A new map created by Japanese researchers helps identify high-rise buildings in the Osaka Basin vulnerable to long-period strong ground motions that last minutes. The map provides useful information for engineers to design earthquake-resistant buildings.
Researchers at UCLA's Pediatric Medical Home will study ways to reduce preventable hospital admissions and emergency room use among children with medically complex illness, aiming to decrease healthcare expenditures. The study will analyze root causes of preventable hospitalizations and design cost-saving strategies.
Researchers at Columbia University and Georgia Institute of Technology found that certain volatile organic gases can enhance aerosol activity, promoting cloud droplet formation. This discovery will improve climate modeling by incorporating gas-phase surfactants into cloud formation models.
Cyclone Felleng formed over the Mozambique Channel and transitioned into a cold core low pressure area, with NASA's TRMM satellite capturing its rainfall rates. The storm dissipated in the next couple of days as it moved south-southeast in the open waters of the Southern Indian Ocean.
A new study from McGill University reveals that the DCC receptor is essential for normal synaptic function and plasticity, leading to progressive degeneration of synapses and defects in memory formation. The absence of DCC leads to memory loss similar to Dr. Brenda Milner's famous subject HM.
Researchers at Stanford University School of Medicine have discovered an antibody that can inhibit the growth of gastrointestinal stromal tumor (GIST) cells resistant to other treatments. The antibody targets KIT receptor mutations, stimulating immune cells to kill rogue cells.
A new TB vaccine, MVA85A, did not offer extra protection against TB in South African infants who had already received the BCG vaccine. The vaccine induced modest immune responses, but these were insufficient to protect against the disease. Further research is needed to understand why this was the case.
Climate change affects human health, prompting physicians to take action; doctors can lobby governments, reduce greenhouse gas emissions and clinical waste. Immediate wise action is necessary to mitigate disastrous consequences.
Researchers have identified multiple brain regions responsible for generating fear and panic, including the amygdala, brainstem, diencephalon, and insular cortex. The findings suggest that an intact amygdala normally inhibits panic, and its absence can lead to anxiety-related conditions.
Researchers have identified plasmacytoid dendritic cells (pDCs) as a key producer of type I interferons in lupus, which can be targeted to prevent autoimmunity. Blocking this pathway may offer a potent weapon against the disease.
Research suggests that meerkat predator-scanning behaviour is driven by a desire to protect the group rather than personal safety. When young pups are present, adult meerkats exhibit increased vigilance and sentinel behaviour, indicating a strong sense of cooperation and altruism.
A large study of over 388,000 participants found that high supplemental calcium intake was associated with an increased risk of cardiovascular disease death in men, while dietary calcium intake had no such effect. The study suggests that sex may play a role in the cardiovascular effects of calcium supplements.
Researchers discovered nitric oxide inhibits ERK1/2 signaling pathway, shutting down brain's ability to self-repair after stroke. The study found that excessive nitric oxide production contributes to the severity of stroke and other neurological disorders.
Researchers found that Arabidopsis thaliana plants exhibit genetic traits from older generations, contradicting Mendelian inheritance. New experiments support these findings, providing evidence for novel DNA-based genetic phenomena and implications for plant biology and agriculture.
Researchers found that providing tangible assistance to others significantly reduced mortality rates among the helpers, buffering the negative effects of stress. The study's findings contradict previous research, which failed to establish similar benefits for recipients of social support.
A new therapy called an antisense oligonucleotide (ASO) has been developed by researchers at LSU Health Sciences Center, which partially corrects gene and protein expression and rescues hearing and balance in a mouse model of Usher syndrome. This breakthrough suggests the potential for treating deafness and balance disorders.
A study published in Expert Review of Neurotherapeutics found that 10-15% of people experiencing transient ischemic attacks (TIAs) will suffer full strokes within three months. Rapid evaluation and treatment can reduce the risk of subsequent strokes by up to 80%.
Researchers at Michigan Medicine found that Mary Ingalls likely suffered from viral meningoencephalitis, which caused her blindness, rather than scarlet fever. The study analyzed historical records and Laura Ingalls' memoirs to reach this conclusion.
Decision aids are being reevaluated to determine when it's acceptable to provide a
Researchers at Monell Chemical Senses Center have identified progenitor cells in taste tissue that can differentiate into functional taste cells, potentially helping treat clinical taste dysfunction. The discovery opens up new areas for studying taste cell renewal and contributes to stem cell biology.
