A new study found significant changes in targeted genes in patients' tumors, suggesting existing therapies may benefit more cancer patients. The research identified potential targets for treatment with existing targeted therapies.
A study published in Current Directions in Psychological Science found that people with mastery goals are more open to hearing different perspectives and less deceitful, while those with performance goals are more competitive and less willing to share information. Balancing different levels of goals can help establish constructive work...
Researchers discovered that asthma drugs can block cysteinyl-leukotrienes, reducing vessel wall breakdown and dilation. This could lead to the development of new treatments for aortic aneurysms, potentially saving lives and reducing surgical complications.
A new study by Radiological Society of North America suggests that routine mammography screening in women over 40 has a very low risk of radiation-induced breast cancer. The study found that annual or biennial screening would result in few cancers and fatalities, but numerous lives saved through early detection.
A new study from UC Berkeley found that dire warnings about global warming can backfire, making people skeptical and resistant to change. However, presenting solutions and less apocalyptic ways of communicating findings can overcome skepticism. The research suggests fear-based appeals can undermine efforts to address climate change.
Researchers at the University of Cincinnati have identified a protein called HAX-1 that protects cardiac cells and muscle from damage during ischemia-reperfusion injury. The study found that HAX-1 levels were reduced in hearts after heart attack, but overproduction improved contractile performance and decreased cell death.
A team of researchers has developed a way to prevent cavitation damage in jet fuel pumps, essential components in modern aircraft. The study provides realistic data for computer models, enabling designers to create lighter, more efficient, and longer-lasting pumps.
A unique program in East Harlem helps middle school students learn practical health skills, resulting in increased interest in college attendance and medical careers. The MedStart Summer Enrichment Program improves student knowledge of diseases prevalent in their community, such as asthma and diabetes.
Dr. Jay Kolls has been recognized with the prestigious MERIT Award for his work on a discovery that plays a critical role in the body's defense against pneumonia. His research uses genetically engineered mice to investigate the role of lung epithelium and explore how cells control infection defense in the lung.
Using OncoMap, researchers can identify specific mutations in oncogenes that drive ovarian cancer growth and choose targeted drugs to halt tumor progression. The technique holds promise for personalized medicine in treating advanced ovarian cancer.
A recent study by Dr. Nan Yao and his team found that carbon nanotubes induced programmed cell death in plant cells, with the effect being dosage-dependent. The researchers discovered that only single-wall carbon nanotubes caused cell damage, while other types of particles did not.
A new study presents the first geological evidence that the ancestors of C4 grasses emerged millions of years earlier than previously established. Researchers analyzed carbon isotope ratios in individual grains of grass pollen, finding unequivocal evidence for C4 grasses in southwestern Europe by the Early Oligocene.
A Princeton scientist has recast two well-known math problems as physics questions, providing new tools for solving challenges in data compression, gravitational waves, and more. The reformulation offers insights into the role of randomness and disorder.
Researchers at NC State University have discovered a cost-effective method to deter deer from damaging Christmas trees. By using inexpensive, inedible food byproducts like dried blood and egg powder, farmers can protect their crops with significant savings.
Researchers have found a dozen double-star systems consisting of two white dwarfs, with half expected to merge and explode as supernovae. The merged stars will stir space-time, creating gravitational waves and causing them to spiral closer together.
UC San Diego undergraduate bioengineers develop a new microenvironment that provides all three types of cues necessary for stem cell growth and differentiation. The system uses a gelatin-like hydrogel bathed in an electrolyte solution, mimicking the natural environment to steer stem cells towards specific cell types.
The FRAX tool was clarified for its use in clinical practice through international discussions, enabling its wider implementation. The tool predicts a patient's 10-year fracture risk based on scientifically validated risk factors.
Duke University Medical Center will oversee external quality assurance programs for HIV laboratories worldwide, ensuring reliable and reproducible data for treatments, under a $52.8 million NIH contract. The project aims to address global laboratory standards, tracking virus strains and assays for new therapies.
A UC Riverside-led team is working on a project to educate students about climate change using real-world NASA data. The initiative aims to improve communication skills among students and scientists, crucial in addressing climate change issues.
A six-year study on migrating geese found that young birds learn their migratory destinations from parents, demonstrating a high concentration of related birds. This cultural inheritance may provide advantages such as better access to food and reproductive success.
A new study found that automated remote patient monitoring did not improve outcomes for heart failure patients, despite daily interactions with healthcare clinicians. The system was compared to usual care based on national guidelines and showed no effect on hospitalization rates or mortality.
