A study found that varenicline (Chantix) is associated with a substantially increased risk of reported depression or suicidal behavior compared to other smoking-cessation treatments. The researchers identified 90% of all reported suicides related to smoking cessation drugs since 1998 implicated varenicline.
Researchers at Mayo Clinic found that eliminating senescent cells can prevent or delay the onset of age-related disorders and disabilities. The study showed that lifelong elimination of these cells delayed age-related disorders such as cataracts and muscle loss, and slowed their progression in already established diseases.
Cardiovascular Magnetic Resonance (CMR) has become a critical diagnostic tool in clinical cardiology, providing comprehensive assessments of ventricular function, cardiac morphology, perfusion, viability, and metabolism. CMR offers significant advantages over other imaging modalities, including the absence of ionizing radiation and hig...
A study by Michigan State University found that video game playing boosts creativity in tasks like drawing and writing, but not other technology use. The researchers surveyed nearly 500 middle-school students and used the Torrance Test of Creativity-Figural to gauge their creative abilities.
The University of Pittsburgh's Department of Computer Science has been awarded a CUDA Teaching Center by NVIDIA. The award includes $25,000 worth of graphics processing units, a teaching assistant, textbooks, software licenses, and remote testing access.
A study published in Environmental Health Perspectives found that replacing short auto trips with bicycle trips can save an estimated $7 billion per year by reducing mortality and healthcare costs. Biking also improves local air quality and reduces greenhouse gas emissions.
Graphene's unique properties, including fast electron mobility and high mechanical strength, make it suitable for fast analog electronics. Researchers are working to improve synthetic graphene quality and study its behavior in technology conditions.
Eating mixed nuts daily boosts serotonin levels in MetS patients, decreasing hunger and improving heart health. A 12-week nut-enriched diet showed significant biochemical effects, including reduced inflammation and cardiovascular risk factors.
Researchers find that toxic byproducts from unsaturated fat breakdown lead to severe inflammation, cell death, and multi-system organ failure in obese acute pancreatitis patients. The study provides new insight into how fat can induce complications after sudden inflammatory illnesses.
A Stanford study found that nitroglycerin's continuous use can lead to increased heart attack severity in rats. Treatment with Alda-1 enzyme activator reduced the detrimental effects of prolonged nitroglycerin use.
Researchers discovered signals within exons 9 and 10 of the PK-M gene that determine mutually exclusive splicing, promoting PK-M2 production in cancer cells. This finding has implications for developing therapies to reverse the Warburg effect.
The study shows that ivacaftor significantly improves lung function, reduces sweat chloride levels and decreases respiratory distress symptoms in CF patients with the G551D mutation. This is a promising treatment option for approximately four percent of CF patients worldwide.
Researchers at Ohio State University Medical Center have developed a viral vector designed to deliver a gene into the eyes of people born with an inherited form of blindness. The trial aims to treat choroideremia, a disease affecting 100,000 worldwide, and holds promise for other genetic causes of blindness like retinitis pigmentosa.
A new study by Rhode Island Hospital reports that web-based assessments for outcome measurements of patients in treatment for depression are valid and reliable. The researchers also found that patients preferred the Internet version over the paper version, citing it as less burdensome, time-consuming, secure, and accurate.
A potential EBV vaccine could prevent infectious mononucleosis and cancers linked to the virus. Researchers prioritize studying immune responses to vaccination and identifying biological markers for cancer prediction.
A recent study suggests that increasing air pollution in the Indian sub-continent is intensifying tropical cyclones in the Arabian Sea. The weakening of wind-shear patterns over the sea allows stronger storm development, resulting in more intense storms.
A new study reveals that the diversity of organisms living on coral reefs is much greater than previously thought, with 525 species of crustaceans found in a small sample area. This underestimation highlights the need for further research and conservation efforts to protect these endangered habitats.
Food processors face challenges in reproducing textures with reduced ingredients, but natural alternatives like plant-based compounds and natural emulsifiers help. The American Chemical Society explores the science behind creating 'light' or '-free' versions of products.
A recent study reveals that neither human activity nor climate change alone caused the Ice Age megafauna extinctions. However, the research suggests that a combination of factors, including humans and climate change, contributed to the loss of large mammal species in Eurasia and North America.
Researchers created a novel 3D long-term bone marrow culture system to investigate stromal cell biological function. This system successfully maintained hematopoietic stem cells (HSCs) for extended periods, enabling the analysis of stromal-cell interactions and regulatory factors.
