Researchers at MIT synthesized and tested 60 fungal compounds, finding some to be potent against human cancer cells. The most effective compounds had specific sulfur atom arrangements and larger attached rings.
Researchers at Eindhoven University of Technology have invented a circuit that makes packaging test possible, reducing food waste by estimating freshness. The ultra-low-cost plastic circuits have numerous potential uses, including pharmaceuticals.
New research suggests that reducing sedentary time by 90 minutes per day can lead to significant health benefits for individuals at high risk of developing type 2 diabetes. The study found that sedentary time was more strongly associated with cardiometabolic markers than total physical activity or vigorous exercise.
A study by 98-year-old researcher Fred Kummerow found that oxidized lipids contribute to heart disease by increasing calcium deposition on the arterial wall and interrupting blood flow. Oxidized cholesterol was also linked to an increased synthesis of a blood-clotting agent, thromboxane.
A new study suggests that consumers select health insurance plans based on both their overall wellness level and anticipated response to having insurance. The research indicates that people with lower behavioral responses to the contract are more likely to opt for high-deductible plans.
Scientists at Tufts University have shown that transplanted eyes can confer vision without a direct neural connection to the brain. The study used frog models and found that ectopic eyes could 'see' and elicit responses similar to those of animals with natural eyes.
Researchers found that clownfish fan their anemone hosts to increase oxygen consumption, benefiting both species. The fish's nocturnal antics may also improve circulation in the anemone, supporting life under low oxygen conditions.
Researchers argue that traditional notions of healthy and successful aging fall short for many Canadians living with chronic diseases. Instead, they advocate for supporting older adults to live well according to their own definitions of health.
Researchers identified a possible treatment window for brain plaques linked to Alzheimer's disease, suggesting that medications may be effective in slowing plaque buildup for several years. The study found that the rate of plaque accumulation accelerates initially before plateauing at high levels.
A team led by Dr. Marie-Josée Hébert discovered a new class of antibodies - anti-LG3 - which can trigger severe rejection episodes and high organ loss rates in kidney transplant patients. This breakthrough holds promise for developing new therapies to prevent or limit organ rejection.
A new study by Grand Valley State University researchers found that NHL teams tend to favor older players, resulting in underestimating the potential of younger players. The study shows that players born between July and December have a higher success rate than those born in the first three months of the year.
A new study reveals that certain viruses, known as bacteriophages, can hijack the immune systems of bacteria to overcome their defenses. This discovery has significant implications for phage therapy, which could potentially treat bacterial infections resistant to antibiotics.
Researchers demonstrate acceleration of electrons by a laser in free space, a significant breakthrough with implications for fusion as a new energy source. The capture-acceleration scenario, proposed by Yu-kun Ho's group, explains how a tightly focused laser can create a channel for electrons to receive energy gain.
Computer scientists from Saarbrücken have developed a new method to scan and monitor Android apps for security-critical functions, allowing users to revoke or grant privileges. The method, known as SRT Appguard, provides real-time policy enforcement for third-party applications and protects user privacy.
Research from Northwestern University and Redeemer University College found that trusting partners remember transgressions as less severe, while low-trust partners recall them as more severe. This distorted memory affects how individuals think about their partner and relationship.
Research found that surviving siblings are more likely to experience a heart attack years after their sibling's death. The risk is higher for women, who face a 25% increased likelihood of heart attack within four to six and a half years after bereavement.
Researchers at Stanford University School of Medicine have identified a new way to block the Hedgehog pathway in skin cancers, which become resistant to treatment. The discovery offers a promising new approach for treating basal cell carcinoma and potentially improving patient outcomes.
Researchers at the University of Michigan are studying how exercise affects lean and obese rats to better understand insulin resistance and muscle glucose uptake. By comparing responses in both groups, they aim to develop more effective treatments for improving health across different populations.
Astronomers have measured the spin rate of a supermassive black hole, providing insights into the galaxy's evolution. The black hole's spin is linked to its accretion disk and can offer clues about the galaxy's past.
