A study published in JAMA Network found that aliskiren, a renin inhibitor, did not slow the progression of coronary artery disease in patients with prehypertension. The treatment had no significant impact on atheroma burden or regression of fatty deposits.
A new study from Washington University in St. Louis finds that IT monitoring can significantly reduce employee theft and fraud in the restaurant industry, resulting in a 7% increase in revenue per restaurant. The study used monitoring software to track sales data of employees and found a 22% drop in theft after implementation.
A recent study at Le Bonheur Children's Hospital found that Pedi-Flite improved outcomes for pediatric diabetic patients, reducing the need for hospital admissions. The system also saved over $760,000 by avoiding 439 ED visits and 115 admissions.
A new review of dozens of studies involving twins found that genetics significantly affect parenting behavior. Children's genetically-influenced characteristics influence how they are parented, with 23% of differences in parenting attributed to a child's genotype.
A study published in Cell identifies a subset of proteins in the brain that persist for longer than a year, potentially revealing the molecular basis of aging. These long-lived proteins are thought to be the 'weakest link' in the aging proteome and may play a role in cellular aging.
The study found that different PCV immunization schedules resulted in similar antibody levels in infants, with some schedules being superior for specific serotypes. The researchers conclude that optimal timing of the primary series is crucial to maintain optimal antibody levels during the period between the primary series and the boost...
A recent study by the European Society of Cardiology found that aliskiren did not improve coronary artery disease progression in patients with prehypertension. However, exploratory findings suggested potential benefits for patients with pre-existing coronary artery disease and blood pressure levels treated to goal.
Researchers have identified a potential new target for breast cancer treatment: ERBB3, an oncogene that promotes tumor growth. The study also found peritoneal dialysis to be effective in reducing brain damage after stroke by lowering glutamate levels.
Researchers at Indiana University found that asexual lineages are more susceptible to extinction due to fast-paced gene conversion processes. This process exposes pre-existing deleterious recessive mutations, contributing to the decline of asexual populations.
A study of nursing students in the UK found that 100% observed lapses in infection prevention and control practices during clinical placements. The most frequently observed events were hand hygiene violations, including failure to clean hands between patients and wearing nail polish or extensions.
A new study from Wake Forest Baptist Medical Center shows that community-supported agriculture (CSA) programs can increase fresh fruit and vegetable access in under-resourced communities. The program provided participants with a weekly box of produce and educational sessions, resulting in increased consumption and satisfaction.
Scientists at Brookhaven National Laboratory identified a signature to look for in superconductors, suggesting that fluctuating charge stripes may play a role. The researchers used neutrons to analyze the material's electronic structure and found that the displacements from average structure persisted with increasing temperature.
An animal study shows that sleep increases the reproduction of oligodendrocytes, which form myelin in the brain and spinal cord, doubling their numbers during rapid eye movement sleep. This could lead to new insights into the role of sleep in brain repair and growth.
A multinational study of over 140,000 participants from 17 countries found a significant gap in hypertension detection and control, with only half aware of their diagnosis and one-third being treated effectively. The study highlights the need for substantial improvement in hypertension diagnosis and treatment.
A systematic review of 12 studies confirms a positive impact on cognitive function associated with higher adherence to a Mediterranean diet. However, results for mild cognitive impairment are inconsistent, highlighting the need for further research.
Researchers at BIDMC are investigating a new noninvasive therapy called Spinal Associative Stimulation (SAS) that combines TMS and peripheral nerve stimulation to activate weakened muscles in patients with spinal cord injuries. SAS aims to increase voluntary activation of residual undamaged spinal-cord fibers, promoting clinical recovery.
Researchers at Cardiff University have made a breakthrough in treating acute pancreatitis by reducing calcium flow into pancreatic cells, stopping the root cause of the disease. The study shows promise for developing an effective treatment for this often fatal disease.
