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Science News for September 13, 2010


Focus on photonics

The Arizona State University Center for Photonics Innovation will focus on semiconductor photonic materials and devices, with applications in various fields. The center aims to engage researchers from diverse specialties, promote entrepreneurship development, and provide opportunities for graduate and undergraduate students.

JCI online early table of contents: Sept. 13, 2010

Researchers discovered an indirect approach to reducing JAK2 activity by targeting HSP90, which stabilized JAK2. This treatment normalized blood counts and improved survival in mouse models of myeloproliferative neoplasms. Inhibiting c-Met also decreased mTOR signaling and blocked cyst formation in a mouse model of autosomal dominant p...

SourceJCI Journals·JournalJournal of Clinical Investigation·DateSep 13, 2010

New pathway identified in Parkinson's through brain imaging

Researchers at Columbia University Irving Medical Center have identified a novel molecular pathway underlying Parkinson's disease, which involves polyamines and toxic proteins in neurons. The study suggests that polyamine-lowering drugs may be able to slow the disease's progression and potentially lead to early detection tests.

SourceColumbia University Irving Medical Center·JournalProceedings of the National Academy of Sciences·DateSep 13, 2010

Wildflower 'armors' itself against disease

Scientists from Oxford University found that Alpine pennycress plants accumulate zinc, nickel, and cadmium to defend against bacterial infection. The study demonstrates a direct link between metal concentrations and resistance to disease.

SourcePLOS·JournalPLOS Pathogens·DateSep 13, 2010

USGI medical tissue anchors show durability beyond 1 year

The USGI medical tissue anchors have demonstrated long-term durability beyond 1 year in various incisionless gastrointestinal procedures. The anchors enable surgeons to perform scarless surgeries through the mouth, reducing pain and hospital stays. No serious adverse events were reported during the 24-month follow-up endoscopies.

SourceUSGI·JournalObesity Surgery·DateSep 13, 2010

Signaling hope for polycystic kidney disease

Researchers identify hyperactive c-Met protein as key player in ADPKD cyst growth, leading to potential therapeutic target. Pharmacological inhibition of c-Met decreases mTOR activity and blocks cyst formation in mouse model.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateSep 13, 2010

A new target in polycystic kidney disease

Researchers at Boston Children's Hospital discovered a new approach to treating polycystic kidney disease by inhibiting c-Met receptor activity, reducing cyst size and number. The compound showed promise in animal models, potentially leading to clinical trials in humans.

SourceBoston Children's Hospital·JournalJournal of Clinical Investigation·DateSep 13, 2010

Can the kids be all right if they are gay too?

Research on LGBTQ families reveals that their children are not only psychologically healthy but often excel in social and academic areas. However, Family Therapist Arlene Istar Lev suggests that this success might be masking a bias against LGBTQ individuals, who face societal pressure to produce heterosexual offspring.

SourceWiley·JournalFamily Process·DateSep 13, 2010

Welsh scientists 'clone' human virus

Researchers at Cardiff University cloned a human virus, Human Cytomegalovirus (HCMV), which is a major cause of congenital malformations and life-threatening disease in transplant patients. The cloning of HCMV has enabled the development of new treatments and vaccines against this virus.

SourceCardiff University·JournalJournal of Clinical Investigation·DateSep 13, 2010

Male maturity shaped by early nutrition

A new Northwestern University study found that rapid weight gain in the first six months of life predicts earlier puberty for boys and has long-term effects on their physical characteristics and reproductive strategy. The researchers suggest that testosterone plays a key role in shaping these differences.

SourceNorthwestern University·JournalProceedings of the National Academy of Sciences·DateSep 13, 2010

'Hi-JAK-ing' cancer by inhibiting Jak2

Researchers describe an indirect approach to reducing JAK2 activity by pharmacologically targeting HSP90. Inhibiting HSP90 normalized blood counts and improved survival in two mouse models of MPN, promoting JAK2 degradation in samples from patients with the disease.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateSep 13, 2010

Children and adults see the world differently

Research published in Proceedings of the National Academy of Sciences suggests that children under 12 do not combine different sensory information like adults, and this ability develops around age 12. Adults can integrate multiple sources of visual information, such as perspective and binocular depth, to make a unified estimate.

SourceUniversity College London·JournalProceedings of the National Academy of Sciences·DateSep 13, 2010

Blacks with muscular dystrophy die 10-12 years younger than whites: New study

A new study reveals that African Americans with muscular dystrophy face a significant mortality gap compared to their white counterparts, largely due to unequal access to quality healthcare and insurance coverage. This widening disparity is attributed to systemic inequalities in the healthcare delivery system and the effects of inadequ...

Information patients use to pick physicians not always good predictor of quality, study finds

A study from RAND Corporation and University of Pittsburgh School of Medicine found that three characteristics - being female, board certified, and graduating from a domestic medical school - had a small association with better quality medical care. However, these findings highlight the need for better physician performance data to hel...

SourceRAND Corporation·JournalArchives of Internal Medicine·DateSep 13, 2010

Avoiding an asteroid collision

Researchers at Tel Aviv University have verified a theory that asteroid pairs are formed when small gravel-sized rocks separate from a larger asteroid through centrifugal force. The study, published in Nature, reveals that these 'separated asteroids' share the same orbit and demonstrate the existence of paired asteroid relationships.

International Fertility Societies call for harmonization of cross-border reproductive care standards

The European Society of Human Reproduction and Embryology and the International Federation of Fertility Societies are concerned about the lack of uniform clinical standards between countries, putting patients' safety at risk. The societies are developing a 'Code of Practice on Cross Border Reproductive Care' to protect and reassure pat...

SourceEuropean Society of Human Reproduction and Embryology·JournalFertility and Sterility·DateSep 13, 2010

If the water looks and smells bad, it may be toxic

A USGS study found that taste-and-odor compounds are commonly associated with cyanotoxin presence, highlighting the need for increased surveillance and public alert systems. Cyanotoxins can be poisonous to people, aquatic life, pets, and livestock, causing symptoms like skin rashes, stomach upset, seizures, or death.

SourceU.S. Geological Survey·JournalEnvironmental Science & Technology·DateSep 13, 2010

September/October 2010 Annals of Family Medicine tip sheet

Research reveals nearly half of patients who initiated biennial fecal occult blood test screening did not adhere to subsequent colorectal screening. In contrast, depression management programs delivered promising long-term results for chronically depressed primary care patients. The study also found modest reductions in branded drug us...

SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateSep 13, 2010

New insight into 'accelerated aging' disease

A study published in Developmental Cell sheds light on Hutchinson-Gilford Progeria Syndrome, a rare genetic disease causing premature aging. Researchers discovered that defects in the extracellular matrix and Wnt signaling pathway contribute to progeria's characteristic symptoms.

SourceCell Press·JournalDevelopmental Cell·DateSep 13, 2010

Wives as the new breadwinners

Research suggests wives are more likely to enter labor force when husbands stop working during economic downturn, highlighting shifting gender roles in families. Jobs in health and education industries provide a reliable source of income for families during recession.

SourceWiley·JournalFamily Relations·DateSep 13, 2010

Your body recycling itself -- captured on film

McGill researchers discovered how cells identify and recycle proteins by capturing an image of the UBR box component. This finding holds promise for understanding and treating Johanson-Blizzard syndrome, a rare disease causing deformations and mental retardation.

SourceMcGill University·JournalNature Structural & Molecular Biology·DateSep 13, 2010