A recent study by MUHC/McGill researchers suggests that tuberculosis treatment guidelines should be revised, recommending extended treatment periods for new cases and more effective combinations of drugs to avoid drug resistance. The World Health Organization is urged to review its directives to benefit the global community
Researchers found that athletes with previous injuries to the anterior cruciate ligament (ACL) tend to have smaller ACLs than those without injuries. The study suggests that a smaller ACL may be more susceptible to injury due to various factors such as activity level, neuromuscular coordination, and muscle strength.
Researchers found a diabetes drug, metformin, selectively targets and kills cancer stem cells in mice, reducing tumor growth and prolonging remission. The compound's effectiveness is attributed to its ability to work independently of insulin sensitivity improvements.
A CU-Boulder study found that 30% of showerheads harbor significant levels of Mycobacterium avium, a pathogen linked to pulmonary disease. The researchers discovered biofilms on the inside of showerheads containing high loads of M. avium and related pathogens.
A meta-analysis of previously published research found that implantable cardioverter-defibrillator therapy does not significantly reduce all-cause mortality in women with advanced heart failure. This suggests that a larger study population may be needed to show any benefit of defibrillator implantation in women.
Researchers are studying the principles of perception in art using both artistic and neuroscientific viewpoints. The collaboration aims to understand how we gaze at art pieces compared to non-artistic images.
Dean Franklin, an engineer, and two physicians, Robert Rushmer and Robert Van Citters, pioneered noninvasive imaging and treatment of the heart. They developed devices that measured blood flow, heartbeat dimensions, and blood pressure without cutting open the body.
A study by psychologists found that individuals with strong moral convictions tend to distrust authorities' decisions, while those with high religiosity trust them. Participants based their trust on gut reactions rather than thoughtful deliberation.
A study published in Aging Cell found that the conserved protein d4eBP protects heart function against aging, revealing a potential mechanism for cardiac aging. The research also sheds light on the TOR and FoxO signaling pathways, with implications for human heart health.
Researchers at University of Michigan have developed a nanoemulsion lotion that sharples curbs bacterial growth and reduces inflammation in second-degree burns. The treatment shows promise in overcoming current creams' limitations, reducing bacterial growth one-thousand-fold compared to control animals.
A web-based screening tool identified unhealthy alcohol use among university students, who received personalized interventions to reduce drinking. After one month, participants showed significant decreases in drinking frequency and volume.
John Leslie, K-State's plant pathology head, received the Fellowship honor from the American Phytopathological Society. He will also join Seoul National University as an adjunct professor, continuing collaborative research and educational opportunities.
Children with microcephaly are at risk of neurologic and cognitive problems, including epilepsy, cerebral palsy, mental retardation, and eye and ear disorders. Doctors recommend screening for coexisting conditions, brain scans, and genetic testing to identify the causes of microcephaly.
A recent meta-analysis published in Cancer found that depression is associated with a higher risk of death in cancer patients, with death rates up to 25% higher for those experiencing depressive symptoms. The study highlights the need for systematic screening and treatment of psychological distress in cancer patients.
Researchers at Harvard Medical School have discovered a diabetes drug that selectively targets and kills cancer stem cells in mice, leading to faster tumor reduction and prolonged remission. The findings support the potential use of metformin as a first-line treatment in breast cancer patients.
The 2009 Lasker Awards honor pioneering work in cancer and stem cell research, promising new therapies and a $700 million global market. Renowned scientists receive awards for their discoveries in nuclear reprogramming techniques and regenerative medicine.
A new study published in CMAJ found that 1 in 20 patients experience critical events such as death or major resuscitation during urgent air-medical transport. Factors associated with these events include female sex, traumatic injuries, and cardiovascular disease.
Researchers studied polyploidy's effects on cell division in plants, finding that some cells can tolerate aneuploidy without detrimental consequences. The study provides new insights into how genetic changes can lead to evolutionary change and affect plant fitness.
Blood vessels can spur their own growth and deliver oxygen to tissues and tumors through internal cues. The study found that a protein called Flt-1 plays a key role in regulating this process.
A study by American Cancer Society found that many breast cancer patients are not receiving targeted therapies due to lack of testing. Inaccurate HER2 test results also affect treatment choices, highlighting the need for better testing practices.
Researchers found that green tea component EGCG can prolong the preservation of stored blood platelets by up to six days via anti-apoptosis properties. Additionally, EGCG was shown to preserve skin tissues by controlling cell division and preventing oxidation, allowing for the storage of skin grafts up to seven weeks.
