The National Centre for HIV Epidemiology and Clinical Research has launched its new identity as the Kirby Institute, with a focus on broader work beyond HIV. The institute has received a $10m donation from The Atlantic Philanthropies to support new facilities and research.
Researchers have identified four new genes linked to Alzheimer's disease, adding to the existing understanding of its causes. The findings, published in Nature Genetics, provide key information for developing treatments and preventive measures.
Research studies presented at the ACC Meeting found associations between higher body mass index and increased cardiac risk factors, as well as a 47-percent reduction in radiation dose with lower kVp imaging. Additionally, persistence of left ventricular hypertrophy was linked to worse outcomes in patients with lower achieved systolic p...
Researchers found a potential target for treating squamous cell lung cancer by identifying a DDR2 gene mutation that responds to dasatinib treatment. Approximately one in two thousand people in the US annually carry this mutation, and tumor cells with it showed significant response to dasatinib, indicating a new targeted therapy option.
The RESOLUTE All Comers trial confirms that the new-generation Resolute zotarolimus-eluting stent is clinically equivalent to the Xience V everolimus-eluting stent after 2 years. The study included patients with complex lesions and acute coronary syndromes, demonstrating improved safety and efficacy of the zotarolimus-eluting stent.
Researchers at the University of Illinois have observed a nanoscale cooling effect in graphene transistors, which could enable devices to cool themselves and operate more efficiently. This self-cooling effect is stronger than resistive heating and has the potential to greatly improve energy efficiency.
Researchers have uncovered five new genes that increase the risk of developing Alzheimer's disease, adding to a total of ten identified genes. The study found that these genes are clustered in patterns, implicating immune system and cholesterol processing as risk factors.
Scientists at Brigham and Women's Hospital have developed nanoparticles containing calcium that can capture nickel efficiently without penetrating the skin. This breakthrough could provide a new strategy for preventing nickel-induced contact dermatitis, affecting millions worldwide.
Scientists have identified a new type of symmetry in materials, expanding possibilities for discovering materials with desired properties. This discovery can lead to the development of novel ferroelectric and ferromagnetic materials, which could be used in next-generation ultrasound devices and computers.
Researchers found that Hsp90, a common 'chaperone' protein, helps loose p53, contradicting its previous role in folding other proteins. This discovery adds to the growing knowledge of proteins' adaptability and activity in unfolded states.
A study found that young adult patients with hypertrophic cardiomyopathy survived cardiac arrest after receiving therapeutic hypothermia. The treatment was successful despite marked left ventricular wall thickness and other risk factors.
A regional prevention project involving 10,000 adults has shown a 24% reduction in acute heart attacks in a five-quarter period compared to the previous period of evaluation. The Heart of New Ulm Project combines environmental, peer leadership and individual interventions to prevent coronary heart disease.
Researchers identified four new genes, MS4A, CD2AP, CD33, and EPHA1, linked to Alzheimer's disease risk, adding to the understanding of the disease's causes. The findings may help determine who is at risk and aid in drug development.
A study found that guilt motivates cardiovascular patients to make lifestyle changes, particularly those with children. Providers are advised to address guilt in routine care to improve patient outcomes. The study involved 100 adult cardiology outpatients and revealed that nearly two-thirds had experienced a major cardiovascular event.
A multidisciplinary team identified digoxin as a possible therapy for prostate cancer through drug repositioning. Regular digoxin use reduced the risk of prostate cancer by 24% and 46% for long-term users, respectively.
A recent study by the Society for Healthcare Epidemiology of America found a dramatic increase in the use of carbapenems, powerful last-resort antibiotics, over five years. This trend is alarming as carbapenem-resistant bacteria become more common, weakening their effectiveness against emerging infections.
A new drug that targets a signaling-nuclear protein pathway has been shown to prevent heterotopic ossification, a painful buildup of bone tissue. The study's results offer great hope for the development of effective medications to treat this debilitating disease.