Researchers at University of Copenhagen found that children born vaginally with diverse gut bacteria have lower risk of allergies. The study suggests that early exposure to a variety of bacteria is crucial for a healthy immune system, contradicting the long-held notion that bacteria are a threat to public health.
Researchers at Argonne National Laboratories and Penn State have developed a new solar concentrator design that improves light collection efficiency. The new design achieves near-lossless propagation for several different chromophores, enabling a more than twofold increase in concentration ratio compared to conventional LSCs.
A Tel Aviv University-developed technology uses a hyperspectral camera to analyze the world we live in, detecting contaminants and environmental hazards in real time. The sensor can provide immediate, cost-effective, and accurate monitoring of forests, urban areas, agricultural lands, harbors, or marinas.
A UT study reveals climate change affects ants' ability to disperse seeds and perform vital ecosystem functions, potentially jeopardizing plant biodiversity. Researchers observed dramatic changes in ant behavior in response to temperature increases.
Researchers have discovered a key trigger for producing normal red blood cells that could lead to a new treatment for those with sickle cell disease. Increasing the expression of proteins TR2 and TR4 more than doubled the level of fetal hemoglobin produced in sickle cell mice, reducing organ damage.
Researchers discovered that a widely used bee antibiotic increases susceptibility to pesticides, contributing to colony collapse disorder. The study suggests that oxytetracycline interacts with specific proteins in the bees, rendering them more vulnerable to toxic chemicals.
Air pollution linked to stronger cyclones in Arabian Sea, with research suggesting aerosol buildup over India deflects sunlight, creating dimming that enables stronger storms. Scientists note a trend of increasingly strong cyclones in months preceding monsoon season.
Separating newborns from their mothers stresses the baby, with heart rate variability increasing by 176% and quiet sleep decreasing by 86%. Skin-to-skin contact with mother reduces this stress, but further research is needed to understand its long-term effects.
Researchers developed a new method using two-photon polymerization with multiple foci to create finely detailed structures, such as tissue scaffolds and microneedles, more quickly than traditional techniques. This enables faster production of microscale medical devices for tissue engineering applications.
A collaborative research partnership between Institut Pasteur Korea and Sanofi aims to combat Hepatitis B by developing a high-throughput assay to screen chemical libraries for novel compounds. The goal is to identify inhibitors targeting specific steps in the viral life cycle, offering new insights into HBV mechanisms.
New study reveals two young galaxies at 12 billion years old with super-solar metal abundances, challenging our understanding of the universe's chemical evolution. The findings support the idea that gamma-ray bursts are associated with vigorous massive star formation and provide insights into the history of the early universe.
A University at Buffalo study found exenatide to have a rapid and powerful anti-inflammatory effect, which occurred independently of weight loss in obese type 2 diabetics. The drug also showed a significant drop in average blood sugar levels over three months.
Scientists studying drugs for dementia treatment also find promise in treating heart failure, driven by a common enzyme. Preliminary studies suggest that blocking this enzyme may help slow the progression of both conditions.
Men with locally advanced or high-risk prostate cancer who receive combined radiation and hormone therapy live longer and are less likely to die from their disease. The treatment improved overall survival by 23% and disease-specific survival by 43% compared to hormone therapy alone.
Researchers found that the measles virus uses a protein called nectin-4 to infect and leave from the throat, making it highly contagious. This discovery may also help in fighting ovarian, breast, and lung cancers.
A workshop titled 'Act your Age! Challenging Stereotypes' brings together young children and older adults to explore perceptions of ageing. Through interactive activities, participants develop self-awareness and intergenerational relationships, challenging negative views of older people.
Researchers are exploring ways to enhance farm profitability by extending the grazing season and adding value to milk through flaxseed supplementation, addressing concerns of organic dairy farmers in the Northeast. The project also aims to improve milk quality by sustaining omega-3 fatty acids and CLA concentrations throughout the year.
A new software system called Peregrine has been developed to improve the reliability and security of multithreaded programs. It uses a deterministic approach to prevent data races and bugs, making it faster than previous systems while not requiring new hardware or languages.
Researchers found that boosting a gene in fruit flies' intestinal stem cells extended their lifespan by up to 50% and delayed the aging of their intestine. The study suggests that the gene, PGC-1, can act as a biological dial for slowing the aging process and may serve as a target for new therapies.
A new study found that peatlands will continue to sequester their huge deposits of carbon and methane under moderate climate change conditions. The research used laboratory simulations to study the decomposition of wet bog peat, showing that carbon release slows down in deeply buried peat.
A study published in BMJ Open found that if the UK population adopted the average English diet, around 4,000 deaths could be prevented every year. The research suggests that a poor diet high in saturated fats and salt contributes to higher death rates in Scotland, Wales, and Northern Ireland compared to England.
