Scientists at St. Jude Children's Research Hospital have developed a new algorithm called CREST to identify chromosomal aberrations in tumors, which are likely to advance our understanding of cancer. Using CREST, researchers found 89 new structural differences in cancer genomes and 50 new variations in melanoma cells.
Researchers discovered that on average, thirty mutations are transmitted from each parent to their child, revising previous estimations and revolutionizing the timescale used to calculate generations separating humans from other species. This finding has important implications for research tying specific genetic mutations to diseases.
A study found that ambulance diversion, a practice to reduce overcrowding, may increase mortality for patients with acute myocardial infarction. Patients exposed to 12 or more hours of diversion had higher mortality rates at 30-day, 90-day, 9-month, and 1-year follow-ups.
A survey of European and US anaesthesiologists found that only 35% monitor cardiac output during high-risk surgery, leading to postoperative complications. The authors call for increased awareness and implementation of guidelines for cardiac output monitoring.
A recent study published in JAMA found that bariatric surgery among older, severely obese patients is not associated with reduced mortality. The study examined the long-term survival of high-risk patients who underwent bariatric surgery and compared them to nonsurgical controls.
Researchers found that humans receive approximately 60 new mutations from their parents, with varying rates coming from the mother and father. The study provides a direct measure of new mutations and reveals surprising differences in mutation rates between families.
Researchers at UCL have demonstrated the first electrically driven quantum dot laser grown directly on a silicon substrate with a suitable wavelength for telecommunications. This breakthrough enables efficient light sources in silicon, a crucial material for future silicon photonics.
A new study using satellite observations and high-resolution images found that brief changes in soil moisture can affect storm generation in the Sahel region of West Africa. This could lead to improved predictive modeling for crops, which are crucial for the people affected by droughts in the area.
A new study links heart attack death rates to ambulance diversion, revealing that overtaxed emergency rooms lead to worse patient outcomes. For every 100 patients with acute myocardial infarction, there are three potentially avoidable deaths when ambulances are diverted for long periods.
Researchers at Massachusetts General Hospital developed a living laser device using a single GFP-expressing cell, which can produce hundreds of pulses of laser light. The cellular device refocuses the light and induces emission of laser light at lower energy levels than required for solution-based devices.