Researchers discovered a long non-coding RNA (lncRNA) that prevents programmed cell death in maturing red blood cells, a process linked to leukemias and cancers. This lncRNA may represent a new avenue of attack for therapeutics.
A new report by the University of Victoria finds that most eco-labels for farmed marine fish offer less than a 10% improvement in environmental performance compared to conventional practices. The study evaluates 20 eco-labels, ranking them based on numerical scores derived from a well-established quantitative methodology.
Researchers have created two new methods to treat overeating in children and adults, focusing on internal hunger and satiety cues. The 'appetite awareness' group trained participants to regulate eating by monitoring their hunger and satiety cues, while the 'cue exposure' group taught them to tolerate cravings to reduce overeating.
A recent study published in the Journal of Agriculture and Food Chemistry has evaluated a new method for determining protein quality. Soy protein was found to be a high-quality protein with a PDCAAS score of 1.00, comparable to animal-based proteins like eggs, dairy, and meat.
Researchers at Queensland University of Technology developed a novel CAD system to create accurate moulds for breast reconstruction surgery. Three patients reported higher satisfaction rates after successful surgeries using the technology.
A new predictive tool has been developed to assess the risk of recurrence in gastrointestinal stromal tumours (GIST) following surgery. The tool provides more accurate prognosis for individual GIST patients compared to conventional models, helping to identify those most likely to benefit from additional treatment.
Women treated with brachytherapy experienced a twofold increased risk for losing their breasts compared to those treated with whole-breast irradiation. Brachytherapy also led to nearly a twofold higher risk of postoperative infections and complications, as well as radiation-related side effects.
A research team discovered distinct gene patterns associated with early and late breast cancer recurrences, which could help predict patient outcomes and guide personalized therapy. The findings may enable oncologists to delay or prevent recurrences and reduce excessive treatment for patients who will not recur.
A new study from the University of Gothenburg found that dental X-rays can predict who is at risk of fractures. The research used data from a long-running Prospective Population Study of Women in Gothenburg and showed that people with sparse bone structure in their jaw are more likely to experience fractures, particularly as they age.
The Virginia Tech – Wake Forest University School of Biomedical Engineering and Sciences has received two new research projects from Toyota's Collaborative Safety Research Center. The projects aim to improve the understanding of traumatic brain injuries and abdominal injuries, with a focus on reducing risk in automobile impacts and foo...
Researchers found that patients with fatty livers burn more fat and produce glucose faster than those with healthy livers, potentially leading to organ damage. The study's findings challenge previous assumptions about the role of metabolism in fatty liver disease.
Research by Jean Malpas finds that a normal diversity of gender expression exists among children, who may identify as transgender or non-binary, and that multi-dimensional support is crucial for acceptance and protection
A large study published in PLOS Medicine has found a positive association between rotating night shift work and the risk of developing type 2 diabetes in women. The study, which analyzed data from over 230,000 women, suggests that long duration of shift work may also be associated with greater weight gain.
A team of Penn researchers has discovered that the evolution of the TAS2R38 gene, responsible for bitter taste perception, was driven by factors other than taste. The study found that African populations have a broader range of PTC taste sensitivity and unique genetic variants not seen in non-Africans.
A team of four early-career researchers from the University of Oxford emerged as winners of this year's Biotechnology Young Entrepreneurs Scheme (YES) competition. They impressed investors with their idea for using yeast to produce high-value fragrance components. The competition aims to raise awareness of commercialization amongst bio...
Researchers from Indiana University School of Medicine have made a breakthrough using century-old brain samples to detect mental illness. The goal is to create a simple blood test for conditions like bipolar disorder, schizophrenia, and PTSD, which could lead to faster diagnoses and improved patient care.
WHOI scientists Henry Dick and Joe Pedlosky received prestigious medals from the American Geophysical Union. Dick was awarded the Harry H. Hess Medal for his work on the mantle melting and ocean crust formation along global ocean ridges.
A devastating 'founder effect' genetic disorder has been identified as causing defects in mitochondrial energy production in cerebellar neurons. This leads to the development of a debilitating neurodegenerative disease characterized by progressive damage and coordination problems, ultimately resulting in significant disability.
Researchers at the University of Liverpool found that diabetic pregnant women experience weaker uterine contractions, increasing the risk of emergency caesarean births. Calcium levels in the uterus are also significantly reduced in these women, leading to poorly contracting muscles.
A new study shows that Indian and Vietnamese immigrants in Texas develop a unique American identity through community participation and civic engagement. They deepen their American identity by engaging in various activities such as festivals, banquets, and volunteer work, without losing their cultural heritage.