A pilot study found six compounds in the breath that increase following stressful mental arithmetic exercises, which may lead to a rapid stress detector. The study's findings are promising but need to be scaled-up with more people and settings before concrete conclusions can be made.
Researchers are working to improve study design and sample collection to better understand the composition and effects of the gut microbiota. The American Gastroenterological Association hosted a World Summit on Gut Microbiota For Health, where experts discussed future research directions.
A line of special liver cells called PICM-19 has the potential to perform many of the same functions as a human liver. The immortal cell line can be used to study various diseases, including liver cancers and cystic fibrosis, and may enable the development of artificial liver devices.
Professor Kevin Resch, a University of Waterloo researcher, has been awarded a $500,000 fellowship to focus on his work in quantum information science. His research could lead to breakthroughs in computing, communications, and cryptography.
Researchers at Duke University found that silver nanoparticles can have adverse effects on plants and microorganisms in low doses, leading to reduced biomass and altered enzyme activity. The study's findings highlight the need for further research into the environmental impact of these particles.
A team of scientists proposes a new system for classifying units of the Geological Time Scale, resolving the debate between single-time and dual-time hierarchies. The proposed realignment maintains both parallel sets of units, allowing for flexibility in choosing one or the other as needed.
Astronomers detect two Type 1a supernovae, designated Supernova 2013X and Supernova 2012ha, which provide valuable information for measuring cosmic distances. The explosions occurred hundreds of millions of years ago and have traveled to Earth, offering insights into the expansion of the universe.
Protection of marine areas from fishing significantly increases fish density and biomass. Even partial protection yields a 50% increase in biomass for target species like lobsters and scallops. However, the success of marine protection depends on its size and management style.
A UK study found that every degree fall in winter air temperature corresponds to a 1.3% drop in ambulance response time. The research analyzed data from Birmingham over five years and showed that extreme weather conditions significantly affected daily ambulance call-outs and response times.
Two high-profile fraud cases in photography have led to millions of dollars in settlements, fueling a revolution in photo conservation research. The cases, which involved fake and altered images, prompted researchers to develop new techniques for conserving and authenticating photographs.
A large-scale genetic study has identified four shared genetic risk loci across five major psychiatric disorders, including bipolar disorder and schizophrenia. The findings suggest that a new classification system based on underlying causes may be possible in the future.
A new UCSF study reveals large price swings in patient charges for the 10 most common outpatient conditions in emergency rooms across the country. The median charge for total outpatient conditions was $1,233, with some patients facing bills of $4 to $24,110.
Researchers from Basque Country describe two new species of Hydnum mushroom, Hydnum ovoideisporum and Hydnum vesterholtii, with distinct ovoid spores and ecological characteristics. The study confirms high genetic diversity among the genus, shedding light on their distribution and ecology.
A tablet-based experiment found that subconcussive head impacts in soccer can cause changes in performance on certain cognitive tasks, particularly those requiring voluntary responses. High school female soccer players were significantly slower than non-players when pointing away from a target.
A recent UEF study reveals that high cell sugar concentrations boost hyaluronan production, which can fuel cancer growth. Regulating hyaluronan levels may hold the key to preventing cancer progression.
The University of Nottingham will lead two innovative manufacturing centres, one in food production and the other in medical devices, with a focus on sustainable food production and cost-effective medical device manufacturing. The £45 million package of investment aims to drive growth and keep the UK ahead in the global race.
A new study published in PLOS ONE finds rapid and point-of-care tests for syphilis are as accurate as conventional laboratory tests, making them a viable solution for resource-limited settings. The findings have major worldwide implications for populations living in rural areas with limited access to healthcare.
Researchers identified a molecule called lipoxin A4 that plays a crucial role in resolving airway inflammation in asthma. This discovery provides new direction for developing next-generation asthma therapies to decrease chronic inflammation.
A researcher at North Carolina State University has created a more efficient method for producing high-density ceramic materials. The new technique, known as selective-melt sintering, allows for the creation of ceramics with no porosity and increased strength in just under a second.
