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Science News for January 6, 2009


Angina: New drug gets right to the heart of the problem

Researchers discover novel compound F15845 that targets persistent sodium current, causing permanent excess sodium influx in heart cells. The drug has shown promising results in animal studies, with acceptable bioavailability when given orally.

SourceWiley·JournalBritish Journal of Pharmacology·DateJan 6, 2009

Physical activity may not be key to obesity epidemic

Researchers from Loyola University Health System found no significant difference between African American women in metropolitan Chicago and Nigerian women in terms of calories burned during physical activity. The study suggests that dietary intake may be more important than energy expenditure level in the rising rates of obesity.

SourceLoyola Medicine·JournalObesity·DateJan 6, 2009

On a high-fat diet, protective gene variant becomes bad actor

A gene variant that protects against weight gain and insulin resistance becomes a bad actor on high-fat diets, new research suggests. Mice with the Ala12 variant show improved insulin sensitivity and better plasma lipid profiles on balanced diets but worsen these outcomes when fed a diet high in fat.

SourceCell Press·JournalCell Metabolism·DateJan 6, 2009

Big, old mice spread hantavirus

A recent study by University of Utah researchers identified bigger, older mice as the culprits behind hantavirus transmission. The study used fluorescent powders and radio transmitters to track contacts between mice, revealing that larger-bodied individuals were responsible for maintaining the disease in deer mouse populations.

Wii Fit a promising tool for all ages

According to Kansas State University researcher David Dzewaltowski, Wii Fit can be an effective tool to promote physical activity and create or maintain a healthy lifestyle. However, the game's health measurements, such as BMI calculation and fitness age measurement, have flaws and are not suitable for children.

SourceKansas State University·JournalExercise and Sport Sciences Reviews·DateJan 6, 2009

Traditional risk assessment tools do not accurately predict coronary heart disease

A recent study published in the American Journal of Roentgenology found that traditional risk assessment tools do not accurately predict coronary heart disease. The study analyzed 1,653 patients and found that 21% of those thought to need statin drugs did not require them, and 26% of those already taking statins had no detectable plaque.

SourceAmerican College of Radiology·JournalAmerican Journal of Roentgenology·DateJan 6, 2009

Nicotine gum effective for gradual smoking reduction and cessation

A new study published in the American Journal of Preventive Medicine found that nicotine gum can aid in gradual smoking reduction and cessation. The study showed a significant increase in odds of quitting (40-90%) and overall success rates (2-6 times) for participants using active nicotine gum, making it an effective treatment option f...

SourceElsevier Health Sciences·JournalAmerican Journal of Preventive Medicine·DateJan 6, 2009

Wonderful cheese is all in the culture

Researchers at Newcastle University have identified a new line of bacteria responsible for the ripening process and flavor of French cheese Reblochon. The reblochoni microbes, part of the Actinomycetes group, outcompete traditional starter cultures to provide flavor.

SourceNewcastle University·JournalINTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY·DateJan 6, 2009

Four, three, two, one . . . pterosaurs have lift off

Ancient flying reptiles employed all four limbs for take-off, defying conventional wisdom. The study reveals that pterosaurs had stronger front limbs than legs, allowing them to generate massive power without sacrificing size. This discovery sheds new light on the biology and evolution of these fascinating creatures.

SourceJohns Hopkins Medicine·JournalZitteliana·DateJan 6, 2009