A new study finds that state and local health departments often lack involvement in addressing health concerns related to industrial food animal production sites. Community members surveyed reported taking on the role of monitoring and educating themselves due to limited health department engagement.
Researchers at the University of Pittsburgh Cancer Institute have found a way to halt cancer cell growth by depriving them of a key protein. By targeting this process, they discovered a potential new anti-cancer therapy that could work synergistically with existing drugs.
A new kind of pterosaur, Eurazhdarcho langendorfensis, has been identified by scientists from the Transylvanian Museum Society, University of Southampton, and Museau Nacional. The fossilized bones are approximately 68 million years old and belong to the azhdarchids group.
Researchers found that pea aphids can land upright on their feet, using passive rotation to right themselves during free fall. The insects' ability to adapt to extreme situations has been studied in detail and published in Current Biology.
A new PET test using 11C-PIB offers a non-invasive method to visualize amyloid deposits in the heart, providing valuable information for disease prognosis and treatment monitoring. The study demonstrated positive uptake of 11C-PIB in patients with cardiac amyloidosis.
A clinical trial found that treatment with GLP-1 receptor agonists was associated with reduced body mass index and body weight in adolescents with severe obesity. The medication exenatide resulted in a significant reduction in BMI, with an average decrease of 4 percent during the open-label phase.
A new study reveals that amyloid peptides build-up in brain's blood vessels accelerates cognitive decline by limiting oxygen-rich blood and nutrients. Researchers identify CD36 as a key protein in the buildup of Aβ40 in blood vessels, promoting cerebral amyloid angiopathy (CAA).
A study published in the British Journal of Sports Medicine found that watching TV for more than 20 hours a week can almost halve sperm count, while exercising 15 or more hours a week can improve it by 73%. Moderate to vigorous exercise also has a positive impact on semen quality.
Researchers studied two hoodoos in Red Rock Canyon to estimate the force necessary to break sandstone shafts, shedding light on ground motion during recent earthquakes. The study suggests median or low-level ground motion despite large quakes in the area, providing valuable constraints for probabilistic seismic hazard assessments.
A new study finds that shame about past alcoholism is linked to increased risk of relapse and declining physical and mental health in recovering addicts. Behavioral displays of shame were found to predict likelihood of relapse, severity of relapse, and worsening health over time.
The American Association for Pediatric Ophthalmology and Strabismus has revised its guidelines for automated preschool vision screening, focusing on detecting amblyopia risk factors in young children. The new criteria include separate thresholds for different age groups, lower referral rates for young children, and the use of tradition...
JoVE's new Chemistry section publishes a novel experimental approach to study antifreeze proteins, showcasing the potential for these proteins in cryopreservation and tissue preservation. By visualizing dynamic processes, JoVE aims to facilitate reproducible chemistry research.
Climate change is threatening US coastal communities' social, economic, and natural systems, with increased risks of sea-level rise, erosion, storms, and flooding. The report emphasizes the need for coordination and planning to ensure resilience against climate change impacts.
Climate change models predict higher temperatures and months without rainfall, doubling the risk of death in calves up to five years old. The study highlights the importance of protecting vulnerable calves from the effects of climate change.
A cross-sectional study found that around 1 in 10 young teens with mental health issues also drink alcohol, smoke cigarettes, and use cannabis on a weekly basis. The prevalence of this pattern of substance use increases with age and is linked to poorer mental and physical health outcomes.
Researchers at Washington State University have made a breakthrough in repairing damaged brain cells using the active compound of chili peppers. The discovery has potential to provide relief for concussions and other health effects seen in athletes and head-injury victims.
Researchers at the University of Missouri have developed a gold nanoparticle that can transport alpha particles directly to small cancer tumors, reducing damage to healthy organs. The nanoparticle design enables researchers to keep more than 80% of the element inside for extended periods.
Researchers found that melanoma cells can transfer proteins to the immune system, allowing it to gather crucial intelligence and develop cytokines to kill cancer cells. This process, called positive feedback loop, tips the scales in favor of the immune cells.
A Case Western Reserve University researcher is creating ultra-high molecular weight polyethylene with embedded magnetic nanoparticles to monitor degradation and wear. The goal is to make implants more resistant to the environment inside the body.
A research team at the University of Innsbruck has successfully transferred quantum information from an atom to a single photon, paving the way for the construction of a quantum internet. This breakthrough enables the transfer of quantum information over optical channels between quantum computers.
