A gene variant has been linked to an increased risk of developing brain tumors at a younger age, with 20.6% of young people with glioblastoma multiforme having the Pro/Pro variant of the TP53 gene compared to 5.9% of healthy participants.
A new study has identified certain patient and tumor characteristics that may indicate which breast cancer patients are at high risk of developing contralateral breast cancer. These include histologic invasive characteristics, multiple quadrants affected, and a high Gail risk score or age over 50 at diagnosis.
Scientists at Lawrence Livermore National Laboratory and the University of Illinois have determined the temperature at which helium becomes insoluble in dense metallic hydrogen. This finding has significant implications for models of the interior structure and evolution of Jovian planets, including Saturn and Jupiter.
Researchers at UT Southwestern Medical Center identified a compound that liberates cholesterol trapped in cells, shedding light on its transport and suggesting a possible therapeutic target for NP-C disease. The findings show improved liver function and decreased neurodegeneration in mice treated with the compound.
Climate change and sea ice fluctuations threaten emperor penguin populations, with a median colony size predicted to decline from 3,000 to 400 breeding pairs. The probability of drastic decline is at least 40%, putting the species at risk of extinction.
Researchers studying astronauts on the International Space Station found a greater rate of bone deterioration than previously thought. Astronauts experienced an average loss of 14% hipbone strength, comparable to those with osteoporosis.
Shoulder injuries accounted for 8% of all injuries in high school athletes, with boys experiencing higher rates than girls. Player-to-player contact was associated with nearly 60% of shoulder injuries across sports.
Researchers from Université de Montréal have detected chemotherapy products and hypertension/cholesterol medications in wastewater released into the St. Lawrence River. The study highlights a growing concern about pharmaceutical waste's impact on the environment, with minimal quantities of these substances present in treated water.
A study of over 800 men found that those who were very sexually active in their twenties and thirties were more likely to develop prostate cancer, especially if they masturbated frequently. However, the risks diminished with age, particularly in a man's fifties.
A study of third-graders found that daily recess improved classroom behavior, social development, and health. Children who received more recess behaved better and were likely to learn more.
Researchers have discovered that the innate immune system's natural killer cells can learn from experience and fight more effectively when called into battle a second time. This new ability, known as 'memory-like,' was found in natural killer cells that could respond more easily and vigorously to reactivation.
A recent study from the University of Michigan found that six million US children have unmet medical needs, with uninsured and underinsured children at highest risk. The study highlights the need for targeted initiatives to address both coverage and access to improve healthcare outcomes for vulnerable children.
Researchers at UAB found that children who use cell phones while crossing streets are more likely to exhibit risky behaviors, including taking longer to cross and looking both ways less often. The study's findings highlight the need for parents and caregivers to limit cell phone use in child pedestrians.
A new study by Nicole Votolato Montgomery and H. Rao Unnava found that consumers tend to favor vacations with improved outcomes over those with worsened outcomes when evaluated immediately, but reverse preferences emerge after a delay.
A new study reveals that non-food factors such as swimming and private well water exposure pose significant risks for sporadic bacterial enteric infections, comparable to food-borne risk factors. The findings highlight the importance of controlling these environmental exposures to prevent outbreaks.
The new journal Genomic Medicine bridges the gap between research and clinical practice, providing open access to high-quality research articles. The journal features columns by leading experts on genomic medicine and its applications.
Researchers have demonstrated that gene therapy can reduce pain and swelling in patients with advanced rheumatoid arthritis. The therapy involves implanting a normal gene to compensate for a defective gene, resulting in lower amounts of disease-related proteins and reduced symptoms.
New research published today disproves the recent comet impact theory that triggered continent-wide wildfires in North America 12,900 years ago. The study found no evidence for large-scale fires across the continent but supports a link between global warming and increased wildfires globally.
A study by Rachel Smallman and Neal J. Roese found that people with positive preferences sort items into finer, more specific categories compared to those with negative preferences. This suggests that our likes can shape how we categorize information, particularly in consumer psychology where this can influence brand perceptions.
New photoactivatable fluorescent proteins (PAFPs) and advanced fluorescent proteins (FPs) allow scientists to visualize individual cellular molecules in living cells. These tools are transforming biomedical research by enabling the study of cancer cells, protein-protein interactions, and cellular processes.
Researchers have discovered DNA hotspots associated with psoriasis, an autoimmune disease characterized by skin patches and joint pain. The study identified four novel genes linked to the condition, providing potential targets for new treatments.
