A comprehensive analysis of medical outcomes research found that few brain aneurysm patients receive specialized care at high-volume stroke centers. Patients who receive care in experienced centers are more likely to have definitive repair and good recovery.
Research reveals a strong association between stress and tumor aggressiveness in black and Hispanic breast cancer patients, compared to white patients. The study found that higher levels of psychosocial stress were linked to more aggressive tumors, suggesting potential impact on treatment outcomes.
Researchers have identified a neurotransmitter released in response to stress that stimulates the growth and migration of breast cancer cells. The study found that this neurotransmitter, norepinephrine, and its receptor NPY play a key role in the progression of breast cancer.
Columbia University researchers developed a technique to reach neurons through the blood-brain barrier using short ultrasound pulses, enabling safe and noninvasive drug delivery. The study aims to improve treatment options for devastating neurological disorders.
Researchers found that soy peptide lunasin binds to receptors in highly metastatic colon cancer cells, preventing them from attaching to the liver. Combining lunasin with chemotherapy drug oxaliplatin resulted in a sixfold reduction in new tumor sites.
A Baylor University study investigated links between Gulf War Illness (GWI) and veterans' locations during the war. GWI was most prevalent in forward areas of Iraq and Kuwait, where it was strongly associated with use of a medication given to troops to protect them from nerve agent effects.
Research found that under 16s comprise just 0.6% of national NHS patient surveys since 2004, with most young adults being less satisfied with their care than older adults
Three European medical oncologists, Johann de Bono, Rafael Rosell, and Hans Jörg Senn, have been recognized by ESMO for their groundbreaking work in prostate cancer management, lung cancer treatment, and breast cancer care. The awards celebrate their commitment to improving cancer research and clinical practice.
Research found that hospitals with higher proportions of minority trauma patients have increased odds of death, despite efforts to control for socioeconomic factors. The study analyzed 311,568 patients and found a significant link between hospital diversity and mortality rates.
A KAIST research team developed a biocompatible, flexible GaN LED that can detect prostate cancer, opening the door for implantable biomedical applications. The technology utilizes a highly efficient and flexible light-emitting device to diagnose diseases, potentially revolutionizing medical treatments.
Researchers at Harvard Medical School found that modulating Irs2 levels can slow HD progression by reducing nerve cell damage and increasing lifespan. Decreasing Irs2 levels attenuated symptoms of the disease.
A study found that treatment approaches for pediatric psoriasis differ by physician specialty and patient age, with topical medications being the primary treatment for mild cases. The researchers highlight the need for standardized guidelines to address the condition in children.
Researchers at Princeton University and NYU have developed a method to detect the collision of stars with primordial black holes, which are believed to be a source of dark matter. The new technique uses existing solar observation methods to identify subtle vibrations in a star's surface caused by a passing black hole.
Researchers have identified common genetic variants associated with the development of high-risk neuroblastoma and poor treatment outcomes in patients of African ancestry. These variants may also affect patients of other ethnic backgrounds, highlighting the importance of personalized medicine.
Researchers have discovered that the regulatory protein FoxM1 is crucial for the growth of malignant childhood brain tumors, medulloblastomas. The level of FoxM1 expressed in tumor cells significantly correlates with patient survival time, making it a useful prognostic marker to guide treatment strategies.
Data from the National Health Interview Survey shows a significant increase in mammogram screenings for immigrant women between 2000 and 2008. Despite this growth, mammography rates remain lower among foreign-born women compared to U.S.-born women.
Researchers at Imperial College London discovered that removing cholesterol from HIV's membrane prevents the virus from damaging the immune system. This finding could lead to the development of an effective HIV vaccine by boosting the adaptive response and weakening the innate immune system's overreaction.
Researchers at University of North Carolina Health Care identified genetic underpinnings of Foxp3-expressing regulatory T cells, crucial for preventing autoimmune and inflammatory disease. The study sheds light on potential therapeutic targets for diseases like type I diabetes, arthritis, and lupus.
A study using genetic analysis found that technology spread more slowly in the Americas than Eurasia, with continental orientation playing a key role. The slow diffusion of crops and technologies in the Americas can be attributed to lower latitudinal gene flow between populations.
Researchers at Children's Hospital Boston developed liposomes that can prevent HIV infection, providing a potential solution for women in resource-poor settings. The innovative technology shows great promise as a safe and effective form of prevention.
Researchers have found numerous channels allowing methane to reach the seafloor, and discovered solid hydrate formations that can release gas as the ocean warms. This study aims to improve understanding of methane origins, escape routes, and potential impacts on global climate change.
