Researchers found women tend to be younger when developing lung cancer, despite smoking less than men, increasing the risk of tobacco carcinogens. Women's awareness of other cancers like breast cancer may also contribute to their vulnerability, with median survival after surgery being longer for women.
Researchers created short lengths of molecules that resemble ribonucleic acid to bind to CAG repeats, preventing cells from creating abnormal proteins. These compounds were effective against Huntington's and Machado-Joseph diseases, but further tweaking is needed to minimize effects on normal proteins.
A recent genetic study has confirmed the immune system's role in narcolepsy, revealing that autoimmunity plays a crucial part in the disorder. The study found unique variants of genes HLA-DQB1*0602 and TCRA associated with narcolepsy-cataplexy.
Researchers discuss personalized treatment options for early-stage lung cancer, using targeted therapies and cancer vaccines. A gene signature is being used to predict which patients will benefit from an immune-boosting vaccine designed to target MAGE-A3 protein.
Researchers at VIB develop efficient and safe gene delivery approach based on non-viral genetic elements called transposons, overcoming limitations of viral vectors. This technology may simplify gene therapy, improve safety and reduce costs, treating cancer and genetic disorders.
Biologists at CCNY and CSHL found that zebra finches isolated as juveniles produce songs similar to those sung by the species in the wild after multiple generations. The findings suggest that culture is encoded in birds, with traits emerging through evolutionary processes.
Identifying a transcription factor that regulates blood stem cells, researchers found ELF4 activates an inhibitor that stops naive T cells from proliferating. This discovery could lead to better vaccines and more effective cancer immunotherapy by controlling T cell growth and production.
Research highlights the importance of fathers' mental health on child development, citing increased risks for behavioral and emotional problems, anxiety disorders, and substance abuse. The study also notes the potential for 'child-to-parent effects' and emphasizes the need for further international research.
The March of Dimes has awarded a $250,000 prize to Kevin P. Campbell and Louis M. Kunkel for their pioneering work identifying the genes and proteins that cause muscular dystrophy. Their research has led to better diagnostic tools and potential treatments, improving the lives of over 250,000 Americans affected by the disorder.
Researchers at Yale University have developed a novel approach to deliver small interfering RNA (siRNA) molecules using biodegradable nanoparticles, achieving sustained release and effective knockdown of gene activity. This breakthrough holds promise for the treatment of sexually transmitted diseases (STDs), particularly HPV and HIV.
A study by CSHL and CCNY found that zebra finches raised in isolation develop a song culture after introducing improvisations from their tutors, eventually resembling wild-type songs. The results provide insights into the evolutionary process of language.
Researchers at Case Western Reserve University have discovered a form of synaptic memory in the olfactory bulb, which could explain how we store information about specific smells. This finding provides a new perspective on the brain's processing of sensory information and has implications for understanding human memory.
Researchers confirm that narcolepsy is an autoimmune disease caused by a specific immune cell variation. A study found that nearly 90% of patients with narcolepsy carry a variant of the human leukocyte antigen gene, which is also associated with other autoimmune diseases like multiple sclerosis and juvenile diabetes.
A new study finds that women who have babies in their 40s or 50s tend to live longer than other women, and their brothers also live longer, but not their wives. The study suggests that genes may play a significant role in prolonging lifespan and female fertility.