NC State researchers investigate how engineered nanomaterials interact with biological systems, focusing on fullerenes' size and surface charge effects. The study aims to understand nanoparticles' absorption, distribution, metabolism, and excretion (ADME) in the body.
Stereotactic radiosurgery is an effective and safe method for eliminating tremors caused by Parkinson's disease and essential tremor. Long-term results show that SRS favorsably compares to deep brain stimulation and radiofrequency treatments in terms of tremor relief and complications.
A new study found that golfers with obstructive sleep apnea who received nasal positive airway pressure (NPAP) treatment improved their daytime sleepiness scores and lowered their golf handicap by as much as three strokes. The study suggests that the possibility of improving one's golf game may be a significant motivator to improve NPA...
Researchers found proton therapy to have excellent early tolerance with minimal urinary and rectal toxicity. The study showed a low rate of Grade 3 genitourinary and gastrointestinal side effects, with the most common being minor rectal bleeding.
Researchers have identified a molecular mechanism underlying DES-induced male infertility in mice, which may be linked to increased incidence of human reproductive disorders. The study found that neonatal exposure to DES disrupts the protein NR0B2, leading to reduced fertility and protected males against negative effects.
Researchers discovered that neutrophils, a type of white blood cell, lose their direction when the protein p55 is absent. This leads to impaired healing and slower response times to infections.
A new study published in Nutrition Journal indicates that XanGo Juice has lowered levels of C-reactive protein (CRP) in overweight and obese people, suggesting potential benefits for heart health and diabetes. The juice also showed significant reductions in body fat percentage and BMI scores.
Researchers at the University of California, Santa Cruz, used stable-isotope analysis to investigate the number of human victims killed by the famous lions. The study found that one lion likely ate 11 humans and the other consumed 24 people during their final nine months.
Researchers found that nearly 98% of patients with early-stage non-small cell lung cancer who are unable to undergo surgery experienced no growth of the disease after three years. Additionally, over half of these patients lived for three years after diagnosis, while fewer than 20% experienced a serious decline in health status.
China has seen improvements in forest growth and marine ecosystem health, but severe pollution and biodiversity loss still threaten the country's environment. Despite major government efforts, China faces significant challenges in protecting its rich biodiversity.
New data from a 10,000-kilometer cruise reveals that iron availability significantly controls the input of fixed nitrogen into the Atlantic Ocean. This finding is crucial for understanding global climate patterns and their potential implications on carbon dioxide sequestration.
A clinical trial has shown that healthy pregnant women mount a robust immune response after receiving just one dose of the 2009 H1N1 influenza vaccine. The vaccine has been well-tolerated and elicits protective immune responses in a significant majority of participants.
The majority of malaria endemic countries adopted effective artemisinin combination therapy more than three years ago, but its availability remains low in public and private sectors. Ineffective monotherapies dominate the market share in many countries, with some products costing up to 65 times the minimum daily wage.
A clinical trial has begun testing a novel compound, STX107, that selectively targets the synaptic defect underlying Fragile X syndrome. The study aims to evaluate safety and tolerability in healthy volunteers, with potential progression to phase 2 trials in adults and pediatric safety assessments.
Researchers found widespread poor compliance with regular cleaning of public restrooms on cruise ships may predict subsequent norovirus infection outbreaks. The study evaluated the thoroughness of disinfection cleaning and found that toilet seats were best-cleaned objects while baby changing tables were least cleaned.
A study found that adding proton therapy 'boost' to X-ray radiation therapy significantly reduces prostate cancer recurrences in low- and intermediate-risk patients. The high-dose treatment also proves safe with minimal side effects, benefiting these patients with conventional doses of radiation.
A study by NOAA researchers found that about half of 36 fish stocks in the Northwest Atlantic Ocean have shifted northward over the last four decades, with some nearly disappearing from U.S. waters as they move farther offshore. Fish species are adapting to changing temperatures by moving to cooler or deeper waters.
A team of researchers from Pitt and Walter Reed Army Institute of Research have identified compounds that hold promise for treating leishmaniasis, a parasitic infection affecting millions worldwide. The newly developed strategy, called HILCES, uses high-throughput screening to identify effective drug candidates.