Researchers found that idiomatic sentences activated the right middle temporal gyrus and right medial frontal gyrus, indicating a more complex understanding process. The left hemisphere's role in suppressing literal meaning was not specifically activated, but limbic regions involved emotional responses were.
A UH Mānoa team led by Ralf Kaiser discovered triacetylene formation in Titan's atmosphere through simulation experiments and theoretical calculations. This finding sheds light on the origin and chemical evolution of Saturn's moon, which may serve as a building block for more complex polyynes.
The Bcl-xL protein prevents bone breakdown by negatively regulating the bone-resorbing activity of osteoclasts. In mice, Bcl-xL promotes osteoclast survival and decreases extracellular matrix production, leading to increased osteoclast-mediated bone resorption.
A study found increased risks of breast cancer in women from the most exposed zone and an excess of lymphatic and hematopoietic tissue neoplasms in all but the least exposed zone. Researchers analyzed medical records of over 36,000 individuals exposed to dioxin after a 1976 industrial accident.
T cells from XLP patients are resistant to cell death triggered by repeated stimulation of the TCR complex. This resistance enables uncontrolled T cell expansion upon infection with common viruses like infectious mononucleosis.
A recent study published in Archives of Internal Medicine found that 29% of chronic angina patients experience angina chest pain at least once a week. Despite treatment options, many patients report limited enjoyment of life due to the symptom.
A new once-daily medication has shown to be as effective as multiple dosings for treating the most common mouth infection in HIV/AIDS patients. The treatment, a small tablet applied daily, provides relief from oral candidiasis (OC) with few or no side effects.
A new study found that occupational pesticide exposure is associated with an increased risk of developing Parkinson's disease. The study, published in Archives of Neurology, investigated the link between pesticide use and parkinsonism, and found that certain pesticides more than doubled the risk of the disease.
Loyola will raise an additional $2 million from private donors to match The Coleman Foundation's $2 million grant. The new bone marrow transplant wing will be named The Coleman Foundation Bone Marrow Transplant Center.
Researchers found that wntP-1 gene expression occurs at all wound sites, triggering regeneration polarity in planaria. Blocking the gene results in heads regrowing instead of tails.
Researchers validated a simple blood test to assess treatment effectiveness in metastatic breast cancer patients, correlating CTC count with disease response. The study supports the use of CTC enumeration as an adjunct to standard clinical and radiographic methods.
Stevens will deliver workshops and training to assist the LWD in maintaining workforce vitality and flexibility. The grant aims to improve efficiency and quality through Lean manufacturing applications and bioinformatics.
Researchers will study turbulent transport and organization in fusion and astrophysical plasmas to design better, smaller and cheaper fusion systems. Understanding the link between flow self-organization and large-scale flow dissipation may also improve ITER's fusion power production.
Tropical Storm Koppu is expected to make landfall in mainland China on September 15, bringing heavy rainfall, heavy surf conditions, and gusty winds. The storm has sustained winds near 69 mph and is forecast to strengthen slightly before landfall.
Researchers found that carnivorous plant traps are cheaper to make than leaves, contrary to evolutionary predictions. This discovery sheds light on how complete food webs operate, highlighting the benefits and trade-offs of nutrient allocation in plant ecology.
A study found laser therapy equivalent to corticosteroid medications in treating vision loss from BRVO, with lower complication rates. Laser treatment showed no significant difference in visual improvement compared to corticosteroid injections.
Researchers found that a disruption in the spectrin-actin network leads to irregularities in lens cell packing and shape. The study suggests that mechanical stresses during lens growth and eye movements cause this disorganization.
Researchers are designing liver mimics that can eventually form the basis for extracorporeal liver-assist devices. The primary research goal is to assemble 3D cellular structures that mimic the liver, capturing precise spacing between different cell types.
New research suggests that some nonhuman animals, including dolphins and macaque monkeys, may possess functional parallels to humans' consciousness and cognitive self-awareness. These species exhibit behaviors such as hesitation and uncertainty, indicating a capacity for metacognition.
A melon-derived antioxidant supplement has been shown to relieve stress and fatigue in healthy volunteers. The study found significant improvements in perceived stress symptoms after 28 days, but not beyond the initial 7-day period of placebo effect.