A study led by Howard Ochman found that host species, rather than diet, have the greatest effect on gut bacteria diversity in great apes. The researchers discovered that bacterial populations assorted to species and matched the relationships of their host, indicating a long history of co-evolution.
A randomized phase 2 study found that combining sorafenib with doxorubicin improved median overall and progression-free survival in patients with advanced liver cancer. The study showed a significant reduction in the risk of death and progression, with median overall survival increasing to 13.7 months
A national pilot program utilizing a Carnegie Mellon-developed algorithm is matching living kidney donors with medically compatible transplant candidates. The initial run of the computer matching process successfully matched seven people in need of a kidney transplant with suitable donors, expanding kidney paired-donation transplants.
A study by Rush University Medical Center researchers found structural brain changes in individuals at risk for Alzheimer's disease. Those who progressed to the disease showed thinning of cortical areas receiving input from a specific brain region.
Researchers have developed an advanced imaging technology to rapidly screen single-wall carbon nanotubes, which could be used in creating a new class of computers and electronics. The technique, called transient absorption, measures the metallicity of the tubes and may be combined with another laser to zap unwanted metallic nanotubes.
A new study published in Alcoholism: Clinical & Experimental Research found that adolescent males who engage in heavy drinking are more likely to exhibit risk-taking behavior. The research followed over 500 first-grade boys from Pittsburgh until age 20 and found a significant correlation between heavy drinking and impulsive behavior.
A new inhalable dry powder treatment for lung cancer has been shown to significantly increase survival rates, with over 80% of mice surviving for more than 90 days. The treatment method is also less invasive than traditional options, reducing the risk of side effects and improving overall patient outcomes.
The American Association of Pharmaceutical Scientists (AAPS) has named 18 individuals as its 2010 Fellows, honoring their remarkable scholarly and research contributions. The new fellows include researchers who have made significant advances in drug delivery, pharmacokinetics, and cancer therapy.
A study by University of Wisconsin-Milwaukee researchers found that teleworkers experience fewer work-life conflicts and less job stress compared to their office-based colleagues. These benefits lead to higher job satisfaction for telecommuters.
A new task force in Leicester will develop a tailored management and intervention programme for asthma in South Asian children, informed by community views and experiences. The project aims to improve access to services and self-management of asthma amongst this community.
A Stanford University School of Medicine study suggests an alternative to standard nasal sprays that use preservatives, which can cause side effects. The new method maintains sterility in the applicator bottle without chemical preservatives.
Researchers have developed racetrack memory, which uses magnetic tape and spin-polarized currents to store data at speeds of several hundred meters per second. This technology could enable computers to boot up instantly and access information 100,000 times more rapidly than traditional hard disks.
A recent study published in PNAS reveals the unique role of EZH2 enzyme in cancer, facilitating the development of selective small molecule therapeutics for specific forms of human lymphomas. The research highlights the importance of targeting HMTs in genetically-defined cancer patients with high unmet needs.
Researchers have developed ultra-short X-ray beams that rival those made in expensive synchrotron particle accelerators, opening up new research possibilities. These beams can be used to measure and observe never-before-seen femtosecond atomic and molecular interactions.
Researchers at UT Southwestern Medical Center have discovered a feedback cycle involving microRNAs, proteins called ZEB1 and ZEB2, and pregnancy-maintaining hormone progesterone. MicroRNA levels increase before labor, enabling uterine contractions.
The global burden of disease associated with poor hygiene, sanitation, and water supply is substantial, accounting for nearly 20% of all child deaths worldwide. Four papers in the PLOS Medicine series highlight the need for urgent action to improve access to safe drinking water, sanitation facilities, and hand-washing practices.
Researchers from the University of Gothenburg have discovered a new drumlin field, revealing that modern-day glaciers can create these geological formations. The study provides evidence of rapid ice movements and challenges current climate modeling techniques.
The seven-year project aims to reduce obesity and high blood pressure by increasing physical activity, healthy eating, sleep, and stress management in overweight and obese students. It will assess the effectiveness of three behavioral interventions within children's school and community environments.
Researchers at the Centenary Institute discovered a new death pathway that can break drug resistance in ovarian cancer. The treatment, FTY720, kills ovarian cancer cells through necrosis, making it resistant to relapse. Further clinical trials are needed to confirm its effectiveness.
