David A. Estell, a Genencor researcher, received the Enzyme Engineering Award for his work on protein engineering and developing efficient proprietary technology for producing advanced biofuels. He has also initiated new technology development and holds over 70 issued U.S. patents.
A University of Cincinnati study found that shoppers base quality inferences on signs, ranking signage as the most useful source for new product information. Signs tie with magazine ads as the second most useful, while outdoor and radio ads rank lower.
A study by UCLA researchers found that primary care physicians who treat Latino patients are less likely to believe they can provide high-quality care. The challenges include inadequate time with patients, lack of affordability, non-adherence to treatments, and difficulties in communication. Implementing the Affordable Care Act may add...
Three randomized trials found that structured behavioral programs were more effective than control interventions in improving glycemic control among adults with long-duration poorly controlled diabetes. Individual education also showed better glucose control results compared to group education.
A British engineering team is embarking on a scientific mission to collect water and sediment samples from a subglacial lake in Antarctica. The 'deep-field' research mission aims to find new forms of microbial life and provide clues about the Earth's past climate, with potential implications for understanding the evolution of life on o...
A new study has found that zoledronic acid can prevent and treat bone loss in postmenopausal breast cancer patients taking aromatase inhibitors. The five-year study showed significant increases in bone density when the drug was administered upfront, but also found that initiating treatment even after bone loss developed was beneficial.
Researchers have developed a method to create tolerance in the immune system by attaching peanut proteins onto blood cells and reintroducing them. This approach has shown promise in preventing life-threatening allergic reactions. By tricking the immune system, researchers hope to target multiple food allergies at once.
Researchers discovered high-functioning individuals with autism do not consider others' thoughts when making decisions. This finding provides insight into the psychology of autism-spectrum disorders and has implications for therapies and public education.
Researchers at Georgia Tech discovered that a strong electric field can induce solidification in liquid droplets of formamide, forming crystallites. The study used molecular dynamics simulations to track the evolution of materials systems and found that increasing the field strength led to shape transitions and eventually solidification.
The University of Colorado Denver has been awarded a $750,000 grant by the National Science Foundation to investigate sustainable cities. The four-year project will bring together researchers from 20 US universities and international partners to reduce energy use, carbon emissions, and mitigate climate risks in urban areas.
A Kaiser Permanente study found that antidepressants, diuretics, bronchodilators, antihistamines, and sympathomimetics can cause lower urinary tract symptoms (LUTS) in men. The study examined data from over 63,000 ethnically diverse men and found associations between specific medication classes and LUTS severity.
The new institute will advance revolutionary materials research and education, focusing on nanomaterials and energy-efficient technology. UCSB will educate future scientists and engineers through corporate internships and a $2 million endowment.
Scientists at UC Metabolic Diseases Institute discover that targeted inhibition of CB1 receptor can increase calorie burning in brown adipose tissue, leading to reduced body weight and blood glucose. Further study aims to find a safer and more effective drug strategy for glucose regulation and weight loss.
Researchers have discovered a remarkable fossil site in Nevada where the remains of nine 45-foot-long ichthyosaurs suggest an even larger and more cunning sea monster existed: a Triassic kraken. The evidence implies that this ancient cephalopod was capable of intelligent manipulation of bones and preyed on these massive reptiles.
Popular herbal supplements like feverfew, ginger, and St. John's Wort can interact with prescription medicines, posing serious side effects when combined during and after surgery. Discontinuing use at least one to two weeks prior to surgery can help avoid adverse events.
Early humans' immune system responded strongly to Neu5Gc, a sugar molecule found on most animal cells. This response likely reduced reproductive success in males with high levels of Neu5Gc, driving the evolution of human ancestors.
Researchers from Arizona State University developed a new geochemical technique to study the Earth's largest mass extinction event. The study found that the period of oceanic anoxia was much shorter than previously estimated, occurring at most tens of thousands of years before the extinction event.
A new study reveals that antivirulence drugs can suppress resistance in pathogens by targeting social interactions and cooperation. Laboratory simulations showed that resistant strains will not overtake sensitive strains when therapies target cell-to-cell communication, allowing antivirulence therapies to work even when resistance arises.
A team of researchers has identified Sirt1 as a crucial protein linking caloric restriction to improved insulin action in skeletal muscle. This finding provides new targets for therapeutics to reduce insulin resistance and lower the risk of developing type 2 diabetes.