A study found that older adults undergoing spinal stenosis surgery are at higher risk of major medical complications. Preoperative factors such as ASA class and spinal fusion significantly increased the risk of heart attack, stroke, pneumonia, and sepsis.
The proposed system combines ultracold trapped ions and fermionic atoms to emulate solid state physics, including the Peierls transition and phonon-mediated interactions. This hybrid system may simulate complex quantum systems beyond current computing power.
The American Society for Radiation Oncology (ASTRO) has selected 10 outstanding members to receive the Fellow of ASTRO designation. These distinguished individuals have made substantial contributions to the field of radiation oncology through research, education, patient care, and leadership.
A Michigan State University study demonstrates that birds communicate via scents and that odor reliably predicts reproductive success. Researchers found that males with a 'male-like' smell and females with a 'female-like' smell had higher genetic reproductive success, influencing mate selection.
Researchers developed a new method to control genes by targeting transcription, allowing for positive and negative regulation with the same protein. The technique has the potential to enable complex synthetic biology circuits and applications such as disease detection and drug production.
Scientists at the University of Sheffield have identified a synthetic drug, ursodeoxycholic acid (UDCA), that may slow down Parkinson's progression by making faulty mitochondria work normally again. This breakthrough discovery has the potential to improve symptoms and possibly halt disease progression.
A global study has found that many patients don't know they have hypertension and, even if they do, too few are receiving adequate drug therapy for their hypertension. The study found 46.5% of those with hypertension were aware of the diagnosis, while blood pressure was controlled among 32.5% of those being treated.
A new study from the University of Southern California examines how teenagers' online social networking sites influence their smoking and alcohol use. The researchers found that exposure to friends' online pictures of partying or drinking was significantly associated with both smoking and alcohol use.
A University of Missouri study found that posting crisis information on Facebook can improve an organization's public image and reduce perceived severity of the crisis. Researchers measured participants' attitudes before and after exposure to Facebook posts from fictional universities' main accounts.
The AQUARIUS trial found that Aliskiren reduced major cardiovascular events and slowed atherosclerosis progression in patients with prehypertension. The study suggests these patients may benefit from more aggressive treatment of their blood pressure to reduce risk of death, stroke, and heart attack.
Fires burned extensively across Bolivia in late August, fueled by agricultural blazes. The MODIS satellite captured high-resolution images of the infernos, showing thick smoke plumes blocking visibility.
A study of 98,658 Chinese adults found nearly 12% had diabetes and 50% were at risk for prediabetes. The prevalence varied by age, sex, urban vs. rural residence, and economic development.
A study found that iron supplementation among children in a malaria-endemic area did not increase the incidence of malaria. However, hospital admission rates were higher in the iron group compared to the no-iron group.
Researchers discovered a population of neurons in juvenile songbirds that enable the birds to recognize and learn vocal sounds. This finding could provide valuable insights into the neural mechanisms underlying human infant language acquisition.
Researchers successfully resynchronized cardiac motion following a heart attack using engineered stem cells, preventing heart failure. The breakthrough introduces 'biological resynchronization' as a novel means to treat cardiac dyssynchrony.
A study published in PLOS Medicine found that nearly 54% of individuals diagnosed with HIV presented late to clinics, with some populations experiencing increased late presentation. Early diagnosis and treatment are crucial for better health outcomes and reducing the risk of transmission.
A Johns Hopkins study reveals that only 245 robotic surgery complications were reported to the FDA out of 1 million procedures since 2000. The researchers found that many incidents went unreported, and a standardized reporting system is needed to improve safety.
Researchers developed a diagram of the brain circuitry enabling interplay between motor system and auditory system. This discovery could provide insight into schizophrenia and mood disorders, where individuals hear voices others do not.
Employers view visible tattoos as a stigma, perceiving them as making employees look dirty or unsavory. However, certain innocuous symbols like flowers or butterflies are seen as acceptable. The stigma surrounding tattoos is expected to decrease over time as younger generations increasingly get tattoos.