Scientists at Centenary Institute discovered that liver cells can engulf and destroy T-cells, reducing organ rejection in transplants and potentially fighting hepatitis and other chronic liver diseases. The discovery opens up new approaches to transplant rejection and treatment of liver diseases, which affect millions worldwide.
A new study from the University of New Hampshire finds that overweight older women have less leg strength and power than normal-weight counterparts, which can lead to increased disability and loss of independence. The study suggests that maintaining a normal weight and improving strength through exercise may help mitigate this risk.
Biotech has added billions to farmers' incomes globally, with the four main crops of soybeans, corn, cotton, and canola experiencing significant increases. The study found that biotech benefits were particularly pronounced in developing countries, with GM insect-resistant cotton and herbicide-tolerant soybeans driving these gains.
A study by Cornell University researchers found that songbirds' ability to learn and remember songs is linked to the size and proportion of their brain regions. The research suggests that species with larger higher brain areas relative to lower areas can learn dozens or hundreds of different notes.
A study found that fast-evolving genes in social insects like fire ants and honeybees are responsible for their developmental differences. These genes exhibit elevated rates of evolution, even before they are recruited to produce diverse forms.
A team of researchers at UC Santa Barbara has developed a novel technique using laser spectroscopy and silver nanoparticles to discriminate between cancerous and non-cancerous cells. The technology can help identify unique tumor cells that may spread to other parts of the body, improving diagnosis and treatment outcomes.
Researchers at Case Western Reserve University are studying whether an over-the-counter medication, Glutamine, can ease chemotherapy side effects for people with blood and bone marrow cancers. The study aims to determine if Glutamine will interfere with chemotherapy or yield no benefits for patients diagnosed with multiple myeloma.
Researchers have developed new potato lines with genetic resistance to wireworms, a major pest that can cause significant damage to crops. The resistant clones outperformed insecticide-treated potatoes in field trials, suggesting that natural compounds like glycoalkaloids may be protecting the plants.
Researchers have discovered that squalamine, a compound isolated from sharks, demonstrates broad-spectrum antiviral activity against human pathogens, including dengue, yellow fever, and hepatitis B, C, and D. The study's findings suggest that squalamine could be explored as a novel human antiviral agent.
Based on current trends, only 31 developing countries are expected to achieve the under-5 mortality rate reduction goal by 2015, while 13 will reach the maternal mortality ratio goal. The study used crucial data sources not included in previous analyses.
A Phase I study is underway to test the safety and tolerability of a new androgen dimethandrolone undecanoate as a potential male contraceptive. Dr. Christina Wang hopes to develop an oral agent that can effectively decrease sperm production, offering men more frequent doctor visits and improved reproductive system understanding.
Researchers will integrate traffic flow and air quality monitoring using wireless computer networking to recommend alternate routes via on-board navigation devices. The technology aims to enhance existing solutions and close the loop between centralized management, navigators, and drivers.
Researchers have developed a technique to observe cystic fibrosis cellular intricacies, revealing the role of CFTR in regulating ENaC activity. The study found that healthy CFTR prevents ENaC overactivity, while defective CFTR allows it to occur.
A recent study published in Neurology found that people with diabetes are twice as likely to develop dementia as those with normal blood sugar levels. The study, which monitored over 1,000 participants for an average of 11 years, also found that controlling diabetes is crucial to prevent cognitive decline.
University of Pennsylvania researchers have developed a new technique for analyzing phylogenies, showing that the results stand up against known fossil history of whale species. The method allows for changing rates of speciation and extinction over time and among lineages.
NASA is testing an element of the sunshield that will protect the James Webb Space Telescope's mirrors and instruments during its mission. The sunshield will consist of five tennis court-sized layers to allow the telescope to cool to its cryogenic operating temperature.
A new study by Harvard Medical School researchers found that most uninsured patients in Massachusetts are employed but unable to afford employer-sponsored insurance or subsidized state plans. The study suggests that the system of coverage failed those who lost their job, particularly during economic downturns.
Routine depression screening for primary care patients has been deemed ineffective by researchers, with evidence suggesting it diverts resources away from those who need them most. Consistent treatment for recurrent depression is recommended as a more effective approach.
Researchers at Oregon State University found that increased species richness decreases the prevalence and severity of infection caused by the deadly chytrid fungus in amphibians. This study provides evidence for the importance of biodiversity in protecting ecosystem function and reducing disease transmission.
Using local biosurveillance data can improve diagnostic decisions and treatment for patients with communicable diseases. Researchers at Boston Children's Hospital found that incorporating real-time population-level data can help avoid unnecessary antibiotic treatment and correctly diagnose missed cases.