Researchers developed an Adaptation for Conservation Targets (ACT) framework to assess climate change impacts on natural resources. The framework enables scientists and managers to work together to adjust management actions and address the 'What do we do about it?' question.
Researchers analyzed EEGs from autistic children and found a structural difference in brain connections, including increased short-range and decreased long-range connections. This pattern may underlie autism's classic cognitive profile of focused tasks but poor integration across brain areas.
A new genetic analysis of human lice from around the world sheds light on their evolution, disease transmission, and resistance to insecticides. The study's findings suggest that lice can be used as a tool to understand human migration patterns and test ideas about human evolution.
Researchers at the University of Southampton have identified a potential new target for meningitis B vaccination, offering hope for universal protection. The discovery focuses on the Adhesin Complex Protein (ACP), which stimulates the production of antibodies that kill bacteria, providing protection against multiple MenB strains.
A new study investigates the connection between amphibian social habits and a fungus called Batrachochytrium dendrobatidis, which causes Chytridiomycosis. The researchers aim to understand how behavior affects the spread of the disease in California's slender salamander populations.
University of Toronto researchers dominated eight prize categories in this year's Natural Sciences and Engineering Research Council of Canada (NSERC) awards. A total of nine U of T researchers won honours, including Stephen Cook receiving the Gerhard Herzberg Canada Gold Medal for Science and Engineering.
Researchers at Rice University have developed a nanotube-based photodetector that can detect light across the visible and infrared spectrum. The device, made from extra-long carbon nanotubes, promises to make possible new optoelectronic devices, solar cells, and specialized cameras.
A study found that even organic foods not stored, prepared, or cooked in plastic containers can contain phthalates and bisphenol A. High levels of these chemicals were detected in dairy products, spices, and children's bodies.
Researchers at Fred Hutchinson Cancer Center successfully infused large numbers of donor T-cells specific for the Wilm's Tumor Antigen 1 (WT1) to prolong survival in high-risk leukemia patients. The treatment showed improved anti-leukemic activity and reduced graft-vs.-host-disease.
Researchers found that patients with metastatic gastric cancer who underwent both surgery and radiation had better survival rates than those receiving one or no treatment. Radiation therapy also showed promise in reducing symptoms such as pain, obstruction, and bleeding from gastric tumors.
A Wayne State University study found seasonal fluctuations in blood lead levels among children are linked to resuspended dust contaminated with lead. The research, based on nine years of data from over 367,000 children, highlights the need for improved controls to prevent lead exposure.
Research suggests that older people who expect a bleak future are more likely to take precautions to maintain health and safety, leading to better outcomes. Meanwhile, younger individuals tend to have a brighter outlook but may face greater risks of disabilities and death.
Research published in PLOS ONE found that higher indoor humidity levels can significantly reduce the infectivity of influenza virus particles. Indoor humidity above 40% is essential to inactivate flu virus particles, with most inactivation occurring within the first 15 minutes, reducing viral particle infectivity by up to 86%.
Friedreich's Ataxia, a rare genetic disorder, imposes significant annual costs of £11,000 to £19,000 on individuals. The study emphasizes the need for tailored resource allocation to maximize quality of life while minimizing its impact.
A study of over 40,000 Kaiser Permanente patients found no increased risk of infection or complications following total knee replacement (TKR) for those with diabetes. However, patients with uncontrolled diabetes were more likely to be obese and have severe comorbidities.
Researchers use small angle neutron scattering to study ion adsorption in pores of different sizes, understanding how factors like pore size and electrolyte properties affect ion concentration. The technique provides new insights into optimizing energy storage and water desalination systems.
Scientists report new estimates that downgrade additional land available for biofuel production by nearly 80%. The revised estimates suggest 140 million-2.6 billion acres of land can be cultivated for biofuels, compared to previous estimates of 800 million-3.5 billion acres.
The Aquarius instrument captures the first full year of surface salinity data, revealing rapid evolutions of salt patterns in the tropics. Salinity variations drive ocean circulation and provide valuable insights into global climate change.