International experts agree on priority areas for preconception care, including cost-effective integration into health programs, increasing healthcare provision through community workers, and reducing tobacco smoke exposure. The goal is to improve pregnancy outcomes by preparing women for optimal health before conception.
Dermatomyositis patients with antibodies against NXP-2 and TIF-1γ have a high risk of cancer, according to new tests developed by researchers. The assays detect these specific proteins in patient blood samples, helping clinicians identify those at highest cancer risk.
A randomized trial found that a fixed-dose combination medication for blood pressure, cholesterol, and platelet control resulted in significantly improved medication adherence after 15 months. The study also showed modest but significant improvements in systolic blood pressure and low-density lipoprotein cholesterol levels.
Researchers at University of Bristol found that removing the carotid body, a small nodule on each carotid artery, reduces blood pressure in rodents with high blood pressure. The discovery has potential to revolutionize treatment for millions suffering from the condition.
Researchers at Penn University have developed a computer model to optimize the properties of metal nanowire networks for flexible touchscreens. The model helps identify the optimal balance between transparency and electrical resistance, leading to improved device performance.
A recent report by the American Academy of Neurology highlights a significant increase in strokes among adolescents and young adults, with approximately 532,000 cases occurring between ages 18-44 in the US. The study emphasizes the need for greater awareness and research into reducing the economic burden of strokes on this age group.
A team of researchers from the University of Michigan discovered that the loss of motor ability associated with aging begins in neurons and spreads to muscles. By stimulating neurons, they were able to reverse the decline in motor ability in roundworms and potentially develop a new treatment for human muscle decline.
A study of French Tour de France cyclists found they lived 41% longer than the general population, with cancer and cardiovascular disease being less common causes of death compared to the general public.
A new study by Ohio State University researchers found that replication-dependent histone isoforms have distinct cellular functions and play a role in cancer development. The study showed that changes in expression of these isoforms can influence cell proliferation and tumor growth.
Researchers found that ERBB3 expression was enhanced in luminal breast cancers compared to other subtypes. The addition of an ERBB3 antibody promoted cancer cell death and decreased tumor growth in vitro.
Researchers created a synthetic polymer that mimics the binding of HIV to immune system cells, effectively blocking the virus from entering the body. The study suggests this polymer could be used in condoms or vaginal gels to prevent the spread of HIV by sexual contact.
Research presented at ESC Congress found that underweight women with coronary artery disease (CAD) have a 2-fold increased risk of death. Maintaining weight or gaining weight may help reduce this risk in obese women, while losing weight increases the risk in underweight women.
Researchers at UC San Francisco discovered a potential epilepsy drug in zebrafish bred to mimic Dravet Syndrome, a rare genetic disorder. Clemizole, an antihistamine, showed efficacy in preventing seizures in the fish, offering a glimmer of hope for families affected by this debilitating disease.
Researchers have discovered a key role for the follistatin/activin-1-2 switch in regulating regeneration in planarian flatworms. The more severe the tissue loss, the higher the expression of follistatin, which inhibits activin proteins and allows regeneration to begin.
Concordia University has received a $2 million funding to develop new techniques for reducing building energy consumption. Researchers will test smart features, solar panels, and heat-storage technologies to make buildings more efficient and sustainable.
A recent trial by Cleveland Clinic found that the drug RVX-208 failed to improve coronary health in patients with low HDL cholesterol, contradicting previous hopes for an 'HDL-raising' treatment. The study used intravascular ultrasonography to assess plaque buildup and found no significant difference between RVX-208 and placebo.
An Iranian telegraph operator named Yusef proposed an earthquake early warning system in 1909, suggesting a local warning system to save lives. He noticed anomalies in the magnetic needle and used it to urge fellow dwellers to evacuate during a six-second warning period.
Elsevier has launched a new journal dedicated to publishing fundamental and applied research on marine and ocean energy. The first volume is now available for free on ScienceDirect, covering topics such as fluid mechanics, design, and environmental assessment.
