Researchers at Cold Spring Harbor Laboratory discovered that two non-coding RNAs, MENε and MENβ, trigger the formation of nuclear subcompartments called paraspeckles. Paraspeckles are believed to serve as storage depots for pre-made protein-coding RNA, allowing cells to respond faster to stress.
Australian researchers have developed a method to analyze X-ray scattering data from XFELs, enabling the measurement of membrane protein structures even with significant electronic damage. This breakthrough will help fast-track the development of targeted drugs.
The innate immune system deploys two effective strategies to deal with invasive bacterial infections, including an emergency backup plan involving interleukin-1 beta (IL-1β), which stimulates white blood cell production. However, this backup system can also lead to chronic inflammation and organ damage if not managed properly.
Patients who develop an acne-like skin rash after starting chemotherapy and cetuximab treatment have better overall survival, progression-free survival, and response rates compared to those without a rash. The study suggests that an early skin rash could be a predictor of treatment success in lung cancer patients.
Researchers at UC Berkeley have developed a new technique that allows plasmon lasers to operate at room temperature. This achievement is a major step towards applications for plasmon lasers in single-molecule biodetectors, photonic circuits, and high-speed optical communication systems. The scientists were able to enhance the emission ...
A team of scientists at MIT has deciphered 3 billion-year-old genomic fossils using modern-day genomes. The study reveals that the collective genome of all life underwent an expansion between 3.3 and 2.8 billion years ago, resulting in 27% new gene families.
A team of scientists identified a set of brain proteins that accounts for over 130 brain diseases, including Alzheimer's and Parkinson's. The study provides a new way to study the evolution of the brain and behavior, and opens paths toward tackling these diseases.