Researchers have identified an oncogenic gene fusion of KRAS in a metastatic prostate cancer cell line, shedding light on the genetic characteristics of this disease. This finding may enable better prognostic information to separate slow-growing tumors from aggressive ones, ultimately improving treatment strategies.
Researchers have found alarming rates of antibiotic use and the emergence of multi-drug resistant bacteria, including carbapenem-resistant Klebsiella pneumonia. Electronic faucets are also more likely to become contaminated with bacteria compared to traditional faucets.
Research from the Emory/Georgia Tech Predictive Health Institute found that vitamin D deficiency is associated with stiffer arteries and impaired blood vessel function. Participants who increased their vitamin D levels showed improvements in vascular health and lower blood pressure.
A recent study published in the American Association for Cancer Research found that smoking did not affect breast cancer risk among obese postmenopausal women. In contrast, non-obese women with a history of smoking had a significantly higher risk for breast cancer.
Researchers at Hebrew University have successfully doped semiconductor nanocrystals with impurity atoms, improving their electrical conductivity. This breakthrough could lead to the development of new electronic products, including nanolasers, solar cells, and sensors.
A study by NIH-funded researchers has found that boosting adult neurogenesis in the hippocampus improves pattern recognition abilities, similar to those seen in younger brains. However, combining this with exercise was necessary for antidepressant-like effects to emerge.
Researchers found that individuals with metabolic syndrome are at higher risk for developing liver cancers, including hepatocellular carcinoma and intrahepatic cholangiocarcinoma. The study, presented at the AACR 102nd Annual Meeting, highlights the importance of metabolic syndrome in increasing liver cancer incidence.
A large-scale study identified four new genes linked to Alzheimer's disease, adding to the existing pool of genes that contribute to the risk. The findings provide valuable insights into the disease's underlying mechanisms and may lead to the development of more effective treatments and preventive measures.
A study found that young African-American competitive athletes with sickle cell trait are at risk of sudden death, particularly during football training. The study suggests that pre-participation screening is crucial to identify and prevent such deaths.
Researchers found that men using digoxin had a 24% lower risk of prostate cancer. The study also identified other approved drugs with anti-prostate cancer properties, paving the way for further research and potential new treatments.
A study found that diabetes is associated with a lower risk of prostate cancer in men, but a higher risk of other cancers and mortality in both men and women. Diabetes was linked to increased risks for colon, rectal, and liver cancers in men and women.
A consortium of researchers has identified four new genes associated with an increased risk of developing Alzheimer's disease. The study analyzed over 54,000 individuals and found that these genes contribute to the disease by disrupting brain biochemistry. Understanding the role of these genes could lead to the development of new treat...
A UCSF research team has made a breakthrough in predicting breast cancer survival by analyzing the immune profile of tumors. By identifying specific patterns of immune cells, they were able to develop a treatment strategy that slows tumor growth and improves patient outcomes.
Materials scientists at Harvard have successfully demonstrated the first macro-scale thin-film solid-oxide fuel cell, overcoming structural challenges to achieve comparable power density to micro-SOFCs. The breakthrough uses a metallic grid to support a large membrane, enabling scalability for practical clean-energy applications.
A recent study published in the American College of Cardiology's annual scientific sessions reveals that routine periodic fasting can lower one's risk of coronary artery disease and diabetes. Fasting was also found to reduce other cardiac risk factors, such as triglycerides, weight, and blood sugar levels.
Researchers at Columbia University have developed a new way to stimulate neuron production in the adult mouse brain, improving cognitive functions. The study suggests that stimulating neurogenesis may contribute to treatment of anxiety disorders, including PTSD and panic disorder, by enhancing pattern separation.
A new study found that young women with breast cancer have limited knowledge about fertility issues, causing confusion and conflict when planning for a family. The researchers suggest providing targeted fertility information may reduce uncertainty and increase informed decision-making.
Researchers found that macrophage and T-cell levels can predict recurrence and survival in breast cancer. A new therapy targeting macrophages shows promising results in preclinical studies.