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Science News for January 11, 2010


UC Davis study: Butterflies reeling from impacts of climate and development

A new analysis led by UC Davis expert Arthur Shapiro reveals that climate change and habitat loss are devastating butterfly populations, with lowland species being hit hard. The study's findings also show that 'ruderal' butterfly species, often considered insignificant, are declining faster than other species.

SourceUniversity of California - Davis·JournalProceedings of the National Academy of Sciences·DateJan 11, 2010

Got cognitive activity? It does a mind good

A large national study from Brandeis University found that intellectual activities undertaken regularly can make a difference in maintaining memory. Those with low education who engaged in reading, writing, attending lectures, doing word games or puzzles regularly had memory scores similar to people with more education

SourceBrandeis University·JournalAmerican Journal of Geriatric Psychiatry·DateJan 11, 2010

Captured by true crime

Research in Social Psychological and Personality Science suggests that women's fascination with true crime stems from a desire to learn strategies for prevention and survival. The study found that women are more likely to be drawn to true crime books than men, as they seek to understand warning signs and escape tips.

SourceSAGE·JournalSocial Psychological and Personality Science·DateJan 11, 2010

Discovery provides new drug targets for malaria cure

Researchers have identified a set of proteins related to the malaria parasite that can serve as new drug targets. The discovery uses a plant-based model, Arabidopsis, to understand how these proteins normally function, which could lead to the development of more effective antimalarial drugs.

SourceUniversity of Melbourne·JournalProceedings of the National Academy of Sciences·DateJan 11, 2010

JCI online early table of contents: Jan. 11, 2010

Researchers question the safety of gene therapy targeting I-1c in treating heart failure after finding it can cause abnormal heartbeats and sudden death. Additionally, a study reveals that certain anticancer drugs can cause heart failure by triggering PDGFR-beta signaling in heart muscle cells.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJan 11, 2010

A solid case of entanglement

Researchers have successfully demonstrated quantum entanglement in solid-state devices, a breakthrough that could enable faster and more secure computing. The experiment uses electrons in a superconductor to create entangled pairs, which can be used to enhance computing performance and secure data transmission.

SourceAmerican Physical Society·JournalPhysical Review Letters·DateJan 11, 2010

Microbe understudies await their turn in the limelight

A team of scientists has discovered that rare microbial organisms, once thought to be undetectable, dominate the ecosystem in a unique hydrothermal vent field. The study, led by William Brazelton at the University of Washington, found that microorganisms can remain rare for long periods before becoming dominant when ecosystems change.

SourceUniversity of Washington·JournalProceedings of the National Academy of Sciences·DateJan 11, 2010

Program may prevent knee injuries in young female soccer players

A soccer-specific exercise program reduced the risk of knee injuries among young female players by 77%, according to a study published in Archives of Internal Medicine. The program, which included strengthening exercises and awareness training for coaches and parents, also resulted in less severe injuries when they did occur.

SourceJAMA Network·JournalArchives of Internal Medicine·DateJan 11, 2010

Small amounts of lead may damage children's kidneys

A Johns Hopkins Children's Center study found that even small amounts of lead in healthy children's bodies can impair kidney function, with those having higher levels showing decreased kidney filtration rates. The researchers measured kidney function using two tests and found a link between higher lead levels and worse kidney function ...

SourceJohns Hopkins Medicine·JournalArchives of Internal Medicine·DateJan 11, 2010

One-third of NFL players with Achilles tendon injuries sidelined

Research in the Foot & Ankle Specialist journal found that Achilles tendon ruptures can be career-altering injuries for NFL players. Nearly 36% of players who sustained this injury never returned to play in the NFL, with those who did return experiencing a significant reduction in power ratings.

SourceSAGE·JournalFoot & Ankle Specialist·DateJan 11, 2010

New ways to pressure HIV

Researchers found that unique reading frames in the HIV genome can induce immune responses, potentially leading to new ways to combat the virus. These findings may prove useful for developing more effective HIV vaccines.

SourceRockefeller University Press·JournalJournal of Experimental Medicine·DateJan 11, 2010

Considering the evidence in health care

A study published in International Journal of Public Policy suggests that an evidence-based approach to medicine can increase quality and efficiency of healthcare systems. This approach emphasizes using medical research literature to inform clinical decisions.

SourceInderscience Publishers·JournalInternational Journal of Public Policy·DateJan 11, 2010

Climate conditions in 2050 crucial to avoid harmful impacts in 2100

A new study suggests that policymakers should focus on achieving mid-century emission targets to preserve long-term options for avoiding dangerous levels of warming. The research identifies critical mid-century thresholds that would make particular goals unachievable with current energy technologies.

SourceNational Center for Atmospheric Research/University Corporation for Atmospheric Research·JournalProceedings of the National Academy of Sciences·DateJan 11, 2010

Neuroimaging may shed light on how Alzheimer's disease develops

Researchers use Positron Emission Tomography (PET) to image amyloid-beta protein plaques in the brain, detecting deposits in cognitively normal older subjects and associating them with brain atrophy. The findings suggest a critical early role for amyloid deposition in Alzheimer's disease development.

SourceIOS Press·JournalBehavioural Neurology·DateJan 11, 2010

Breast cancer multigene test helping patients avoid chemotherapy

A new 21-gene test is helping doctors and patients make informed treatment decisions by predicting whether chemotherapy is necessary for early-stage breast cancer. The test, which examines tumor gene activity, has led to changes in treatment recommendations in 31.5% of cases, with most changes favoring avoidance of chemotherapy.

SourceLoyola Medicine·JournalJournal of Clinical Oncology·DateJan 11, 2010

Biologists merge methods, results from different disciplines to find new meaning in old data

Researchers argue that combining concepts and tools from multiple disciplines can yield new findings, citing examples such as J. John Sepkoski Jr.'s database of fossil records and synthetic paleobiology. The authors also highlight the potential of integrating methods, conceptual synthesis, and re-use of results to transform science.

I-1c gene therapy: Not such a good idea in heart failure?

Researchers found that gene therapy to express a constitutively active form of protein I-1c in heart muscle cells improved contractile function in young mice, but led to abnormal heartbeats and sudden death under stress. Older mice developed characteristic features of heart failure after treatment.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJan 11, 2010

Researchers trace HIV mutations that lead to drug resistance

Researchers have developed a novel way to trace mutations in HIV that lead to drug resistance. By comparing sequences of HIV from treated and untreated patients, they identified clusters of mutations that help the virus escape treatment. This breakthrough could enable doctors to tailor drug cocktails to individual patient strains.

SourceUniversity of California - San Diego·JournalProceedings of the National Academy of Sciences·DateJan 11, 2010

Study shows that delivering stem cells improves repair of major bone injuries in rats

A study published in PNAS found that delivering stem cells on a polymer scaffold to treat large areas of missing bone leads to improved bone formation. However, the therapeutic effect is limited by the migration of stem cells away from the injury site, highlighting the need for improved delivery methods.

SourceGeorgia Institute of Technology·JournalProceedings of the National Academy of Sciences·DateJan 11, 2010