The study found that sensor-augmented pump therapy significantly reduced the rate of severe and moderate hypoglycemia among patients with type 1 diabetes, particularly those with impaired awareness. The technology demonstrated potential to reduce the duration and frequency of significant hypoglycemia.
A study found that dextrose gel treatment can almost halve the likelihood of hypoglycaemia treatment failure in at-risk babies. Babies treated with dextrose gel were less likely to be admitted to intensive care and formula fed, reducing hospital admissions and costs.
Researchers at Henry Ford Hospital found stereotactic body radiotherapy to be a viable option for elderly patients with localized pancreatic cancer, offering a six-to-seven-month increase in lifespan and minimal side effects. The study also showed that two patients lived nearly two years after treatment.
A UN-backed report highlights the need for a 'total economic approach' to tackle global land degradation, which affects 24% of usable lands and results in estimated annual losses of $40 billion. Adopting sustainable land management practices could raise crop supplies by an estimated 2.3 billion tonnes worth $1.4 trillion.
A recent genetic study challenges the long-held assumption that the Neolithic age marked the beginning of a global population explosion. Researchers found evidence of significant human population expansion dating back to the Paleolithic era, around 60,000-80,000 years ago.
Adult childhood cancer survivors who underwent nephrotoxic therapies or kidney surgery had worse kidney function that did not recover over time. The study found a significant decline in glomerular function after treatment and a higher risk of premature chronic renal failure.
Researchers at Penn Medicine have developed a novel immunotherapy approach that demonstrates substantial tumor regression in patients with advanced pancreatic cancer. The treatment combines gemcitabine with an agonist CD40 antibody and uses real-time FDG/PET-CT imaging to monitor tumor response.
Researchers found that genetic loss of a proton pump in beta-intercalated cells leads to increased prostaglandin E2 production, promoting hypokalemia and hypercalcemia. Pharmacologic inactivation also results in dRTA-like symptom development.
Researchers develop mouse model of hereditary spastic paraplegia linked to changes in endoplasmic reticulum structure associated with REEP1 mutations, which impair ER function. The new model provides insight into how ER morphology affects axon loss in HSP.
Researchers evaluated nine commonly used anaesthetics and found that several cause stress responses in zebrafish. Etomidate was deemed the most suitable for future routine use, improving the welfare standards of millions of fish used in scientific research worldwide.
A fleet of underwater robots, known as gliders, is being deployed by NOAA and partners to collect ocean data off the East Coast. The gliders will help scientists improve storm intensity forecasts and understanding of hurricanes.
Researchers develop mouse models of hereditary spastic paraplegia and distal renal tubular acidosis to understand the molecular mechanisms underlying these diseases. The studies reveal key roles for REEP1 in ER shaping and β-intercalated cells in maintaining fluid and electrolyte balance.
Iowa State University researchers have discovered the binding site of a protein that loosens plant cell walls, allowing plants to grow. The discovery uses advanced NMR technology and could lead to more efficient bioenergy production.
A neuroimaging study found that individuals with psychopathy fail to activate brain areas associated with empathy and concern for others when imagining others in pain. This atypical pattern of activation suggests that psychopaths may not care for others, but could be triggered into emotional response through cognitive-behavior therapies.
A clinical decision rule, known as the Ottawa SAH Rule, has been developed to identify neurologically intact patients with headache in the emergency department who have subarachnoid hemorrhage. The rule uses five variables from a patient's history and examination to predict diagnosis, showing 100% sensitivity but only 15.3% specificity.
The Sociogenomics Initiative RCN will bring together researchers from prominent US and Canadian universities to study the genomic mechanisms underlying social behavior. The network aims to establish a comprehensive understanding of social behavior in molecular terms through large-scale collaboration and multidisciplinary approaches.
The study found a significantly lower quality of life in patients who received high-dose radiation therapy (74 Gy) compared to those receiving standard dose (60 Gy). IMRT was associated with a lower decline in QOL compared to 3-D CRT, even a year after treatment.
A study of over 2,200 children's hospital visits reveals racial and ethnic disparities in pain management and length of stay for abdominal pain. Black and Hispanic children were less likely to receive analgesics, while black patients had shorter hospital stays compared to white children.
A Loyola Medicine study found that the i-STAT point-of-care device is not accurate enough to determine troponin levels without a corrective term. Fingerstick testing can accurately qualify troponin levels as negative, borderline or positive.