The introduction of new prenatal tests for Down syndrome has led to a steady decrease in births of babies with the condition since their introduction. Experts argue that existing tests may not be providing accurate information, leading to difficult conversations between physicians and expectant parents. To address this, researchers are...
Research shows prolonged stress can induce cell death in aging-related diseases like atherosclerosis and neurodegeneration by triggering the endoplasmic reticulum (ER) to release calcium stores. ER proteins ERO1-alpha and IP3R play a crucial role in this process, suggesting potential new targets for treatment.
Researchers have discovered that applying capsaicin to specific skin locations can trigger signals in the nervous system, activating cellular pathways that protect the heart. This technique has shown promise in reducing cardiac cell death by up to 85%.
Research reveals that parasitic worm infections are prevalent in Northern Rwanda, with those infected more likely to be underweight. The study also found a link between parasite infections and anemia, but not significant growth stunting.
A new UT Southwestern study suggests that fat from certain foods makes its way to the brain, causing it to send messages to cells warning them to ignore hunger signals. The researchers found that palmitic acid, a type of saturated fatty acid, is particularly effective at triggering this mechanism.
Researchers will drill through Lake Vida's thick ice cap to study the brine and sediment below, aiming to understand the ecosystem's history and its survival strategies in extremely cold conditions. The project, funded by a $1.1 million grant, may reveal insights into life on Earth dating back thousands of years.
A new corticosteroid medication has been shown to improve vision and reduce vision loss in patients with central retinal vein occlusion. The treatment, which involves eye injections of the medication, has been proven effective in reducing vision loss by five times.
Researchers found BRAF mutations in all nevus cells but wild-type BRAF predominated in nine of 13 cases. Heterozygous patients showed simultaneous amplification of BRAF and a neighboring polymorphism, suggesting alternative melanocyte transformation mechanisms.
NASA's Aqua satellite captured infrared and visible images of Fred's clouds stretching from northeast to southwest after declaring the storm 'dead' on September 12. The remnants of Fred are expected to produce intermittent shower and thunderstorm activity as it moves west-northwestward over the next couple of days.
A new study by Management Insights suggests that Iraq veterans may be experiencing a PTSD rate of up to 35%, doubling the expected rate due to delayed onset and subsequent deployments. The Institute for Operations Research and the Management Sciences calls for increased mental health resources to care for returning troops.
A study published in the Bulletin of the American Meteorological Society suggests that the 1918 El Niño may have contributed to the severity of the flu pandemic. The research indicates that the El Niño was one of the strongest of the 20th century, and its impact on global weather patterns could have exacerbated the spread of the disease.
A national study of over 42,000 children with head trauma found that one in five over 2 and nearly one-quarter under 2 did not need CT scans due to low-risk brain injury. The study provides guidelines for doctors to safely reduce CT use in these patients, aiming to minimize radiation exposure risk.
A study examined stroke risk among patients undergoing cardiac surgery, finding that post-operative stroke occurred in approximately 2 percent. Patients with combined cardiac and carotid procedures had a significantly higher incidence of postoperative stroke, suggesting that these procedures should be avoided.
High-resolution 3D images of polymer solar cells reveal new insights into their nanoscale structure and effect on performance. Researchers shed light on operational principles, highlighting potential for cost-effective, flexible, and lightweight technology.
A new sensor array can detect multiple airborne toxins in a matter of seconds, providing essential monitoring for workers handling chemicals. The technology uses colorimetric sensors that are not affected by humidity, making it more reliable than previous electronic-nose technologies.
Studies suggest that genetic factors, particularly those related to monoamine neurotransmitters, may contribute to the development of conduct disorders. Variations in genes encoding enzymes such as MAO-B have been linked to increased risk of antisocial behaviour, with associations strengthening when environmental factors are considered.
Researchers have identified the 'master gene' E4bp4, which drives blood stem cells to produce disease-fighting Natural Killer immune cells. The discovery could lead to new ways to treat cancer and autoimmune diseases by boosting the body's production of these frontline tumour-killing cells.
Researchers identified two proteins, C/EBPα and β, that control the transition from stem cell to skin cell development in mice. Mice lacking these proteins had defective skin formation and died shortly after birth. The study sheds light on the mechanisms involved in skin cancer and other epithelial cancers.
The University of Utah has developed a two-minute water quality monitoring method that uses a handheld color sensor to detect iodine or silver levels in drinking water. The system is designed to be simple, low-cost and safe for use on the International Space Station.