A Mayo Clinic study recommends adding categories to more effectively identify and treat people with preclinical Alzheimer's disease, a long latent stage of the disease. The researchers suggest two additional sub-groups: Stage 0 (normal biomarkers and no cognitive impairment) and SNAP patients (with suspected non-AD pathophysiology).
Research by biologists at the University of York has revealed that under stressful conditions, synapses can grow excessively, potentially contributing to dysfunction. This finding has strong implications for neuronal function as brains age and adds significantly to our understanding of neurodegenerative diseases.
Researchers found that US patients started dialysis approximately five months earlier on average between 1997 and 2007. This delay reduction translates into additional hemodialysis treatments, hours of treatment, and payments for each patient.
Researchers at the University of Gothenburg have discovered a modified aquaporin, AQP10, which is more stable due to its carbohydrate structure. This stability makes it potentially useful for treating diseases such as eczema and cancer.
Researchers at UC Berkeley found that ending the hybrid car program in California's carpool lanes slowed traffic for all drivers, not just hybrids. The study showed that moving hybrids out of carpool lanes increased congestion in adjacent lanes and reduced overall traffic speed.
Researchers identified a potential combination therapy to effectively use receptor tyrosine kinases inhibitors for KRAS mutant colorectal cancers by combining with MEK/ERK signaling pathway inhibitors. This approach could offer new treatment options for individuals with KRAS mutant cancers.
Children tend to dislike peers with undesirable characteristics more if they attribute fault for the trait rather than assuming they've tried to change it. However, when a peer has attempted to overcome an issue, kids are more accepting and even positive towards them.
Researchers at Oregon State University have developed a new computer program that enables highway construction engineers to analyze soil movements caused by active landslides and erosion in real-time. This technology uses LIDAR to better assess and deal with these issues, ultimately improving construction quality and safety.
Researchers at the University of Manchester have created a graphene 'Big Mac' structure that isolates graphene from environmental influences, allowing for better electronic properties. This breakthrough enables the potential replacement of silicon chips in computers with graphene-based transistors.
Researchers at Massachusetts General Hospital have developed a novel technique using RNA interference to block inflammation in animal models of several disorders. The technique targets specific inflammatory cells that contribute to conditions such as heart disease and cancer, reducing damage and improving survival rates.
Researchers at Harvard University have successfully controlled the rate of photon emission from luminescent imperfections in diamond, a crucial step towards developing scalable quantum networks. The breakthrough uses nitrogen-vacancy centers in diamond to emit red photons at room temperature.
Academics say a study used to justify patient choice in the NHS is fundamentally flawed and misleading. The report highlights errors in the original study and concludes that it does not prove cause or effect between patient choice and death rates.
Genome-wide studies have identified new genes involved in melanoma susceptibility, including Caspase 8 and ATM gene. The study validates regions and genes already identified as significant for melanoma, reinforcing the role of cell cycle genes like CDKN2A and CDK4.
Researchers identified a mechanism for regulating color vision by studying the fly's visual system, showing that Rhodopsins can prevent incorrect gene expression and maintain color discrimination. The findings also offer insights into how genes controlling color detection are turned on and off.
Researchers have discovered a small molecule, microRNA-101, that can block autophagy in cancer cells, making them more sensitive to treatment with the anti-hormone Tamoxifen. This breakthrough has significant clinical relevance for treating breast cancer.
Professor Hilton's receipt of the award recognises his research into how cytokines signal between cells, including the discovery of many molecules involved in this process. He has made significant contributions to our understanding of cytokine biology and its applications in cancer, infectious diseases, and autoimmune conditions.
Healthcare access in Greece declined during the financial crisis, with long waiting times and supply-side problems contributing to reduced doctor consultations. This led to increased hospital admissions, suicides, and other alarming indicators such as rising HIV infections and heroin use.
Researchers have discovered gamma rays with unprecedented energies from the Crab Pulsar in the Crab Nebula, contradicting existing theories. The findings suggest a different mechanism for producing these high-energy particles, which could be detected by the VERITAS observatory.
A University of Wisconsin-Madison study suggests that short-term sleep restriction in adolescent mice prevented balanced growth and depletion of brain synapses, which may have lasting consequences for the wiring of the brain. The study's findings could be relevant to mental illnesses like schizophrenia that often start during adolescence.
Researchers at the University of Illinois at Chicago have created a biosensor to measure membrane lipid levels, which can act as switches turning on or off protein-protein interactions. This technique allows for real-time quantification and monitoring of lipid molecules, potentially leading to new pathways for disease treatment.