Researchers found that individuals with both childhood adversity and traumatic events in adulthood are more likely to develop PTSD. The study also revealed that a genetic mutation can interact with these factors to increase the risk of developing the condition.
Researchers at University Hospitals Case Medical Center report promising results from a study treating glioblastoma multiforme with Gamma Knife radiosurgery, increasing patient survival rates by almost four months compared to traditional radiotherapy alone.
A Rice University lab has discovered over 2.7 million possible structures for molecular sieves, also known as zeolites, which have potential applications in industries such as gasoline production and laundry detergents.
A large study found that early-stage HER2-positive breast cancer patients with tumors one centimeter or smaller are at a significant risk of recurrence. This shift in assessment may lead to the consideration of additional therapy, such as Herceptin-based treatment.
Long-standing theoretical predictions have been confirmed in tokamaks, leading to improved performance and efficiency. High-pressure plasmas exhibit synergistic effects, minimizing turbulence and maximizing self-generated heat, which can sustain hot and dense plasma for longer periods.
The study reveals a significant ice loss on Mount Kilimanjaro, primarily attributed to rising global temperatures. The ice volume has decreased by roughly equal proportions through thinning and shrinking, with 85% of the ice lost since 1912.
Researchers developed an immune system cell therapy that targets Epstein-Barr virus, providing long-term protection to patients with severely compromised immune systems. The therapy, effective for up to nine years, was found to prevent lymphomas associated with EBV infection in over 100 patients.
Pseudomonas aeruginosa produces rhamnolipids to form a biofilm shield that kills white blood cells, evading the immune system and antibiotic treatment. This 'launch a shield' response could lead to novel antimicrobials for treating antibiotic-resistant infections.
Researchers have developed a tiny, gold nanocage that responds to light and releases carefully titrated amounts of chemotherapy drugs at specific tissue sites. The system is designed to maximize the beneficial effects of the medication while minimizing side effects.
Researchers at Georgia Tech have developed a new type of three-dimensional photovoltaic system using zinc oxide nanostructures grown on optical fibers. The approach allows PV systems to be hidden from view, providing an alternative to traditional rooftop installations.
The world's top experts in endangered languages are converging at the University of Utah to create a comprehensive online database. The gathering aims to preserve 7,000 languages that are at risk of extinction, with nearly 90% predicted to disappear in the next 100 years.
The cucumber genome has been sequenced, offering a platform for studying the cucurbit family and plant biology. The genome will aid in understanding disease and pest-resistance, flavor traits, and sex expression, with potential applications in agriculture.
Researchers at Duke University have developed a simple and inexpensive method for loading cancer drugs into nano-scale delivery vehicles. The new formulation showed promising results in animal models, eliminating tumors after a single treatment while reducing side effects associated with systematic chemotherapy.
A study found that sleep deprivation causes individuals to shift from automatic to controlled processes of information categorization, leading to performance deficits. The study involved 49 West Point Cadets who performed an information-integration categorization task twice with or without sleep between sessions.
A recent space experiment using the Fermi Gamma Ray Space Telescope has provided evidence about the fundamental structure of space and time. The team confirmed aspects of Einstein's theories of gravity, which unite space and time in the concept of space-time.
The Global Action Plan for the Prevention and Control of Pneumonia outlines a six-year plan to control the disease, with a focus on promoting exclusive breastfeeding, vaccinations, and effective case management. Implementing these interventions could save more than one million lives each year.
Research finds that lung cancer patients treated in public hospitals are more likely to have advanced stage cancer than those in private hospitals. The study highlights the need for an organized and timely approach to diagnosis and treatment to reduce health care disparities.
A study confirmed the efficacy of a simple questionnaire in identifying patients at high risk for lung cancer. The questionnaire, completed by over 1,000 patients, found almost half qualified as high risk and led to eight confirmed cases of lung cancer in five years.
A study shows that retirement is followed by a sharp decrease in sleep disturbances due to reduced work-related demands and stress. Sleep disturbance prevalence rates fell from 24.2% to 17.8% after retirement, with the greatest reduction reported among participants with depression or mental fatigue.
Research into breast cancer development, chronic pain and inflammatory diseases receives ARC funding to investigate epigenetic modifiers, immune responses and protein interactions. The institute aims to develop basic discoveries into clinical benefits for patients worldwide.