Astronomers have found two massive black holes, each with a mass of 10 billion suns, in nearby galaxies. These 'sleeping giants' are thought to be remnants of quasars that powered matter into black holes in the early universe.
A new study found that human brain development differs from chimpanzees and macaques, with hundreds of genes showing unique developmental patterns in the prefrontal cortex. MicroRNA activity patterns also showed significant differences, potentially linked to human-specific changes in cognitive abilities.
The NIST SCUBA-2 camera is the world's largest submillimeter camera, containing over 10,000 superconducting sensors. It will enable faster and more accurate mapping of the sky, producing better images and sky maps.
A four-year study assesses freshwater resources in the High Asia region, encompassing five mountain ranges and watersheds totaling 1 million square miles. The research aims to provide accurate data on snow and glacier contributions to river discharge, helping forecast water resource availability and vulnerability.
Researchers found that high levels of inflammation significantly shorten white dialysis patients' lives, but African Americans with similar inflammation levels survive similarly. A new study aims to understand and possibly mitigate this survival difference.
A new study reveals four distinct configurations of the SBP8a bacteriophage, showing its ability to penetrate anthrax cells and control DNA flow. The discovery provides an initial blueprint for modifying the phage into a detection tool for anthrax and other bioterror agents.
Research suggests that tropical sea-surface temperatures may contribute to accelerated melting of Antarctic glaciers, such as Pine Island and Thwaites, due to westerly winds. This phenomenon is linked to changes in atmospheric circulation influenced by warmer-than-usual sea-surface temperatures in the central tropics.
Researchers at the University of Alabama, Birmingham have found that mutations in primary cilia can disrupt the functioning of the melanin concentrating hormone receptor, leading to increased appetite and weight gain. This discovery sheds light on the potential link between ciliopathies, such as Bardet-Biedl syndrome, and obesity.
INT-777 prevents atherosclerosis by exerting an anti-inflammatory effect, stimulating insulin secretion and reducing plaque formation in arteries. The compound activates TGR5 receptor in gut cells, enhancing Glucagon-Like Peptide-1 (GLP-1) secretion, providing a promising treatment for metabolic syndrome and its associated conditions.
USDA scientists found that using insecticides specifically targeting whiteflies can reduce the need for broad-spectrum pesticides. The study showed that applying a single dose of whitefly-specific insecticide can control whitefly populations for the rest of the growing season.
Researchers at Purdue University have created a new type of transistor with a 3-D structure, potentially leading to faster, lighter laptops. The transistors contain nanowires made from indium-gallium-arsenide and have the potential to conduct electrons five times faster than silicon.
Research by Wally Carlo found that antenatal corticosteroids significantly reduce mortality and neurodevelopmental impairments in extremely preterm infants from 22 to 25 weeks gestation. The study showed a 33% decrease in mortality and a 20% decrease in neurodevelopmental impairments.
A new species of horned dinosaur named Spinops sternbergorum was discovered nearly 100 years after its initial discovery in southern Alberta, Canada. The animal lived approximately 76 million years ago and weighed around two tons, featuring a unique bony neck frill with long spikes.
Whole genome sequencing technology has arrived, uncovering both useful and unwelcome medical results, including information on high-risk diseases like dementia. Regulation is crucial to ensure safe use, with a nuanced approach that balances paternalism with protection from potential harm.
Research found that diabetes increases breast cancer risk by 37% in women diagnosed within four years of cancer development. Obesity after age 60 also significantly increases the risk, with a 55% increase in breast cancer cases compared to the general population. High and low blood lipids were also associated with different risks.
Researchers reconstructed climate sensitivity over five ice-age cycles using a global suite of records, comparing it with changes in greenhouse gas concentrations and Earth-Sun orbital configuration. The study estimates a 3.1-3.9°C temperature increase for a modern doubling of atmospheric carbon-dioxide concentrations.
A study found significant gene expression patterns among tumor samples that correlated with distant metastatic disease development. These patterns may help personalize treatment and predict which patients are likely to recur early or late.
A UK study reveals injuries have a much greater impact on people's lives than previously estimated, with a total of 1,771,486 disability-adjusted life years (DALYs) related to injury in 2005. The researchers found that injuries account for up to one-quarter of global DALYs if the underestimation seen in the UK is mirrored worldwide.
The NHGRI Genome Sequencing Program will prioritize medical applications and rare inherited diseases over the next four years, with a $416 million investment. The program aims to identify genetic causes of Mendelian disorders and accelerate diagnosis and treatment.
A new study found that climate change is causing humans to visit national parks earlier, with peak attendance shifting four days earlier than 30 years ago. This shift may serve as a bellwether for more severe human adjustments required to cope with climate change.