A new Cochrane systematic review finds starch-based IV fluids used by the NHS cause unnecessary deaths. Researchers conclude that these fluids are more expensive than saline-based crystalloid fluids and increase the risk of death.
A study at the University of Chicago shows that birds' brains coordinate physical actions and brain activity to produce complex movements, similar to how humans govern skilled performance. The research may lead to new ways of understanding human speech production and other complex movements.
Researchers developed a genetically modified protein that reverses vitiligo in mice and shows similar effects on human skin tissue samples. The modified protein, called mutant HSP70i, supplants normal HSP70i, thereby reversing the autoimmune response that causes vitiligo.
Researchers have achieved a major advance in understanding genetic information transcription from DNA to RNA, illuminating critical molecular interactions during the step-by-step process. The study provides new insights into how proteins work together to ensure accurate loading of DNA into Pol II at the start of a gene sequence.
Researchers found that reintroducing normal microbial diversity can eliminate vancomycin-resistant enterococci (VRE) from the intestinal tracts of mice and potentially humans. The study suggests that certain bacterial species, such as Barnesiella, play a key role in preventing colonization by VRE.
A NIH-funded study identifies fundamental math skills needed for functioning in adult life, including number system knowledge. Children who failed to acquire these basic math skills by first grade scored far behind peers by seventh grade on a test of mathematical abilities.
Researchers at Fox Chase Cancer Center found that two antagonistic proteins help keep leukemia at bay by maintaining balance in stem cell production. The study suggests that new compounds could fight cancer by targeting the pathways responsible for regulating these proteins.
VitaThreads, a WPI startup developing biopolymer microthreads for wound healing and tissue regeneration, has made it to the final four in the Association of University Technology Managers' international business plan contest. The company will present its business plan on March 1 in San Antonio, Texas.
New research investigates how social information processing patterns, urgency, and rumination contribute to adolescent mental health disorders. The studies found that Fast Track intervention improved antisocial behavior in youth, while urgency levels predicted depression, and individual differences in distraction shared genetic sources...
Two new species of gorgonian inhabiting barnacles have been found in São Tomé and Príncipe, demonstrating a unique ability to recognize and choose a preferred host. The high degree of symbiotic relationship is believed to be mediated by pheromones, allowing barnacle larvae to determine where to settle.
A national study found same-sex couples who cohabitate have poorer health than their heterosexual married counterparts, despite potential benefits from marriage such as partner insurance and social support. The research may suggest that legalizing same-sex marriage could positively impact the health of these individuals.
Researchers at Case Western Reserve University have validated a questionnaire to assess youth participation in Alcoholics Anonymous (AA)-related helping activities. The Service to Others in Sobriety (SOS) questionnaire shows promise in identifying youths at risk of relapse and promoting recovery.
A novel fabrication technique called selective area atomic layer deposition (ALD) developed by Brian Willis could vastly improve the efficiency of solar rectenna arrays. Rectennas can harness more than 70% of the sun's electromagnetic radiation, converting it into usable electric power.
Bearded capuchin monkeys deliberately place palm nuts in a stable position to crack them open, revealing their capacity for tactile strategy. The researchers found that the monkeys' tool-use skills improved with experience, as they learned to optimize the placement of the nut based on its shape.
A $3 million NIH grant will fund a two-year study investigating the short and long-term consequences of soccer heading on the brain. The researchers, led by Dr. Michael Lipton, will assess the relationship between heading frequency and structural and cognitive measures using advanced MRI technology and cognitive tests.
Researchers have devised a model of oxygen-ion dynamics that contribute to the conductivity of yttria stabilized zirconia (YSZ), a material of great interest in electrochemical devices. By understanding oxygen-ion diffusion, scientists aim to reduce fuel cell operating temperatures from above 700°C to room temperature.
A University of Nebraska-Lincoln study finds that childhood socioeconomic disadvantages and maternal depression increase the risk of major depression and chronic pain in working-aged adults. Hunger experienced in childhood can lead to chronic pain and depression later in life.