Researchers discovered three new DNA faults linked to melanoma, which are not related to hair, skin, or eye color. The genes, MX2, ATM, and CASP8, increase the risk of developing melanoma by 30 percent, particularly in people with two copies of these gene faults.
A UA-led team of researchers discovered a new edge in overcoming resistance to certain pests by modifying the structure of crop-protecting proteins called Bt toxins. The modified toxins were found to be effective against some resistant strains, but not always working as expected and requiring further testing.
Over the past decade, antiretroviral therapy has effectively managed HIV in adults with virological failure to all three original drug classes. Since 2000, nearly one in five patients achieved undetectable viral loads after treatment failure, increasing to nearly three in five by 2009.
A recent study published in Nature Cell Biology has discovered that bookmarking genes before cell division accelerates their reactivation afterwards. By analyzing the kinetics of gene activation, researchers found that a histone molecule undergoes chemical modification and is preserved during mitosis, allowing for rapid reactivation.
Research shows that optimistic individuals tend to filter out negative information, updating their estimates only when the new data is better than expected. This faulty frontal lobe function can lead to unrealistic predictions and a lack of caution, with potential downsides for mental health and decision-making.
A study found that individual differences in response to caffeine may predict how people respond to other stimulant drugs, including amphetamine and cocaine. Caffeine 'Choosers' reported more positive effects of d-amphetamine compared to 'Nonchoosers'.
A new report highlights significant disparities in health care access and outcomes among vulnerable populations. The Commonwealth Fund Commission recommends a three-pronged policy framework to ensure adequate access, financial protection, and improved coordination of care. This will help reduce rates of preventable hospital admissions ...
Researchers analyzed SEC23B gene mutations in CDA II patients and found that two variants, R14W and E109K, are more common in Italian population. The R14W variant is believed to have originated 3,000 years ago in Southern Italy, while E109K may have originated in the Middle East around 2,400 years ago.
Scientists investigate whether diesel nanoparticles are affecting bees' brains, causing them to lose their way back to the hive. The study aims to understand how tiny particles in diesel fumes could be contributing to bee colony collapse, which has economic and ecological implications for global pollination.
Researchers found that X chromosomes with fewer rDNA genes are more likely to be lost during male determination, leading to non-mendelian inheritance. This suggests a biased transmission of sex chromosomes in aphids.
The UCSF MRI technology center has been awarded a $5.5 million NIH grant to advance new magnetic resonance imaging (MRI) technology that can detect cancer's aggressiveness more accurately. The technique, tested in a small pilot study, uses a new instrument to boost the MRI signal and measure enzyme activity in real time.
Researchers at Stanford University used remote wildlife cameras to confirm mountain lion activity in the preserve, with seasonal patterns and human-lion encounters explored. The study suggests that mountain lions are present about 24% of the time, posing a low risk to humans.
A new study from CAMH found a specific gene linked to suicidal behaviour, particularly in those with the methionine variation of the gene
Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, and psoriasis. Understanding this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases.
A new study suggests that short-hard interstellar radiation events could have a significant impact on life on Earth, depleting the ozone layer and allowing deadly ultraviolet radiation to penetrate. The rate of these events is estimated to be about once per 100 million years, with potential effects on extinctions in the fossil record.
The University of Massachusetts Amherst has been chosen to lead a consortium of seven universities in hosting the Northeast Climate Science Center, a five-year, $7.5 million grant. The center will study climate change effects on ecosystems, wildlife, and resources in the region.
The study found that archaeophytes, introduced since Neolithic agriculture, are positively affected by arable land availability at low altitudinal ranges. Invasive neophyte species harbor 67% of Prague's nature reserves, including many shrubs and trees with high invasion potential.
A University of North Carolina at Chapel Hill researcher is leading a collaborative network to study the genetic determinants of Barrett's esophagus and esophageal adenocarcinoma. The network aims to develop new methods for identifying individuals at risk, early detection, and monitoring Barrett's esophagus progression.
A new survey suggests that many Type Ia supernovae result from the merger of two white dwarf stars, challenging previous theories about their origins. The study, which analyzed data from distant exploding stars, found that these events may be more common than previously thought and could provide insights into the history of the universe.
A new study found that babies at 15 months old can distinguish between fair and unfair food distribution, with those showing a greater willingness to share displaying increased sensitivity to such violations. This suggests that early childhood is an essential period for nurturing human egalitarianism and cooperation.
Christoph Lepper, a Carnegie staff associate, received the NIH Director's Early Independence Award for his groundbreaking research on skeletal muscle biology. The award aims to launch talented young scientists into independent positions directly out of graduate school.