Researchers analyzed rock cores from the FAR DEEP project in Northwest Russia, finding that oxygen levels gradually increased over hundreds of millions of years. The appearance of free oxygen in the atmosphere likely occurred as a series of starts and stops, rather than a single event.
Researchers found a decrease in GABA receptor concentration in ET patients' cerebellums, which may affect motor coordination and movement control. The study opens doors to new research avenues and potential treatments for the condition.
A new grant from the National Human Genome Research Institute (NHGRI) aims to explore social and ethical issues surrounding clinical genome sequencing. The Children's Hospital of Philadelphia is one of five U.S. centers, focusing on pediatrics, to receive a four-year Clinical Sequencing Exploratory Research Project award.
Researchers from Fraunhofer ISE and CEA-LETI develop new substrate technology to reduce cost of producing multi-junction solar cells by up to 20%. This breakthrough enables more efficient and affordable solar energy solutions.
Researchers developed a multigene test to identify high-risk patients with ductal carcinoma in situ (DCIS) and differentiate between lower-risk and more aggressive forms. The DCIS Score algorithm predicts individual risk for recurrence, allowing physicians to provide tailored treatment programs.
A significant number of women with breast cancer are not receiving guideline-recommended adjuvant treatment. The research found that socioeconomic factors such as poverty, insurance status, and education level significantly contribute to this disparity. Women from high-poverty areas were less likely to receive guideline therapy, highli...
A recent study found that up to three quarters of elderly people in parts of India have vitamin C deficiency, primarily due to a low intake of fruit and vegetables. The study highlights the need to improve nutrition and discourage tobacco use among the elderly population.
The US Department of Homeland Security's DNSSEC project authenticates data existence, ownership, and integrity, protecting against hackers' threats. By deploying DNSSEC in key zones, DHS builds a safer cyberspace with complete end-to-end chain protection.
Researchers at the University of Gothenburg have discovered a brand new tick-borne infection, Neoehrlichia mikurensis, which causes Deep Vein Thrombosis (DVT) in people with impaired immune systems. The infection has been reported in eight cases worldwide, three in the Gothenburg area.
Research suggests that surprising good or bad outcomes drive learning, with neurons in the lateral prefrontal cortex and caudate nucleus processing unexpected rewards and disappointments similarly. This finding may inform future therapies to accelerate re-learning in patients with brain damage.
A new meta-analysis of randomized studies involving 4,141 prostate cancer patients found no difference in cardiovascular deaths between those receiving androgen deprivation therapy (ADT) and those who didn't. The study suggests that ADT may not increase the risk of fatal heart attacks for men without a history of heart disease.
A study on free-living female Alpine marmots found that prenatal testosterone exposure gives females an edge in a population, allowing them to become more aggressive and dominant. This is contrary to previous findings in other species, where being exposed to males can make females less reproductively successful.
Researchers found that extreme endurance exercise can cause damage to the right ventricle of the heart, which can lead to arrhythmias and reduced performance. While the damage is reversible in most athletes, five out of 40 studied showed permanent scarring, suggesting a susceptibility to long-term effects.
The Learning Designer is an interactive program that assists teachers in designing and developing lesson plans using digital technologies. It offers ideas and advice on introducing technology gradually within resource constraints, reusing existing materials, and maximizing its benefits for learners.
Steve Caplan, a scientist-novelist, presented new data on cellular endocytic trafficking at the American Society for Cell Biology's 51st Annual Meeting. His second novel, 'Welcome Home, Sir,' explores divisions between science and national identity, as well as personal struggles of an Israeli-American researcher in the US.
In a study on Trinidadian guppies, females spend time with more attractive companions to reduce harassment from males. This strategy is successful in minimizing interactions with males and increasing mating opportunities.
Researchers found that long neuropsychological tests can induce mental fatigue in healthy, athletically active subjects. The study aims to establish a baseline measurement for concussion diagnosis and prevent re-injuries by testing athletes at the beginning of their season.
A retrospective study found that women treated with accelerated partial breast irradiation therapy have a two-fold increased risk for subsequent mastectomy, most likely due to tumor recurrence or local complications. APBI brachytherapy was also associated with higher incidence of acute and late toxicities compared to traditional whole ...
Researchers found that aging human oocytes have a distinctive DNA signature that is reversed in insulin and TGF-beta mutants. In contrast, somatic cells require maintaining protein and cell quality to combat aging. The study's findings could lead to ways to delay oocyte aging and reduce birth defects.
Researchers attribute the prolonged political crisis in Belgium to divergent collective memories held by Flemish and French-speaking communities. These memories, rooted in linguistic, historical, and economic domains, have fueled mutual resentment and hindered national identity formation.