Lifetime risk of alcohol-use disorders for men exceeds 20% and women less than half that, with 15% at risk for abuse and 10% for dependence. Effective recovery strategies exist and can begin with doctor visits.
Unchecked global warming would lead to a dramatic expansion of low-oxygen areas in the ocean, affecting fisheries and ecosystems for thousands of years. The team's projections show that these oxygen minimum zones could expand much more still and invade the deep ocean.
Researchers found that rapid-fire inputs initiate a cellular memory process in single cells lasting as long as a minute, holding moment-to-moment information. The study has implications for addiction, attention disorders and stress-related memory loss.
Scientists have found a genetic variant within the LCE gene cluster that provides protection against psoriasis. This discovery suggests compromised skin barrier function plays a role in the disease's development.
A genome-wide study in yeast redefines the concept of promoters, showing most regions produce overlapping transcripts starting at the same promoter. This finding has implications for understanding gene expression and regulation in humans.
A new study aims to determine whether consuming caffeine during pregnancy can increase the unborn baby's risk of developing childhood leukemia. The research, led by Dr. Marcus Cooke, will examine DNA changes in newborn babies and compare them to caffeine consumption levels.
A new psychodynamic approach, CAPSLE, focuses on empathy and power dynamics to reduce children's experiences of aggression and improve classroom behavior. The study found that schools implementing CAPSLE reported fewer aggressive incidents and more positive bystanding behaviors.
A new study uses airborne technology to track changes in Big Island tropical forests, revealing how climate and invasive species affect carbon stocks. The research finds that fast-growing invaders decrease biomass levels, while slower-growing species increase biomass stocks.
Only about one-tenth of unemployed workers secure COBRA coverage, leaving millions at risk due to unaffordable premiums. Low-wage workers are disproportionately affected, with limited public coverage options, and policymakers should consider expanding Medicaid eligibility to provide critical support.
Researchers at Oklahoma State University have made a significant breakthrough in understanding how poxviruses evade the human immune system. By unlocking the structure of a key protein, they may be able to design medications to stop the viruses from blocking immune signals.
Research finds children with newly diagnosed IBD have higher concentrations of folate in their blood compared to individuals without the disease. This discovery challenges previous theories on folate deficiency in IBD patients.
Scientists at Emory University School of Medicine have found a way to block the toxic effects of tPA, a life-saving clot-busting drug used in acute stroke treatment. By blocking LRP1, a molecule that transmits inflammation signals triggered by tPA, the researchers were able to soften the drug's impact on the brain.
Researchers find that stretching facial skin during speech affects perceived sound, linking production and perception. The study contributes to understanding the relationship between speech perception and production.
Mortality rates for acute respiratory distress syndrome (ARDS) have remained relatively stable since 1994, with a benchmark mortality of 40-45% according to a comprehensive review of major studies. The findings highlight the need for effective therapeutic interventions for this highly lethal syndrome.
A team of researchers at CIC nanoGUNE and Max Planck Institutes developed a non-invasive method to map strain fields in semiconductors using scattering-type Scanning Near-field Optical Microscopy (s-SNOM). The technique resolves nanoscale material properties with 20 nm spatial resolution.
A new study at Brigham Young University found that young adults' video game use is associated with poorer relationships with peers and parents. The study, which analyzed data from 813 college students, suggests that excessive gaming may lead to decreased social interaction and relationship quality.
Kristine C. Harper's 2008 book, 'Weather by the Numbers: The Genesis of Modern Meteorology,' has received international acclaim from atmospheric science librarians. The book explores the transformation of meteorology from an art to a scientific discipline, highlighting the development of numerical weather prediction and its impact on w...
Lung airway epithelial cells initiate an immune response to inhaled bacteria by signaling white blood cells to move into the lungs. Researchers have identified a way to inhibit proteases and restrict junctions between cells, reducing inflammation and allowing optimal white blood cell response.
A New York University study suggests that registered nurses with a second degree are an efficient solution to the current nursing shortage. Second degree nurses tend to be older and more motivated, having coping advantages over newer graduates, which can lead to better job satisfaction and retention rates.
A new strategy developed at Nationwide Children's Hospital is helping premature infants and newborns with severe swallowing difficulties learn to feed on their own. The approach involves individualized, crib-side studies that use advanced sensors to capture the rhythm of muscular contractions throughout the aero-digestive tract.