Researchers at Stanford University have created a theoretical framework to understand and predict the conductive properties of polymeric semiconductors. Their model reveals that the entangled structure of polymers, which allows them to bend, also impedes their ability to conduct electricity.
Cancer-killing natural killer (NK) cells are controlled by the epigenetic process involving enzyme MYSM1, which regulates gene expression and cell maturation. The study paves the way for developing more effective immunotherapies against cancer.
Researchers have created a transparent, elastic OLED that can be repeatedly stretched, folded and twisted at room temperature while still retaining its original shape. The new material has potential applications in smartphones, clothing, lighting, medical tools and more.
Research reveals that high 'bad' cholesterol levels stimulate production of hematopoietic stem/progenitor cells, which promote inflammation and atherosclerosis. The study opens up a potential new approach to preventing heart attack and stroke by focusing on interactions between cholesterol and these cells.
The updated guidelines offer recommendations for vaccination of household pet cats, shelter house cats, and cats in breeding catteries based on risk assessment. The new protocols prioritize comprehensive physical examinations and consultation to determine each cat's specific vaccination requirements.
A $451,000 US grant will fund research on the Chaman Fault in Western Pakistan to improve earthquake prediction and mitigation. The study aims to determine fault movement speed and activity levels to reduce casualties and economic losses.
Researchers found that hyperlink films follow conventional social patterns, with an average of 31.4 characters important for plot development, similar to the size of an affinity group in contemporary society. This challenges the idea that these films can create a more complex and interconnected world.
A clinical trial aims to determine the optimal timing of delivery for preterm pregnancies complicated by poor fetal growth. The study compares three groups and shows better-than-expected health outcomes for the babies, with low mortality rates and minimal severe health issues.
A new study published by Cincinnati Children's Hospital Medical Center found a strong link between exposure to diesel exhaust and increased asthma severity in children. The research suggests that neutralizing the protein IL-17A could be a useful potential therapeutic strategy to counteract the effects of traffic-related air pollution.
Research suggests that young children may struggle to remember overlapping elements of events, such as time and place, until later childhood. This has significant implications for learning in school and the reliability of testimony in court cases.
The SUPREN research group has developed a method to produce acetals from glycerol, which improves the properties of biodiesel. The new process shows higher efficiency and lower costs compared to traditional methods, making it a promising solution for reducing environmental impact.
A study published in JAMA Neurology found that prenatal exposure to antiepileptic drugs was associated with impaired fine motor skills in children at age 6 months. However, breastfeeding by mothers taking these medications was not linked to adverse development in children up to 36 months old.
A parental survey to measure vaccine hesitancy was linked to children's underimmunization rates. Parents with higher survey scores were more likely to have underimmunized children, highlighting the potential for such surveys as a predictive tool.
A secondary analysis of the historic RTOG 9202 prostate cancer trial found no additional benefits with long-term hormonal therapy compared to short-term therapy in intermediate-risk patients. The study suggests that administering less treatment can reduce side effects and healthcare costs without compromising survival rates.
Researchers found that bacteria deviate from the 'just in time' principle for protein production, adapting dynamically to environmental conditions. They use strategies to optimize protein production, which can be useful in fighting pathogens.
A new family of non-precious metal catalysts developed by the UNIST research team exhibits better performance than platinum in oxygen-reduction reaction, offering a solution for widespread commercialization of fuel cell technology. The catalysts show high electrocatalytic activity and superior long-term durability.
Typhoon Pabuk strengthened as it moved north through the northwestern Pacific Ocean, with NASA's Aqua satellite capturing an infrared image that showed powerful thunderstorms east of its center. The storm was expected to turn northeast and bring rain and gusty winds to eastern Japan.
Seventy-five percent of participants reported being bullied by a sibling, and 85% reported bullying a sibling. Sibling bullying is often viewed as normative, with victims and perpetrators evaluating instances differently.
A multidisciplinary team at UT Arlington is developing a smart rehabilitation system that can adapt and personalize therapy programs based on a patient's needs. The iRehab system uses multisensory data to produce the best possible rehabilitation program guidelines for patients, improving treatment effectiveness.
A study found that avoiding specific regions of the brain during whole-brain radiotherapy prevents memory loss in patients. Limiting radiation to the hippocampus, a sensitive area for memory function, preserved memory function for up to six months after treatment.
Researchers have developed a wastewater treatment device that uses spinning CDs coated with zinc oxide nanorods to break down organic pollutants in sewage. The device can treat contaminated water at an impressive rate of 150 mL per minute, making it a promising solution for small-scale water purification.
