Researchers at CAMH have detected evidence that DNA is not the only carrier of heritable information, with epigenetic factors playing a significant role. This finding challenges traditional genetics principles and may provide new insights into human disease causes.
Researchers investigated the mechanisms behind reduced gastric mucosal blood flow caused by H. pylori extracts, finding a nerve- and iNOS-mediated pathway involved. The study revealed that H. pylori extracts decrease gastric mucosal blood flow by approximately 30% in mice.
Research in Costa Rica found that H. pylori infection, particularly the status of cagA and vacA genotype distribution, plays a major role in gastric cancer incidence rate variability. Gastric atrophy and intestinal metaplasia were more common in patients with high GCIR.
A genetic study found that 4% of Indian subcontinent populations carry a MYBPC3 mutation, associated with a high risk of heart problems. Researchers identify a potential solution through early screening and lifestyle modifications.
A study found that most gene switch sites occur on nearby regions, called CpG shores, not just isolated DNA islands in the human genome. This discovery has significant implications for understanding disease and developing new treatments against colon cancer.
A study found that HCC cases with AIH and PBC have four clinical features: shorter survival intervals, more men affected, and liver failure as primary cause of death. The research highlights these common characteristics in HCC associated with AIH and PBC.
Researchers have identified a crucial biochemical step involved in nerve cells' response to DNA damage. Cdk5 activation is necessary before ATM can function in neurons, suggesting it as a potential drug target for neurodegenerative diseases. This discovery sheds light on the underlying mechanisms of ataxia telangiectasia and other neur...
New research reveals a connection between water pollution and declining male fertility, with anti-androgenic chemicals identified as key players. The study suggests that exposure to these chemicals may contribute to reproductive problems in humans, particularly those affected by testicular dysgenesis syndrome.
A new study reveals three genetic variations that increase the risk of severe obesity in children, with potential for early intervention and prevention. The gene variants may account for up to half of all cases of adult and child obesity.
Researchers discovered that long stretches of DNA containing many genes are silenced in cells as they mature, rather than individual genes. This epigenetic modification, called LOCKS, plays a crucial role in cell differentiation and development.
The special issue highlights various new treatment options, including mobile phones, Internet-based interventions, and computers. Researchers have seen promising results, such as a high number of students logging on to screening programs and increased access for hard-to-reach populations.
Ascent to high altitudes causes a range of effects on the brain, including headaches, eye hemorrhages, and sleep disruptions. Research suggests that genetic predisposition, factors such as hypoxia-inducible factor, and venous system play a role in susceptibility to altitude-related illnesses.
A Montreal-based research team has identified a new mechanism controlling NK cell activity, which could improve the treatment of cancers and infectious diseases. The team's breakthrough discovery reveals that the CRACC molecule enhances NK cell killer function.
University of Florida researchers develop a new approach to lab-on-a-chip technology by harnessing biologically powered molecular forklifts. This innovation allows for the creation of 'smart dust' that can detect biological threats and other contaminants without the need for electricity or rinsing.