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Science News for July 18, 2008


Averting postsurgical infections in kids: Give antibiotics within hour before first incision

A Johns Hopkins study found that giving children preventive antibiotics within one hour of spinal surgery significantly reduces the risk of serious infections. The study, published in Pediatric Infectious Disease Journal, suggests that timely prophylaxis is crucial in preventing complications and reducing hospital stays.

SourceJohns Hopkins Medicine·JournalThe Pediatric Infectious Disease Journal·DateJul 18, 2008

CSHL scientists correlate enzyme expression levels with chemotherapy drug response

Researchers at Cold Spring Harbor Laboratory have identified Top2A and Top1 enzymes as significant contributors to chemotherapy drug resistance. The team developed a novel screening technique to investigate the genetic basis of cancer therapy response, which could be applied widely to explore genetic mechanisms underlying drug resistance.

SourceCold Spring Harbor Laboratory·JournalProceedings of the National Academy of Sciences·DateJul 18, 2008

Molecular hula hoop

Japanese researchers successfully observed individual molecular rotors caught in motion using a novel microscopy technique. The study focused on rotaxanes, two-part molecular systems that rotate around an axis, revealing rapid rotational and vibrational motion when wet.

SourceWiley·DateJul 18, 2008

Standards in stem cell research

New research funded by the Economic and Social Research Council explores standards in stem cell research, balancing scientist autonomy with data comparability. The study suggests that standardizing practices could lead to automation technologies, but also raises concerns about exclusivity and robustness.