A Japanese research group identified the PKD1L3-PKD2L1 channel complex as a key player in the sour taste sensation. This 'off-response' mechanism allows humans to detect sour flavors even after the removal of acidic stimuli.
Researchers at Rush University Medical Center present pre-clinical data on a CD26 Inhibitor that increases the efficiency and responsiveness of umbilical cord blood for bone marrow transplants. The technology may improve treatment outcomes for blood cancer patients who require stem cell transplantation.
The American Heart Association recommends modifying lifestyle factors such as reducing salt intake, losing weight, and drinking less alcohol to treat resistant hypertension. Effective treatment also requires better diagnosis of secondary causes and effective use of multiple-drug treatments, including long-acting diuretics and mineraloc...
Researchers found that patients who gained weight over time had lower mortality rates, suggesting that a reasonable amount of weight gain may be a sign of adequate insulin control. The study also found no significant difference in mortality between those with an overweight or normal BMI and those with an underweight BMI.
Researchers have found that adult stem cells from Parkinson's patients' noses can differentiate into dopamine-producing brain cells when transplanted into the brain of a rat. This breakthrough has significant implications for treating the debilitating symptoms of Parkinson's disease.
A new study reveals that short-wavelength light, like natural blue sky light, is highly effective at stimulating the human circadian system. Exposure to multiple wavelengths of light simultaneously can result in less total stimulation compared to viewing individual colors separately, a phenomenon known as spectral opponency.
Researchers at USC have identified a novel genetic association between fasting glucose levels and melatonin receptor 1B (MTNR1B), increasing the risk for type 2 diabetes. The study found a connection between MTNR1B and circadian rhythm regulation, suggesting potential links to sleep disorders.
A new review suggests that participants' desire for transparency outweighs bioethicists' concerns about potential negative psychological consequences. Volunteers generally want access to aggregate study results and some individual results if relevant to their lives. However, individual results can be overwhelming and expensive to provide.
A new technology developed by University of Leeds engineers can monitor crystals as they form in drug manufacture, providing a method to ensure production of desired drug compounds. This can lead to huge delays and costly challenges for drug companies, but the technology has enormous commercial potential.
A study by Dr. Iain Edgar at Durham University found that militant jihadists often legitimize their actions based on night dreams and connect to a mythical past through these dreams. The research also highlights the significance of understanding night dreams as a tool to assess one's worldview and implicit motivations.
Scientists gather to present research on using mechanics to study and explain biology, highlighting the role of faint pushes and pulls in cellular signaling. The symposium aims to develop fundamental math and mechanics to understand biological processes like embryo development and growth.
A Saint Louis University study found that patients with advanced heart failure may not benefit from implantable cardiac devices due to their underlying illness. The researchers identified two red flags: prolonged hospitalization and use of inotropic therapy, which are associated with higher risk of in-hospital mortality.
Brazil is transitioning from imitator to innovator in health-related products, with several small and medium-sized enterprises succeeding in developing innovative products. Despite facing challenges such as regulatory barriers and limited access to private equity, Brazil's biotech industry has the scientific capacity to become a major ...
Scientists at Schepens Eye Research Institute have identified specific molecules that awaken dormant brain stem cells, which can transform into neurons and repair damaged brain tissue. The findings suggest that tapping the brain's regenerative potential may be a promising approach for treating neurodegenerative diseases.
Researchers have discovered that the brain uses a forward model to generate predictions about future movements, allowing for rapid and accurate control. This breakthrough has significant implications for the development of neural prosthetic devices and could one day enable people with paralysis to control their limbs through thought.
The University of Southern California has been awarded $12.4 million to spearhead a rehabilitation project for stroke survivors. The study, named I-CARE, aims to optimize rehabilitation therapies to improve patient quality of life.
A recent study suggests that serotonin levels affect our sense of fairness, leading to increased impulsivity and aggression when unfair offers are made. The findings may help explain social difficulties associated with disorders like depression and obsessive-compulsive disorder.
Public attitudes toward embryonic stem cell research are influenced more by religious values and deference to scientific authority than scientific knowledge. For highly religious audiences, understanding the science has no effect on their views, while for less religious individuals, it is linked to more positive attitudes.
New research from Brandeis University finds that multi-tiered formularies requiring higher copayments for non-preferred medications reduce the use of antidepressants. The study, which analyzed data from a large nonprofit managed care organization, found that out-of-pocket spending increased while health plan spending per user decreased.
Two IEEE-USA Engineering Mass Media Fellows are writing news stories on science and technology for top California newspapers. The program aims to improve public understanding of STEM fields through clear communication.
Scientists at Savannah River National Laboratory developed Glass Microspheres with porous walls that can store hydrogen gas and release it safely. These microspheres can also be used to filter mixed gas streams and are suitable for reuse and recycling due to their unique mechanical properties.
A new study by UC researchers suggests that cases of Amyotrophic Lateral Sclerosis (ALS) among soldiers who served in the first Persian Gulf War were caused by specific events, with a declining risk after 1996.
Researchers found that intensively lowering blood sugar to near-normal levels did not significantly reduce the risk of major cardiovascular events, but increased the risk of death. The intensive strategy group had a 22% higher risk of death compared to the standard group.
Researchers at University of Missouri use tree rings to determine that massive wildfires in Canada caused the infamous 'New England Dark Day' in 1780. The study combines written accounts and fire scar evidence to provide a scientific explanation for this mysterious event.
A recent study conducted by researchers at Qilu Hospital of Shandong University used 3T MRI to stage and plan sphincter-sparing surgery for patients with rectal cancer. The study found that MRI accurately identified 31 of 32 resectable cases, contributing to precise surgical planning.