Experts analyze Fukushima's current and future impact, highlighting pressing government plans and challenging nuclear energy policies. The article also explores health impacts, media coverage, and the need for upgraded safety measures to prevent similar disasters.
Scientists warn that current climate model predictions are unreliable due to measurement uncertainties. A new satellite concept, TRUTHS, aims to improve accuracy by calibrating other satellites and facilitating the establishment of a global network with robust quality guarantees.
A new species of raptor dinosaur, Talos sampsoni, has been discovered in southern Utah, providing insights into the function of its enlarged talon and revealing a previously unknown level of feathered, bird-like characteristics. The study also sheds light on the behavior of theropod dinosaurs during the Late Cretaceous period.
Recent studies have shown that aldosterone antagonists reduce mortality and cardiovascular complications in patients with heart failure. The benefits of these drugs are clear, with a 24% reduction in cardiovascular death and a 42% reduction in hospitalization for heart failure.
Kansas researchers found that enriched infant formulas fortified with long chain polyunsaturated fatty acids (LCPUFA) are beneficial for developing brains and hearts. Infants fed these formulas showed improved cognitive advancement and lower heart rates compared to those without LCPUFA.
A preliminary study suggests that the SWIFT MRI technique can accurately detect mandibular invasion by squamous cell carcinoma, allowing for more precise planning and potentially preventing unnecessary removal of the jawbone. The researchers found a high degree of correlation between magnetic resonance images and histopathologic findings.
Researchers found that minority patients who develop adult leukemia die from it more often than white patients, with blacks having a 45% greater risk of death from ALL and Hispanics having a 46% greater risk. The study used the SEER database to examine statistics from 40,951 patients with acute leukemia over a 10-year period.
Research reveals that a high-salt diet and obesity trigger abnormal activation of the Rac1 protein in kidney cells, leading to increased blood pressure. This finding offers a potential new therapeutic target for treating salt-sensitive hypertension.
A new study found that neuroticism is linked to increased brain activity during pain anticipation in individuals with irritable bowel syndrome (IBS). This heightened emotional response may exacerbate chronic pain conditions. Physicians should consider a patient's mental state when determining treatment regimens.
Developed by Cardiff University, the test identifies a wound type based on its gene signature with an initial accuracy rate of 98%. It has the potential to transform service provision and provide the right treatment at the earliest possible opportunity.
Researchers discovered that mast cells release protein MCPT4, degrading Gila monster venom helodermin, reducing morbidity and mortality. This mechanism also applies to scorpion venom, providing a natural defense against deadly toxins.
Researchers have discovered a protein called ubiquitin ligase Nedd4L as a new regulator of cystic fibrosis. Mice lacking Nedd4L in the lung developed cystic fibrosis-like disease, highlighting a promising therapeutic target. Enhancing Nedd4L function or inhibiting ENaC may alleviate symptoms of the disease.
Researchers discovered proteins and genetic material from the 1918 influenza virus in specimens from 37 soldiers, including four who died between May and August 1918. The findings suggest that the virus did not undergo a dramatic change during the pandemic, contributing to unusually high mortality.
A new image-guided technique may enable more stroke patients to be successfully treated, particularly those living far from specialist medical care. Researchers found no difference in recovery time or 90-day survival rates between patients receiving treatment within six hours of symptom onset.
A new study provides clear evidence that many primitive bird species survived right up until the time of the Chicxulub meteorite impact. The team identified and dated a large collection of bird fossils representing various species, showing diversity in size, beak structure, and other features.
A study reveals that tumors can disable the T cell–attracting protein CCL2 by modifying it with reactive nitrogen species, keeping T cells out. Scientists are now developing RNS-blocking drugs to restore T cell function and potentially enhance cancer treatment.
A study published in mBio reveals that the 2009 H1N1 pandemic flu virus causes more extensive damage to lung tissues than seasonal flu, making it more susceptible to bacterial infections like pneumonia. This damage compromises the protective epithelial cells, allowing bacteria to thrive and increase mortality.
Researchers challenged online gamers to predict the structure of a protein-cutting enzyme from an AIDS-like virus using the game Foldit. The players successfully generated accurate models, which were refined and determined to be correct within days.
Researchers investigated 50-million-year-old clam shells and wood from Antarctica, finding a climate rhythm resembling El Niño and La Niña in the South Pacific Ocean. The results indicate that global warming may not disrupt the ENSO climate rhythm above the South Pacific Ocean.