Researchers found that stable nanoclusters of calcium carbonate form in water with a small quantity of dissolved calcium carbonate, not as previously thought. This discovery may help explain the structure of biominerals and provide insights into coping with lime scale in washing machines.
A Purdue University researcher used a process focusing on one gene to trace the evolutionary history of domesticated rice, discovering genetic variation over millions of years. By comparing domesticated plants to wild rice species, scientists can identify valuable genes for desirable traits like branching and increased plant size.
Researchers have discovered a novel way in which the Myc oncogene accelerates cancer by directly affecting protein production, suggesting a new strategy to halt cancer's progression. Drugs like Rapamycin may help treat cancers where Myc is overactive.
Researchers at UC Riverside have designed a catalyst that allows for the production of partially hydrogenated oils while minimizing the formation of trans fats. By controlling the shape of platinum particles, they achieved higher selectivity and reduced the creation of harmful trans fats.
A study published in Pediatrics found that telemedicine can significantly improve the quality of child sexual assault examinations in rural communities. The use of videoconferencing allows experts to guide local doctors, comfort children, and enhance the collection of forensic evidence. As a result, many physicians changed their examin...
A recent study found that fainting was the most common in-flight medical emergency, accounting for 53.5% of cases. The researchers also highlighted the need for standardization in reporting in-flight emergencies, citing poor data quality as a major issue.
A therapy developed at UC Irvine will become the world's first embryonic stem cell treatment tested in humans, targeting patients with acute spinal cord injury. The U.S. FDA has approved a clinical trial led by Geron Corp., which aims to restore electrical conduction and mobility in paralyzed individuals.
Researchers at Berkeley Lab and Cal Tech have created a high-Q surface-plasmon-polariton whispering-gallery microcavity, enabling ultra-small device fabrication and strong light enhancement. This innovation paves the way for future nanolasers with applications in photonics and optical microchips.
A study found that sleep apnea is strongly associated with decreased glucose metabolism and pancreatic function, independent of body fat. Another study linked chronic intermittent hypoxia from sleep apnea to liver disease progression in severely obese patients.
The University of Texas at San Antonio has received a $1.2 million gift to purchase an aberration-corrected electron microscope, one of only two worldwide. This instrument will aid researchers in developing new cancer therapies and treatments, while also advancing research globally across various disciplines.
Research by Northern Arizona University ties tree mortality to climate change, with a significant increase in death rates across the western US. The study, led by Phillip J. van Mantgem and Nathan L. Stephenson, analyzed long-term data from over 6,000 trees and found that regional warming is a key factor contributing to this trend.
A new study reveals that spitting cobras create complex geometric patterns of venom when striking, which are actively produced by the snake's muscles. This allows them to hit their targets with remarkable precision, making contact with an attacker's eyes where it causes severe pain and possibly blindness.
A study by Ralph Brinster found that males housed with females had a six-month delay in fertility decline, compared to those without companionship. This could have significant implications for male fertility in wildlife and human populations.
A study by University of Iowa researchers has documented MRSA in swine and swine workers in the US for the first time. The investigation found a high prevalence rate of MRSA among swine and swine handlers, suggesting transmission between animals and humans.
Researchers at UCSF have identified a woman's immune system anomaly that may lead to breakthrough therapies for autoimmune diseases like rheumatoid arthritis and colitis. The discovery of antibodies blocking T-cell movement could result in more targeted treatments with lower risks of infections or tumors.
Researchers developed a quality-of-life survey for children, allowing doctors to understand the results in the same way they understand blood pressure test results. The survey includes questions about children's daily lives, helping pediatricians identify potential health problems.
Researchers at the University of Bristol have demonstrated an optical device that filters two photons based on their polarisation correlations, a key characteristic of quantum entanglement. This 'entanglement filter' has significant implications for quantum technologies, including computers, communication, and advanced measurement.
A patented Michigan State University process pretreats corn-crop waste to enhance its usefulness and reduce costs. The AFEX (ammonia fiber expansion) method breaks down cellulose and hemicellulose in plants more efficiently, allowing for the creation of biofuels from cellulose without added nutrients.
A University of Pittsburgh study analyzed reactions to the 2001 US Postal Service anthrax attacks, finding that confusion, distrust, and conflicting information from media organizations shaped postal worker responses. The study highlights the importance of trust-building and education to facilitate clear communication during bioterrori...