A fossil fragment from Kent's Cavern in southern England establishes the presence of modern humans in western Europe by 40,000 years ago. The discovery joins a human skull and lower jaw from Romania, confirming modern humans at both ends of Europe by this date.
A new treatment for severe hemophilia A patients with inhibitors has been shown to be highly effective in preventing bleeding events. The study, published in the New England Journal of Medicine, found that FEIBA infused three times a week resulted in a 62% reduction in all bleeding events and a 72% reduction in target joint bleeding.
The University of Maryland Center for Integrative Environmental Research finds that Maryland's Climate Action Plan improves electric reliability while having a negligible impact on manufacturers. The plan is expected to generate new business opportunities and jobs in the green sector, with potential growth in employment opportunities.
A new study by Rutgers neuroscientist Bonnie Firestein suggests that increased production of protein cypin may prevent long-term brain damage after a stroke. Cypin helps nerve cells survive, while excessive PSD-95 accelerates cell destruction and inhibits recovery.
A new study by UCLA researchers shows that a specialized mental health intervention for suicidal youth can significantly improve follow-up treatment rates. The intervention, which involves a family-based crisis-therapy session and telephone support, resulted in higher rates of follow-up treatment compared to standard ED treatment.
A new study using genetic, archeological, and climatic data found that humans and climate fluctuations contributed to the extinction of six large Ice-Age mammals. The research suggests that as the Earth warmed after the last ice age, these species were unable to find alternative habitats, leading to their demise.
TRMM Satellite tracks Tropical Storm Keila's formation in the Arabian Sea, showing moderate to heavy rainfall spiraling into its center. The storm made landfall in Oman and is expected to track west-southwest along the coastlines of Oman and Yemen.
Researchers have confirmed a rare incidence of individuals becoming infected with both seasonal and pandemic strains of the flu at the same time. Experts say this highlights the ongoing risk of distinct flu viruses combining in human hosts, particularly in Southeast Asia where avian influenza and pandemic H1N1 are prevalent.
Antibodies have been found to trick certain bacteria into killing each other, providing a new mechanism for bacterial clearance. Additionally, researchers suggest that humoral immunity may play a role in eliminating old seasonal influenza virus strains by inducing an anti-stalk antibody response.
Studies explore Ligurian accretionary complex evolution and Andean thrusting, shedding light on continental margin dynamics. Cosmogenic isotope analysis reveals insights into the geological history of Wonderwerk Cave and Redoubt Volcano.
Researchers found that administering a diabetes drug to newborn animals prevents the development of diabetes in adulthood. The study suggests an important developmental window for intervention to protect insulin-producing cells.
Researchers discovered a crucial brain area, neuro-hypophysis, where biochemical commands are passed from the brain to the bloodstream. They found that oxytocin, known as the 'hormone of love,' plays a key role in the development of this structure, governing blood vessel formation during embryonic stages.
USC Associate Professor Ellis Meng is selected for the NSF's Innovation Corps award to develop and commercialize her tiny, implantable medication-delivery system. The system has a better volume efficiency, allowing it to be powered wirelessly and used in animal studies.
A new MU study reveals that depression affects breast cancer survivors, with single women and mothers experiencing higher rates of distress. The research also shows that depressed patients are less likely to adhere to medication regimens, potentially complicating treatment outcomes.
A pivotal Phase 3 clinical trial found that ivacaftor provides sustained improvement in lung function, growth, and other signs and symptoms for cystic fibrosis patients. The therapy targets the underlying cause of CF, restoring balance on airway surfaces.
A recent Rhode Island Hospital study found no statistically significant difference in adolescent marijuana use between Rhode Island and Massachusetts after the state's medical marijuana legalization in 2006. The study of over 32,570 students from 1997 to 2009 suggests that concerns about increased youth use may be unfounded.
A study published in PLOS ONE reveals that big cats' square-shaped vocal cords allow for louder roars at lower lung pressure, making it easier for the tissue to respond to airflow. This discovery contradicts a long-held theory and could potentially help doctors reconstruct damaged vocal fold tissue.
Researchers find tau proteins interact with negatively charged lipids on cell membranes, causing protein aggregation and neuronal death. Compounds that prevent protein interaction with membranes offer hope for Alzheimer's patients.
Researchers at Northwestern University developed a new material that absorbs a wide range of wavelengths, enabling more efficient solar cells. The innovative trapezoid shape could be replicated in semiconducting materials to lead to thinner, lower-cost, and more efficient solar technology.