Four UCLA researchers received significant funding to advance promising stem cell therapies for HIV/AIDS, prostate cancer, and sickle cell disease. Drs. Jerome Zack, Robert Reiter, Donald Kohn, and Gerald Lipshutz will use the grants to develop innovative treatments with potential to revolutionize disease care.
Scientists have observed water ice and ammonia ice in Saturn's atmosphere for the first time. The new findings suggest that clouds of different chemical compositions can coexist, with water ice making up 22% and ammonia ice 55%.
A new study published in the Journal of Athletic Training found that women who land stiffly or in a 'knock-kneed' position are at higher risk of ACL injuries. The researchers used motion analysis software to monitor landing strategies of 82 physically active men and women, revealing a significant gender disparity in ACL tear rates.
A new study by University of Florida researchers highlights the need for more effective methods in storing genetic data. The study finds that about 70 percent of published genetic sequence comparisons are not publicly accessible, hindering research efforts worldwide.
A new study reveals blind mole-rats are highly resistant to carcinogens and have anti-cancer activity in fibroblast cell culture, unlike lab mice and rats. The findings suggest that hypoxia tolerance, longevity, and cancer resistance are tied together through evolutionary adaptations.
Researchers suggest that anti-PD-1 antibodies could be effective in treating hepatitis C and other persistent viral infections. The study found that animal models with HCV infection showed improved immune function after treatment with PD-1 blocking antibodies.
Researchers developed an animal model simulating eye complications associated with Graves' disease, paving the way for better treatments. The condition causes the thyroid gland to become overactive and produce too much thyroid hormone, leading to eye problems like swelling of tissue behind the eyes causing them to bulge outward.
A recent study published in ESC Congress 2013 found that lead extractions are primarily driven by mechanical issues rather than infections. The European Lead Extraction ConTRolled (ELECTRa) Registry, which analyzed over 1,200 patients, showed that 52% of lead extractions were due to non-infectious causes, such as lead malfunctions.
Researchers identify role of BDNF in controlling brain activity during seizures, potentially leading to new anti-epileptic therapies with fewer side effects. The discovery could help patients who do not respond to current treatments.
Research presented at the ESC Congress found that low body mass index (BMI) is associated with worse cardiovascular outcomes in patients with hypertension and glucose intolerance. Patients with lower BMI had a higher risk of cardiovascular events compared to those with middle or higher BMI, according to the study.
Researchers suggest that trypophobia may stem from a specific visual feature common to poisonous animals, including high contrast energy at midrange spatial frequencies. Studies exploring the phenomenon are underway to shed light on its ingrained nature in everyday objects.
Researchers at the University of Minnesota have discovered a groundbreaking technique for manufacturing nanostructures, enabling smaller and better electrical and optical devices. The breakthrough involves using Scotch Magic tape to create extremely thin gaps through metal layers, with widths controlled on the atomic level.
Researchers at Rice University have created a supercapacitor that operates reliably at temperatures of up to 200 degrees Celsius, overcoming key limitations of conventional energy storage devices. The device uses a clay-based membrane electrolyte, which provides high thermal stability and conductivity.
A long-term study found that infants and children with congestive heart failure and genetic disorders have the lowest transplant-free survival rates. Children diagnosed after one year old with unknown cause have the best outcome, a 97% rate of transplant-free survival.
New research shows that female birds maximize offspring health by mating with multiple males, increasing disease resistance through 'cryptic female choice'. This internal mechanism favors sperm from genetically different males, boosting MHC diversity and enhancing disease resilience.
A study found that nursing homes serving predominantly black residents tend to struggle financially and provide lower quality care, with black residents relying on Medicaid for reimbursement. The researchers suggest addressing the issue through financial incentives and restructuring Medicaid to provide better reimbursement rates.
Tropical Storm Toraji is expected to make landfall in Kyushu and move back over open waters in the Sea of Japan. Strong wind shear from the southwest and interaction with the land are not expected to intensify the storm before it makes landfall.