A recent study by Intermountain Medical Center Heart Institute reveals that over half of patients taking warfarin are unaware of potential interactions with herbal and dietary supplements. The most commonly used supplements interfere with the effectiveness of warfarin, increasing the risk of bleeding or stroke.
Researchers used phylogenetic analysis to pinpoint the source of HIV infections in two separate cases, revealing that defendants knowingly spread the virus to multiple partners. The study demonstrates the potential for evolutionary forensics to exonerate falsely accused and convict those responsible.
A new study found that most teachers' value-added impact on students' math and reading scores decreases rapidly, with 73% of math gains fading within a year. Researchers analyzed data from over 1.3 million student test scores in North Carolina schools.
Researchers at Duke University Medical Center discovered a novel feedback mechanism controlled by the Zif protein that regulates the balance of brain stem cells. This discovery has implications for understanding neural stem cell self-renewal and may lead to new therapies against brain tumors and diseases.
A study of Neanderthal and early human teeth reveals that modern humans' slow development and long childhood are recent traits. This may have given early humans an evolutionary edge over Neanderthals, facilitating additional learning and complex cognition.
Researchers found that hormone therapy has no effect on prostate size in middle-aged men, while a study on presumed consent policies suggests it may increase deceased kidney donation rates but lower living donor rates. Additionally, high co-pay costs are linked to increased prescription abandonment rates, highlighting the need for affo...
Researchers developed a comprehensive genetic test that can screen all 54 known deafness-causing genes in one run, costing $2,000. The new OtoSCOPE test offers quicker answers for families anxious to determine treatment options or learn the likelihood of future children having hearing loss.
The Himalayan region's glaciers are retreating, but the impacts of climate change will still be felt, with programs integrating health, education, and social organizations needed to address these effects. The report highlights the need for international collaboration to gather more information on glacier ice balance.
A study found that various types of C. difficile are now common across European hospitals, with an average incidence rate of 4.1 per 10,000 patients per day. The most prevalent types were 014/020, 001, and 078, with type 027 being less common in Europe compared to other regions.
A new study reveals that APP695 is the primary source of amyloid-beta peptide, a toxic compound contributing to Alzheimer's disease. This discovery enables researchers to target their work more precisely, potentially leading to a better understanding and treatment of the disease.
Researchers at Mayo Clinic have shown that iron buildup is prevalent in unstable coronary artery plaque, making it a potential marker for risk of myocardial infarction and sudden death. Non-invasive imaging techniques, such as micro-CT scans, may soon be able to detect these plaques, allowing for earlier intervention.
The Graph500 test aims to measure a computer's ability to analyze large graph-based structures, which are increasingly used in biological, social, and security problems. The test is designed to influence computer makers to build computers with the architecture needed to handle these complex applications.
Non-smokers exposed to tobacco smoke are at risk of hearing loss, with men and older individuals more likely to experience high-frequency hearing loss. Even low levels of passive smoking can continue the progression of hearing loss in former smokers.
A new study suggests that human creativity may have evolved as a way for parents to bond with their children, passing on cultural knowledge and traditions. This theory challenges the idea that creativity emerged from courtship behaviors, proposing instead that it arose from parental influences.
A preservative-free, acidified nasal spray was found to be safe and effective at maintaining sterility in a small-scale study. The researchers evaluated the spray's impact on symptoms and microbial growth, finding no significant differences between the preservative-free and preservative-containing options.
A study involving 30 patients found that robotic-assisted surgery can be performed safely with minimal blood loss and no significant long-term complications. The surgeries took an average of 512 minutes, but the rates of postoperative deaths, fistulas, and complications were comparable to those in open procedures.
The American College of Medical Informatics (ACMI) has inducted eight new Fellows, who have made substantial and sustained contributions to the field of medical informatics. The incoming ACMI President, Jim Cimino, welcomed the new Fellows, praising their expertise in clinical practice, medical research, education, and patient care.
Researchers at the University of Cincinnati have developed a stem cell-infused patch that promotes cell migration to damaged cardiac tissue following a heart attack, resulting in improved function. The patch combines cardiomyocytes, endothelial cells, and embryonic fibroblasts to enhance regeneration of heart tissues.
Researchers observe sills forming at shallow depths in sediment layers, releasing nutrient-rich fluids and significant amounts of CO2 and methane. This novel mechanism may influence ocean cycles and climate.
A Nova Southeastern University researcher has discovered a novel method using gene therapy to block beta-arrestin 1, a protein that contributes to heart failure. The approach aims to reduce the severity of heart failure by targeting the increase of aldosterone production in the body.