A new study found that childless women are diagnosed with chronic arthritides an average of 5.2 years before parous women. The study, which analyzed data from over 500 women, also found that nulliparous women have a higher educational level and may possess a lower disposition to developing arthritis.
Researchers develop synthetic protein that induces blood clotting, cutting off tumor's nutrient and oxygen supply. The treatment resulted in a 53% decrease in tumor volume and slowed cancer cell growth by 49%.
A study published in the World Journal of Gastroenterology found that type 2 diabetes mellitus is an independent risk factor for hepatocellular carcinoma. The research revealed a direct association between HCC and insulin/sulphanylureas treatment, as well as an inverse relationship with metformin therapy.
Researchers at Oklahoma State University will develop a miniature optical dating instrument (ODIN) for dating the surface of Mars. The ODIN utilizes optically stimulated luminescence (OSL), a geological dating technique, and aims to further our understanding of Martian climate and atmosphere conditions.
A new study connects abnormalities of cortisol with symptoms of depression in obese children, indicating a hormonal link between the two conditions. Cortisol levels in the afternoon and evening correlate positively with depressive symptoms, suggesting that obesity and depression may have a shared underlying cause.
Researchers studied DNA from 1,930 pneumococcus strains and found a link between bacterial recombination and antibiotic resistance. Bacteria that undergo sex with other species are more likely to develop resistance to antibiotics, making treatment increasingly difficult.
A new study found that bariatric surgery nearly doubles the expected risk of fractures, especially hand and foot fractures, in patients who underwent weight loss surgery to treat medically complicated obesity. The researchers analyzed data from 97 patients with an average age of 44 years and found a total of 31 fractures after surgery.
Research found that obese children as young as 7 years old have abnormal blood markers predicting cardiovascular disease. Simple obesity can raise risk before the metabolic syndrome develops.
Researchers found that nicotine promotes insulin resistance, raising blood sugar levels higher than normal. This condition increases the risk of cardiovascular disease in smokers.
Conventional body fat measurements overestimate obesity in African-Americans compared to Caucasians of the same age and weight. The study suggests that muscle mass may be higher in Blacks, which could explain the discrepancy.
Scientists discovered 'snow roots' in Corydalis conorhiza plants, which extend through layers of snow to take up nitrogen. This unique adaptation allows the plant to feed on nutrients before the growing season begins.
Noroviruses cause the greatest incidence of vomiting and diarrhoea globally, resulting in approximately 200,000 child deaths annually. A new study suggests that targeting sugar chains with sialic acid could prevent virus attachment to cells.
Researchers have successfully engineered a tunable bandgap in bilayer graphene, opening the way for nanoscale electronics and photonics. The breakthrough allows for precise control over the bandgap size and doping level, enabling new types of nanotransistors and nano-LEDs.
The revised Vienna Classification enhances diagnosing colorectal polyps and lesions with improved sensitivity and specificity. However, it has limitations in predicting depth of invasion, and should be supplemented by endoscopic assessment.
Researchers at Johns Hopkins School of Medicine have discovered that the AMPA receptor protein moves to its destination with the help of the 4.1N protein, forming long-term memories. The study found that 4.1N is required to maintain strong connections between neurons, making memories stick.
A large cohort study found that metoclopramide poses no significant risks for fetal development when used to relieve morning sickness nausea, supporting its safe use during pregnancy. The study analyzed data from over 80,000 infants born to mothers who received the medication during the first trimester.
A new study found that hormone therapy combined with physical activity significantly reduces belly fat and body fat percentage in postmenopausal women. The research, which included 34 healthy women, showed that active women had lower waist measurements and better cholesterol levels after 4 months of hormone replacement therapy.
A study of 159,856 individuals found that socioeconomic status, gender, and marital status are significant predictors of sleep disturbances. Women reported more sleep problems than men, while married individuals slept better than single individuals.
A new clinical trial has begun at Massachusetts General Hospital to expand restorative neurotechnology research for patients with paralysis. The trial aims to harness brain signals to control assistive devices, such as computers and prosthetic limbs, for people with spinal cord injuries, ALS, or limb loss.
Dogs can be diagnosed with osteoarthritis early on through synovial fluid analysis, which could help prevent the disease or reduce its progression. Researchers found altered synovial fluid quantity and quality in injured joints, suggesting potential biomarkers for early detection.
