Add BrightSurf on Google Email

Science News for March 20, 2011


New data published in Nature Genetics demonstrate that tiny LNA-based compounds developed by Santaris Pharma A/S inhibit entire disease-associated microRNA families

Tiny LNA-based compounds developed by Santaris Pharma A/S successfully inhibit entire microRNA families, targeting cancer, viral infections, and cardiovascular diseases. The high affinity and target specificity of these compounds enable functional inhibition without off-target effects.

SourceEdelman PR·JournalNature Genetics·DateMar 20, 2011

Climate change hits home

A new study by Cardiff University and Ipsos-MORI found that direct experience of extreme weather events like flooding can significantly affect people's perceptions of climate change. As a result, individuals who have experienced flooding are more prepared to take personal action and reduce their energy use.

SourceCardiff University·JournalNature Climate Change·DateMar 20, 2011

Mutant prions help cells foil harmful protein misfolding

Researchers at Brown University have discovered that mutant prions can aid cells in overcoming harmful protein misfolding, a process thought to be catastrophic. The findings suggest that targeted interventions at various stages of the misfolding process can enable cells to overcome the problem.

SourceBrown University·JournalNature Structural & Molecular Biology·DateMar 20, 2011

Preventive antibiotic use significantly lowers risk of infection with antibiotic-resistant bacteria in intensive care patients

A large randomized trial found that preventive antibiotic use significantly reduces the risk of infection with highly resistant microorganisms in intensive care patients. Patients treated with selective digestive tract decontamination (SDD) were 59% less likely to develop bacteraemia and 38% less likely to colonize respiratory tracts.

SourceThe Lancet_DELETED·JournalThe Lancet Infectious Diseases·DateMar 20, 2011