Researchers found no evidence of an increased risk for specific major birth defects in mothers who received the flu shot. However, there was a slight increase in preterm delivery rates among vaccinated women during certain seasons.
A CDC and Massachusetts General Hospital study finds that pretravel consultations and preventive medications can save money for both payers and most travelers. The study analyzed data from over 1,000 travelers to West Africa and found that the costs associated with contracting malaria outweighed the costs of preventive care.
According to Swedish Research Council study, humans have musical talent due to synchronized group movement, which enhances sound perception in nature. This behavior has survival value, producing dopamine, leading to rhythmic movements and eventually music.
Mobile devices could increase access to pulse oximetry, a crucial tool for monitoring blood oxygen levels, by providing an affordable and effective alternative to traditional equipment. This technology has the potential to improve patient outcomes, particularly in resource-poor settings where timely intervention can be life-saving.
A new study found that children with specific heart birth defects are at a higher risk of developing infective endocarditis, a serious bacterial infection. The risk is especially high in those with heart defects associated with cyanosis and cardiac surgery within the past six months.
Peter Barrance, a senior research scientist at Kessler Foundation, received the 2013 Clinical Biomechanics Award for his study on tibiofemoral contact location changes associated with lateral heel wedging. The study used weight-bearing MRI and was funded by NIDRR.
Researchers from Wildlife Conservation Society and Zoological Society of London capture images of golden eagle attacking a young sika deer on camera trap. The event, which occurred six years ago, is extremely rare and has no impact on deer populations.
Bacteria use TamA protein to channel protein domains across the outer membrane, overcoming additional barrier for nutrient and toxin transport. This process is crucial for infections by pathogens like Yersinia, Salmonella, and Cholera.
Researchers at Rice University have developed a secure system to protect wireless implantable medical devices from unauthorized access. The technology uses the patient's unique heartbeat as a password, which can only be accessed through touch with a programmer device. This provides a secure way to monitor patients and prevent potential...
Researchers found that patients diagnosed with early Alzheimer's disease who received brain imaging test results had better clinical outcomes, including superior executive function and memory abilities. The study suggests that earlier diagnosis can lead to significant benefits, potentially saving healthcare dollars.
A multidisciplinary team has identified the function of an enzyme and its biochemical pathway in a marine bacterium, using computational methods combined with laboratory techniques. This breakthrough sheds light on protein-coding genes and offers insights into the role of orthologous enzymes in similar pathways.
Researchers at Tel Aviv University have developed spring-like fibers to engineer cardiac tissue that can pump more like the real thing. The new fibers show improved elasticity and contraction force compared to straight fibers, holding promise for repairing damaged heart tissue.
Typhoon Usagi made landfall in Guangdong Province on September 22 with maximum sustained winds near 110 mph, displacing over 310,000 residents and causing widespread destruction. Heavy rainfall rates reached up to 6.7 inches per hour along China's coast.
A complete genomic analysis of sorghum reveals its potential for alternative uses beyond grain production. Researchers hope to apply the findings to other feedstocks like miscanthus and sugarcane, while improving drought-resistant lines for food and fuel applications.
Researchers use X-ray facility to replicate high-pressure conditions, finding fractures nucleate at the onset of olivine-to-spinel transition. This discovery confirms earlier experimental work and provides strongest evidence yet that phase transformations trigger deep earthquakes.
The Sangre por Salud Biobank is a collaboration among Mayo Clinic, Mountain Park Health Center, and Arizona State University to support studies in obesity, metabolism and diabetes in the Latino population. The biobank aims to enroll 2,000 participants over four years, with a special emphasis on cardiometabolic risk and obesity.
The American College of Physicians recommends weight loss and continuous positive airway pressure (CPAP) as initial treatment for obstructive sleep apnea. ACP also suggests mandibular advancement devices as an alternative for patients who prefer it or have trouble with CPAP.
A new study found that even long-term abstinence from cocaine does not result in a complete normalization of brain circuitry. Former cocaine users showed differences in reward processing and impulsivity compared to healthy controls, indicating pre-existing risk factors for addiction.
Researchers found that donors prioritize fatalities over those affected when deciding how much to donate. However, a simple change in terminology can reverse this bias, prioritizing the number of homeless individuals. By diverting attention from fatalities to survivors, aid can be allocated more effectively.
A team of researchers has carried out the first detailed measurements of a unique kind of magnetism found in herbertsmithite. The study reveals a signature in the material's optical conductivity that supports theoretical predictions about the influence of magnetism on electrons.