Astronomers use new calculations to redefine habitable zones, considering tidal forces that can impact planet's climate and life. The revised definition limits potential habitable environments, focusing searches on overlapping zones.
The Chinese Journal of Natural Medicines is now available in English on ScienceDirect, increasing international accessibility to Chinese medical research. This expansion enables pharmaceutical and medical scientists to stay updated on the latest advancements in traditional Chinese medicines.
A team of scientists at The University of Texas M. D. Anderson Cancer Center has identified four new targets for breast cancer treatment, including three lysophosphatidic acid receptors and the enzyme autotaxin. These targets are found to be abnormally expressed in many types of cancer and have been shown to cause cancer.
The BrainGate2 pilot clinical trial is taking place at Massachusetts General Hospital, extending prior safety and feasibility research of the BrainGate Neural Interface System. The trial aims to help patients with spinal cord injury, stroke, muscular dystrophy, ALS, or limb loss turn their thoughts into actions.
Research finds that new mothers experience exhaustion due to disrupted nighttime sleep, rather than inadequate sleep duration or timing. Postpartum women's sleep-wake cycles remain aligned with their preferred schedule.
Astronomers at the Science and Technology Facilities Council's William Herschel Telescope have confirmed an effective way to search the atmospheres of planets for signs of life. This method uses transmission spectra, which can reveal vital information about a planet's atmosphere, providing clues about potential biological processes.
Researchers found that BPA exposure during pregnancy leads to a permanent change in the DNA of offspring, affecting uterine development and fertility. The study's findings suggest that pregnant women should avoid BPA exposure to minimize potential harm to their unborn children.
Researchers found pre-pregnancy depressive mood may be a risk factor for premature birth among both blacks and whites, but the study did not establish cause and effect. Black women have nearly twice the odds of having a preterm birth compared to white women, potentially due to declining health over time.
Research finds that poor sleep affects relationship satisfaction, with negative partner interactions leading to worse sleep the next night. Couples' quality of sleep also impacts their subsequent relationship functioning.
Researchers have developed a new white paper coating inspired by the Cyphochilus beetle's shell, which produces a bright and efficient whiteness. The coating uses a unique structure to scatter white light, resulting in a lighter weight paper with high whiteness, potentially reducing costs.
Dr. Michael J. Wade, a renowned evolutionary biologist, will receive the 2009 Sewell Wright Award for his seminal contributions to multi-level selection and the study of evolution. His work has been cited over 5500 times and has formed a significant part of the conceptual landscape for the 'levels of selection' discussion.
Researchers found that typhoons trigger slow earthquakes in eastern Taiwan, with 11 events occurring within a five-year study period. The slow quakes are characterized by non-violent fault slippage events that release energy hours or days after the typhoon passes.
A study found that hospitalists who staff short-stay units with accessible diagnostic tests and consultations have successful stays. Patients requiring less complex care had successful stays, while those needing specialty consultations were more likely to have unsuccessful stays.
Research found that adolescents who get more high-quality sleep have better math scores, while those who experience difficulties waking up tend to perform worse in English. The study suggests that a consistent sleep schedule is crucial for academic success, especially during critical developmental periods.
Research by Emory University scientists identifies a mechanism in mother mice's brains that focuses their awareness on the calls of baby mice. The high-frequency sounds of pups inhibit neurons more attuned to lower frequency sounds, enhancing contrast and making them stand out.
Researchers discovered that mother mice exhibit increased call-evoked inhibition in response to pup isolation calls, allowing for more effective detection in noisy environments. This neural plasticity improves the contrast between high-ultrasonic and lower-frequency neural populations.
Versartis has presented positive preclinical data on its two product candidates, VRS-317 and VRS-826, which have the potential to extend half-life of drugs. The company's compounds have shown in vivo potency equal to daily hGH and sustained plasma levels without toxicity.
Researchers have gained new understanding of the disease through a groundbreaking animal model, revealing that B cells play a critical role in its development. The study also highlights the importance of aggressive T cells, which attack brain tissue and trigger antibody attacks by B cells.
Researchers have found that humans are likely exposed to a daily dose of bisphenol A (BPA) that far exceeds the current estimated safe daily intake dose. The study, which involved five female adult monkeys, suggests that BPA exposure comes from multiple unknown sources beyond food and beverage containers.
A randomized trial of 500 women with twin pregnancy found that progesterone treatment did not reduce the likelihood of delivery or intrauterine death before 34 weeks. The meta-analysis also confirmed that progesterone does not prevent early preterm birth in twin pregnancies.