Researchers discovered a novel syndrome caused by mutations in the ASXL3 gene, characterized by non-specific symptoms and intellectual disability. The study provides a molecular definition of this condition, which is difficult to distinguish from Bohring-Opitz syndrome, and highlights the importance of sharing genomic data.
A new study finds that extra-couple transmission accounts for 30% of new HIV infections in men and 10% in women within stable partnerships. Targeting all heterosexual routes of transmission with test-and-treat strategies could be key to fighting the epidemic.
A large population-based study of men found that those taking vitamin C supplements are twice as likely to develop kidney stones as non-supplement users. The risk increased with the frequency of supplement use. Conversely, multivitamin use was not associated with an increased risk of kidney stones.
Researchers developed an ultra-sensitive sensor to detect one molecule of carbon dioxide, improving the accuracy of monitoring and measurement. The sensor technology has the potential to reduce emissions in various industries.
A combined strategy of door-to-door visits and education campaigns is proposed to combat TB in Nunavut. The territory's TB rate is 66 times higher than the general Canadian population, but control can be achieved through a community approach combined with clear performance targets.
A recent study found that the epigenetic marker 5-hydroxymethylcytosine (5hmC) plays a vital role in the selective expression of genes, particularly in healthy brain cells. The study also discovered that changes in 5hmC distribution are associated with gene silencing and may contribute to cancer development.
A study found that conditional cash transfer programs can improve behavior among gay men and male sex workers in Mexico City. Gay men would participate at a rate of over 75% if offered $7-8.75/month, while male sex workers would participate for significantly less, $156/year.
A team of plant geneticists successfully demonstrated that weakening the FEA2 gene can increase meristem size and lead to more rows and kernels in maize plants. This research has significant implications for increasing yields of essential food crops as the global population is projected to reach 8-9 billion by mid-century.
A new study identified two neighboring areas of the cortex as processing different types of visual information independently. The researchers used magnetic fields to disrupt neural activity, revealing that one area plays a causal role in processing orientation, while another underpins shape recognition based on curvature differences.
Researchers have discovered that female hawksbill turtles mate at the beginning of the season and store sperm for up to 75 days, laying multiple nests on beaches. The study also found that these turtles are mainly monogamous, with females pairing up with a single male throughout the breeding season.
Researchers developed a system to artificially simulate natural complex interactions between proteins that regulate genes, allowing for precise control over gene activation. This breakthrough enables scientists to better understand human gene regulation and develop new gene-based therapies.
A team of researchers found that specific acetylation marks on histone H4 determine the balance between two proteins, BRCA1 and 53BP1, controlling DNA repair mechanisms. This balance affects a cell's ability to repair breaks and respond to chemotherapy.
A recent study found that the prescription opioid overdose rate in NYC increased seven-fold between 1990 and 2006, with fatalities concentrated among white residents. The study suggests a different public health approach is needed for this demographic, as their profile differs from heroin consumers.
Researchers at Duke University Medical Center have found that epidermal growth factor speeds the recovery of blood-making stem cells after exposure to radiation. The finding could lead to new treatments for cancer patients and those affected by dirty bombs or nuclear disasters.
Microscopic ocean algae coccolithophores are sensitive to environmental changes and carbon cycle. The study found that different species responded to rapid climate warming events, with some thriving while others declined.
The discovery of the Mcl-1 gene's critical role in keeping antibody-producing cells alive could lead to better treatments for diseases like myeloma and chronic immune disorders. Without this gene, plasma cells die within two days.
A recent study has identified specific genetic mutations that lead to drug resistance and relapse in childhood leukemia. Researchers found 20 relapse-specific mutations, including a mutation in the NT5C2 gene, which may help doctors detect early signs of relapse and switch treatment strategies.
Scientists have visualized molecular changes in a critical protein involved in cell death, providing new insights into apoptosis and its role in disease. The discovery could lead to the development of new medicines that control cell life or death.
A new radiation therapy method using volume-modulated arc therapy (VMAT) has been shown to significantly reduce prostate cancer treatment time by approximately 14%. The study found that VMAT patients had shorter average room times, with some patients experiencing similar treatment times as those using gold-marker tracking.
The National Institutes of Health (NIH) emphasizes the importance of genomic knowledge for nursing care, highlighting its relevance to advancing patient care. Genomic studies published in the Journal of Nursing Scholarship provide insights on genetic applications in nursing practice, including cancer risk assessment and prevention.