A new study found that CRE-positive patients took an average of 387 days to be clear of the organism after hospital discharge. Risk factors for extended carriage included multiple hospitalizations and active infections.
A camera embedded in a rubber-sheathed plastic foam football can record video while in flight, providing a unique ball's-eye view of the field. The researchers developed a computer algorithm that converts raw video into a stable, wide-angle view.
Indiana University neuroscientists have found evidence of source memory in rats, which has implications for future research into the biological underpinnings of memory and the treatment of diseases marked by memory failure. The study provides converging evidence that rats rely on source memory to recall how they acquired information.
A recent study published by the American Sociological Association found that same-sex cohabitors experience poorer self-rated health compared to their heterosexual married counterparts. The study controlled for socioeconomic status and found significant disparities in health between same-sex cohabitors and married individuals.
Researchers at VCU Massey Cancer Center have developed a novel immunotherapy that could work like a vaccine against metastatic cancers. The therapy, called Flagrp-170, uses a molecule engineered to stimulate the immune system and attack cancer cells, with promising results in animal models.
Researchers reveal extraordinary fossil find of fuxianhuiid arthropod with legs used to shovel sediment into the mouth, shedding light on one of Earth's earliest evolutionary examples of complex animal life. The discovery also features the oldest known post-cephalic nervous system, dating back 520 million years.
A large epidemiological study found that increased sugar availability was linked to higher diabetes rates, independent of obesity. The researchers analyzed data from 175 countries and found a 1% increase in diabetes prevalence for every additional 150 calories of sugar per person per day.
Bioengineering researchers at UC Santa Barbara found that changing the shape of chemotherapy drug nanoparticles from spherical to rod-shaped made them up to 10,000 times more effective at targeting and delivering anti-cancer drugs to breast cancer cells. The rod-shaped nanoparticles were engineered with an antibody called trastuzumab t...
Researchers have successfully revived ancient enzymes that enable antibiotic-resistant bacteria to thrive. The 2-3 billion-year-old proteins were reconstructed and studied for their stability, structure, and function, offering insights into the evolution of antibiotic resistance.
Surgeons who played games on a Nintendo Wii improved certain metrics of performance on laparascopies. The study found that Wii-trained surgeons showed significant improvements in economy of instrument movements and efficient cautery.
Researchers used NuSTAR to observe X-rays emitted by hot gas near a supermassive black hole, ruling out obscuring clouds and conclusively measuring its spin rate. The findings provide crucial clues about the fundamental relationship between black holes and their host galaxies.
The University of Nottingham has received two five-year research grants to develop next-gen 'smart' manufacturing systems that can adapt quickly to changes in product requirements and technology. These systems will enable self-repair, self-adaptation, and reconfiguration with low-cost maintenance.
Research published in PLOS ONE found that children with autism spectrum disorders display more social behaviors like talking and physical contact when interacting with animals than with toys. The presence of animals also increases instances of smiling and laughing, and reduces negative behaviors.
Scientists have created a new water-repellent coating that rapidly absorbs water molecules preventing freezing and allows larger droplets to form as flattened droplets. This coating could be used in various applications such as automobile windshields and camera lenses.
A study by the Helmholtz Centre for Environmental Research found a link between high vitamin D levels in expectant mothers and increased infant allergy risks. Mothers with low vitamin D levels had fewer food allergies in their children, while those with high levels had higher risks.
A small study found that babies born to overweight or obese mothers already have thickened artery walls, a sign of heart disease. This finding suggests that maternal weight may contribute to a child's risk of cardiovascular disease later in life.
Scientists at Johns Hopkins Medicine have identified 25 human proteins that may be critical to HIV-1's ability to infect new cells. These proteins are found in viruses from two different types of infected cells, providing a potential target for diagnosis and treatment.
The Fermi Gamma-ray Space Telescope's complex motion is visualized as a Spirograph-like pattern from the pulsar Vela. The pattern captures the spacecraft's 95-minute orbit around Earth and its precession, a slow circuit every 54 days. This data also shows the LAT's nodding pattern to capture the entire sky.