Tulane University is partnering with South American universities to address the high burden of cardiovascular disease in the region, which claims one-third of chronic disease deaths. The new center will focus on research, training, and health education to prevent and treat CVD through quantitative methods and skills development.
Recent research found that Tribble 3 can block the insulin signaling pathway, contributing to insulin resistance and NAFLD. The study provides an experimental basis for future studies on the role of TRB3 in NAFLD.
The National Heart, Lung, and Blood Institute (NHLBI) is funding a network of research and training centers in developing countries to prevent and control chronic diseases. The centers will conduct research tailored to local needs and foster the training of emerging scientists and health professionals. With UnitedHealth Group's Chronic...
A recent study published at the SLEEP 2009 conference found that caffeine use prevented increased risky behavior in individuals subjected to extreme sleep deprivation. Despite prolonged sleep deprivation, participants who consumed caffeine showed no significant increase in impulsive risk-taking behavior, unlike those receiving a placebo.
A recent study found that individuals with rheumatoid arthritis experience significant disturbances in their body clock, leading to worsening of symptoms. The research identified a specific genetic pathway responsible for interactions between the genes regulating the body clock and those exacerbating arthritis symptoms.
A study published in Nature found that fat cells in bone marrow suppress blood production, making it harder for patients to recover from chemotherapy or radiation. Blocking this fatty infiltration could enhance blood recovery after transplant.
Researchers at the University of Montreal Hospital Research Centre have developed a new surgical technique to treat refractory epilepsy, with nine patients showing successful results. The innovative approach reduces risks and complications associated with previous insular surgeries.
A study by Baylor College of Medicine found that retinoic acid and Neurogenin2 cooperate to activate chromatin and determine nerve progenitor cells become motor neurons. This discovery may lead to generating motor neurons from different stem cells and developing tools for drug screening.
A new study evaluates expected ground motion in Seattle, Victoria, and Vancouver from earthquakes of magnitude 7.5 - 9.0, providing a tool to build or retrofit structures to withstand seismic waves. Ground motions are estimated for firm ground at the three sites, with a model that engineers can adjust for local soil conditions.
A study of 133 women with rheumatoid arthritis found that symptoms such as pain and depression significantly impacted sleep quality. Treating depression may also improve pain and medication adherence, according to researchers.
Researchers uncover neural mechanism supporting adaptability and decision-making under uncertainty, with the frontal lobe playing a critical role in tracking evidence and switching behavior.
A recent study published at SLEEP 2009 found a significant link between poor sleep quality and an increased risk of death. The research, which followed over 5,600 participants for eight years, revealed that two specific types of sleep-stage transitions were associated with higher mortality risk.
The report reveals stark contrasts in tobacco control policies and use across the US, with serious disparities remaining. States with strong programs and policies exhibit lower smoking prevalence and higher quit rates, while others lag behind, hindering overall progress.
Engineers from Penn and Sandia National Laboratories demonstrate the formation of interconnected carbon nanostructures on graphene substrate using a simple assembly process. The discovery may lead to new approach of graphene-based electronic devices.
A new study found that postpartum anxiety can delay puberty in both biological and adoptive daughters of affected mothers, regardless of maternal behavior or environment.
A new study suggests that natural hormone angiotensin 1-7 may help treat the metabolic syndrome, a cluster of risk factors increasing heart disease and diabetes risk. Angiotensin 1-7 lowered fasting insulin levels and improved triglycerides and blood sugar in fructose-fed rats.
Researchers discovered a protein profile that may accurately predict tamoxifen resistance in breast cancer patients. The study found that the extracellular matrix metalloproteinase inducer (EMMPRIN) was significantly associated with an earlier tumor progression and poor clinical outcome.
Researchers found that two-channel GES with trains of pulses can entrain gastric slow waves and accelerate gastric emptying. This treatment approach may be applicable for treating gastroparesis and normalizing gastric dysrhythmia.
A zero-tolerance policy towards underage alcohol use in the home may significantly reduce the likelihood of college students binge drinking, according to a study by Caitlin Abar. The study found that students whose parents did not permit them to drink underage were less likely to engage in heavy drinking, regardless of gender.
Exposure to low-dose BPA and estrogen increases arrhythmias in female rats and mice, a new study found. The results suggest a possible risk for female heart health due to increased levels of estrogens in the body and exposure to environmental estrogen BPA.