused by heart failure, and most had underlying medical conditions that also contributed to their condition.
A global survey found that fewer people in less developed countries with mental disorders sought services compared to those in high-income countries. The U.S. population used services the most at 18%, while Nigeria had the lowest rate at 1.6%.
Researchers discover Israeli Acute Paralysis Virus (IAPV) significantly associated with colony collapse disorder (CCD) in honey bee colonies. IAPV was found in all four affected operations and correctly distinguished CCD from non-CCD status 96.1% of the time.
Researchers found that heat stress, measured by temperature-humidity index (THI), was a significant factor in low conception rates of dairy herds. High THI values before insemination, particularly on Day 3, led to ovulation failure and reduced fertility. Conversely, cooling measures implemented when temperatures exceeded 20°C improved ...
The Northwest Genome Engineering Consortium will develop methods for gene repair using multiple scientific disciplines. The goal is to improve treatments for genetic diseases affecting blood stem cells, a major global disease burden in children.
New evidence from a tiny Mongolian dinosaur suggests that small size evolved before flight in dinosaurs, forcing paleontologists to re-examine their assumptions about the evolution of birds. The study found that some dinosaur lineages actually increased in size over time, contradicting previous theories.
Researchers at Boston University have found a previously unknown chain of events in bacteria that opens the door to new avenues of research. The team discovered a common process triggered by all three types of antibiotics, resulting in excessive free radical production that can be amplified or weakened to enhance lethality.
The American Society of Plant Biologists awarded Fellow of ASPB, Adolph E. Gude, Jr., Award, Charles Albert Shull Award, Charles Reid Barnes Life Membership Award, Corresponding Membership Award, Excellence in Teaching Award, and Martin Gibbs Medal to distinguished researchers and educators in plant biology.
A new turbulence detection system using NEXRAD Doppler radars provides real-time snapshots of turbulence to pilots, helping them avoid hazardous areas. The system's accuracy is reported to be high, with pilots praising its ability to provide accurate information about turbulence location and intensity.
A UCR plant cell biologist is studying how plant stem cells maintain their identity and specialize into different cell types. He will use two powerful methods, microgenomics and live imaging, to understand the molecular and cellular mechanisms behind stem-cell regulation.
Scientists at Massachusetts General Hospital found that the Foxn1 gene determines where pigment is deposited in the epidermis and hair. The study reveals that melanocytes deliver melanin to specific cells indicated by the Foxn1 gene, which acts as a map for pigment distribution.
Researchers found that the human immune system uses hemoglobin to bind to HDL and create a toxin that clears trypanosomes from the body. This discovery could lead to better treatment options for cattle infections and provide insights into understanding why some parasites don't infect humans.
Researchers are developing robotic instruments that can navigate the chambers of the heart through needle-sized incisions and deploy tools to remove blockages, repair faulty valves and close leaks while the heart is still beating.
Researchers identified a virus, Israeli Acute Paralysis Virus (IAPV), as a leading candidate in the deaths of tens of billions of bees. The study found that IAPV was only present in collapsed colonies, suggesting a possible causal relationship between infection and Colony Collapse Disorder.
The new journal Stem Cell Research will cover all aspects of stem cell research, including embryonic stem cells, cancer stem cells, and developmental studies. It aims to disseminate the results of ongoing research in this rapidly expanding field, with a focus on high-quality peer-reviewed studies.
The team's new e-jet printing process can produce lines as narrow as 700 nanometers and dots as small as 250 nanometers using electrically induced fluid flow and nanoscale nozzles. This technology has potential applications in large-area circuits, displays, photovoltaic modules, security, biotechnology, and photonics.
Research in African monkeys reveals that CD4 T-cell depletion is one part of a complex scenario leading to AIDS. Studies suggest that immune function can be preserved despite significant loss of mucosal CD4 T-cells.
Researchers discovered that soy isoflavone genistin significantly reduced rotavirus infectivity by 33-74%, with the active component being genistin alone. The study found an effective range of concentrations, and the results held up even in high levels of rotavirus exposure.
A new study by Harvard researchers found that non-human primates infer intentions based on rational action, not just surface-level appearances. The primates chose the most accessible food container in each scenario, demonstrating a human-like understanding of others' goals and actions.
The AAAS project aims to provide a science-based understanding of alcohol's effects on the body, focusing on key scientific concepts and recent advances in neuroscience. The initiative will offer students and teachers a comprehensive resource for teaching and learning about underage drinking.
Existing technology and resources can solve cervical cancer's global burden, especially in developing countries. The disease disproportionately affects women worldwide, particularly in regions with limited resources.