A new recombinant antibody can detect and isolate mesenchymal stem cells (MSCs) from umbilical cord blood, a nonembryonic source with promising applications in tissue engineering and blood stem cell transplantation. The antibody recognizes an i blood group antigen present on MSCs.
Children with inherited metabolic diseases, hypertrophic cardiomyopathy, or multiple risk factors have worse prognosis. Younger age, lower weight, congestive heart failure, and abnormal left ventricle structure are significant risk factors for death or transplantation.
A new study found that hormone replacement therapy (HRT) use is associated with an increased risk of breast cancer among postmenopausal women, but the relationship varies depending on factors such as race/ethnicity, body mass index (BMI), and breast density. The study suggests that HRT may be used for some women without increasing thei...
Scientists have developed an atom-based analogue for electronic devices using ultra-cold bosonic atoms and quantum dots. The transport of single particles through the chain of quantum dots enables current production in systems with reduced dimensionality.
Researchers develop microcapsules containing BCNU for targeted brain cancer therapy, improving drug delivery and reducing side effects. The uniform spheres provide precise control over drug release, enhancing treatment outcomes.
Scientists identified mechanisms necessary to live without insulin, a breakthrough that could lead to alternative treatments against diabetes. Researchers found leptin regulates glucose levels and reduces the risk of hypoglycemia, offering hope for patients.
Tropical Storm Kiko formed on Sept. 1 and intensified quickly, with maximum sustained winds reaching near 70 mph. However, cooler waters and wind shear weakened the storm, leading to its dissipation by Sept. 4. Meanwhile, another low-pressure system is forming near Mexico's southwestern coast.
Researchers have identified a mechanism by which Sirt1 promotes neural activity in the brain, leading to significant delays in aging and increases in longevity. The study found that mice with increased Sirt1 expression in their brains exhibited dramatic physical changes, including improved muscle structure and vigor.
Scientists estimate a minimum of 320,000 viruses in mammals, which could provide critical information for early detection and mitigation of disease outbreaks. This undertaking would cost approximately $6.3 billion, but limiting discovery to 85% of total viral diversity could bring the cost down to $1.4 billion.
Research by Cardiff University's Dr Surhan Cam found that women with degrees were around 40% - 50% more likely to be under-employed than those with no qualifications. Qualified men were also equally at risk of under-employment as unqualified ones.
UC Riverside researchers have created a novel transparent skull implant made of yttria-stabilized zirconia, allowing doctors to aim laser-based treatments without repeated craniectomies. This technology has strong potential for positive impact on patients with life-threatening neurological disorders.
A team of researchers found multiple roundworm eggs in soil samples taken from Richard III's pelvis, indicating a genuine infection. The presence of no eggs in skull soil and few in surrounding grave soil suggests the infection was internal, not from external contamination.
A new study revolutionizes species identification in taxonomy by introducing a modern revision of millipedes using innovative illustration techniques. The 'revolving SEM images' technology allows for a more detailed understanding of complex morphological features, enabling taxonomists to recognize subtle differences between species.
A University of South Florida-led study suggests that the stress-related protein FKBP51 contributes to the acceleration of Alzheimer's disease. The research found that FKBP51 levels increase with age and partner with Hsp90 to make tau more toxic, leading to brain cell death.
This special issue of Frontiers in Ecology and the Environment brings together diverse perspectives on addressing global environmental challenges. The issue highlights socio-ecological drivers of environmental injustice, explores ways to encourage behavioral change, and emphasizes the role of religion in promoting Earth Stewardship.
A study published in PLOS Medicine found that community voluntary male circumcision services in Orange Farm, South Africa significantly reduced HIV infection levels. The study estimated that without circumcision procedures, the HIV rate among men living in this community would have been 15% in 2011.
A recent study published in the journal Age and Ageing found that stressful life events significantly raise the risk of falls in older men. The research, conducted on 5,994 community-dwelling men over 65, showed that men who experienced serious financial problems or the death of a loved one were more likely to fall.
Scientists estimate a minimum of 320,000 unknown viral agents in mammals alone, potentially causing emerging diseases like SARS and Ebola. The study provides a new strategy to identify total viral diversity and estimate costs of discovery.
Researchers sequenced 147 Mycobacterium bovis genomes to track bovine TB outbreaks, revealing local transmission mechanisms drive the spread of the disease. The study provides unprecedented insight into how the disease spreads and will inform control methods.
Researchers found that coal soot reduced Alpine glacier ice by shrinking them, despite cooler temperatures. European glaciers retreated an average of nearly 1 kilometer between 1860 and 1930 due to industrialization, contradicting previous natural climate shift assumptions.
Researchers from the University of York and Czech institutions discovered five new species of Vesper bats in Senegal, showcasing unexpected genetic diversity. The discovery confirms that West Africa may represent a bio-geographic hotspot with many more species to discover.
The nationwide HBV immunization program, launched in 1984, successfully lowered chronic HBV carrier prevalence, HCC incidence, and mortality of infant fulminant hepatitis in vaccinated birth cohorts. Long-term high-coverage immunization was associated with increased herd immunity and lower IFH mortality rates.
A study by Helmholtz Munich found that increased body weight deteriorates physical health, but improves mental well-being in women. The researchers analyzed data from over 3000 people, revealing the complex relationship between body weight and overall health.
Peritoneal dialysis has been shown to reduce glutamate levels in the blood following a stroke event, potentially preserving brain tissue and function. In a rat model of ischemic stroke, peritoneal dialysis reduced tissue damage in the brain.
A new study suggests that zebrafish carrying a Scn1a mutation can serve as a model for Dravet syndrome, allowing researchers to quickly identify potential treatments. The study found that clemizole, an FDA-approved drug, was effective in inhibiting seizure activity in the mutant fish.
The ATOMIC-AHF study found that omecamtiv mecarbil showed greater dyspnoea relief in the highest dose cohort compared to placebo, with significant dose-related and plasma concentration-related trends. The study also revealed increases in systolic ejection time and reductions in heart rate without decreasing blood pressure.
A new study found that combining multiple medications into one pill improves medication adherence and reduces blood pressure and cholesterol levels. The study involved 2,004 participants in the UK, Ireland, Netherlands, and India, with polypill users taking medications regularly by a third more than usual care.
A new biomarker strategy using troponin and copeptin has the potential to change clinical practice with high patient safety, according to the BIC-8 trial. The strategy significantly increased emergency room discharge rates among patients with suspected ACS.
The Journal of Spinal Cord Medicine has published a new issue focusing on the latest research and treatment developments in spinal cord injury. The issue includes articles on various topics such as botulinum toxin use, urology, neuroscience, rehabilitation psychology, and more.
Researchers found that weight loss significantly improved vascular function in obese individuals, particularly those with high insulin levels. The study suggests that reversing insulin resistance and endothelial dysfunction may represent key therapeutic targets for cardiovascular risk reduction.
A variant of FGF21, LY2405319, has been shown to improve metabolism in obese humans with type 2 diabetes by reducing LDL cholesterol and triglycerides while increasing HDL cholesterol levels. The hormone also reduced body weight and fasting insulin, and increased adiponectin.
The University of Tennessee is working with local community partners to improve disaster preparedness and community wellness in Clay County, Kentucky. The project aims to address health and disaster readiness needs through a comprehensive assessment and implementation of solutions.
A study by USC researchers found that 20% of tweets contain location data, including active location monitoring and ambient location data. The researchers developed an app, Twitter2GIS, to analyze metadata and map user locations.
Researchers at Helmholtz Centre for Environmental Research discovered a protein called Abcb4 in zebrafish embryos that transports and expels toxic chemicals, protecting the embryo. However, certain environmental chemicals render this protective mechanism ineffective, making fish embryos more sensitive to toxic substances.